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ChemicalBook >> CAS DataBase List >> 1627710-50-2

1627710-50-2

1627710-50-2 price.
  • $32 - $1600
  • Product name: 1627710-50-2
  • CAS: 1627710-50-2
  • MF: C22H21F2N3O
  • MW: 381.42
  • EINECS:
  • MDL Number:
  • Synonyms:LJH685;Phenol, 2,6-difluoro-4-[4-[4-(4-methyl-1-piperazinyl)phenyl]-3-pyridinyl]-;CS-2182;LJH-685;LJH 685;LJH685;LJH685(LJH-685);2,6-Difluoro-4-[4-[4-(4-methyl-1-piperazinyl)phenyl]-3-pyridinyl]phenol;LJH685,S6K,LJH-685,Apoptosis,inhibit,Ribosomal S6 Kinase (RSK),LJH 685,Inhibitor
21 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Apolloscientific
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number5353DW
  • Product description2,6-Difluoro-4-{4-[4-(4-Methylpiperazin-1-Yl)phenyl]pyridin-3-Yl}phenol
  • Packaging5mg
  • Price$226
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number5353DW
  • Product description2,6-Difluoro-4-{4-[4-(4-Methylpiperazin-1-Yl)phenyl]pyridin-3-Yl}phenol
  • Packaging10mg
  • Price$336
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6170
  • Product descriptionLJH685
  • Packaging5mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0262
  • Product descriptionLjh685
  • Packaging5mg
  • Price$153
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0262
  • Product descriptionLjh685
  • Packaging10mg
  • Price$254
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0262
  • Product descriptionLjh685
  • Packaging50mg
  • Price$1015
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19913
  • Product descriptionLJH685 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19913
  • Product descriptionLJH685 ≥98%
  • Packaging5mg
  • Price$116
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19913
  • Product descriptionLJH685 ≥98%
  • Packaging10mg
  • Price$214
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19913
  • Product descriptionLJH685 ≥98%
  • Packaging25mg
  • Price$456
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5524
  • Product descriptionLJH685 99.99%
  • Packaging5mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5524
  • Product descriptionLJH685 99.99%
  • Packaging10mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5524
  • Product descriptionLJH685 99.99%
  • Packaging50mg
  • Price$720
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5524
  • Product descriptionLJH685 99.99%
  • Packaging100mg
  • Price$1320
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003124
  • Product descriptionLJH685 98+%
  • Packaging5mg
  • Price$66
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003124
  • Product descriptionLJH685 98+%
  • Packaging10mg
  • Price$111
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 5353DW 2,6-Difluoro-4-{4-[4-(4-Methylpiperazin-1-Yl)phenyl]pyridin-3-Yl}phenol 5mg $226 2021-12-16 Buy
AK Scientific 5353DW 2,6-Difluoro-4-{4-[4-(4-Methylpiperazin-1-Yl)phenyl]pyridin-3-Yl}phenol 10mg $336 2021-12-16 Buy
ApexBio Technology B6170 LJH685 5mg $150 2021-12-16 Buy
Apolloscientific BISN0262 Ljh685 5mg $153 2021-12-16 Buy
Apolloscientific BISN0262 Ljh685 10mg $254 2021-12-16 Buy
Apolloscientific BISN0262 Ljh685 50mg $1015 2021-12-16 Buy
Cayman Chemical 19913 LJH685 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 19913 LJH685 ≥98% 5mg $116 2024-03-01 Buy
Cayman Chemical 19913 LJH685 ≥98% 10mg $214 2024-03-01 Buy
Cayman Chemical 19913 LJH685 ≥98% 25mg $456 2024-03-01 Buy
ChemScene CS-5524 LJH685 99.99% 5mg $120 2021-12-16 Buy
ChemScene CS-5524 LJH685 99.99% 10mg $180 2021-12-16 Buy
ChemScene CS-5524 LJH685 99.99% 50mg $720 2021-12-16 Buy
ChemScene CS-5524 LJH685 99.99% 100mg $1320 2021-12-16 Buy
Crysdot CD31003124 LJH685 98+% 5mg $66 2021-12-16 Buy
Crysdot CD31003124 LJH685 98+% 10mg $111 2021-12-16 Buy

Properties

Boiling point :481.1±45.0 °C(Predicted)
Density :1.257±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :crystalline solid
pka :5.86±0.25(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

LJH685 is a selective and potent RSK inhibitor (1). The p90 ribosomal S6 kinase (RSK) family of serine/threonine kinases is linked to various cancers and its substrate phosphorylation is also related to the regulation of cell survival, proliferation, and cell polarity (2).