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ChemicalBook >> CAS DataBase List >> 1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride

1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride

1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride price.
  • $8 - $1224
  • Product name: 1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride
  • CAS: 1628047-87-9
  • MF: C19H28Cl2N2
  • MW: 355.35
  • EINECS:
  • MDL Number:MFCD28334264
  • Synonyms:1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride;ABT199 intermediate1;abt199 int 1;1-((2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-enyl)methyl)piperazine dihydrochloride;1-((4'-chloro-5,5-demethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl-2yl]methyl)piperazine dihydrochloride;1-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine dihydrochloride;Piperazine, 1-[[2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-, hydrochloride (1:2);1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrah ydro-[1,1'-biphenyl]-2-yl)methy)piperazine dihydrochloride
Price29 Properties Safety Information Description
29 prices
Selected condition：
Brand
  • aablocks
  • AK Scientific
  • Alichem
  • Ambeed
  • American Custom Chemicals Corporation
  • Chemenu
  • Crysdot
  • Matrix Scientific
  • Synthonix
  • TRC
  • Usbiological
Package
  • 5MG
  • 50mg
  • 250.00mg
  • 250mg
  • 1g
  • 1.00g
  • 2.5g
  • 5g
  • 10g
  • 25g
  • 50g
  • 100g
  • Manufactureraablocks
  • Product numberAA001TCO
  • Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride 97%
  • Packaging250mg
  • Price$16
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001TCO
  • Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride 98%(HPLC)
  • Packaging1g
  • Price$18
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001TCO
  • Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride 97%
  • Packaging5g
  • Price$23
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001TCO
  • Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride 97%
  • Packaging25g
  • Price$32
  • Updated2026-05-28
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ11760
  • Product descriptionVenetoclaxIntermediate
  • Packaging100g
  • Price$425
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number1628047879
  • Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride
  • Packaging25g
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA163903
  • Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97%
  • Packaging100g
  • Price$339
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA163903
  • Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97%
  • Packaging25g
  • Price$99
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA163903
  • Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97%
  • Packaging5g
  • Price$33
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA163903
  • Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97%
  • Packaging250mg
  • Price$8
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA163903
  • Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97%
  • Packaging1g
  • Price$13
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0419415
  • Product description1-([2-(4-CHLOROPHENYL)-4,4-DIMETHYLCYCLOHEX-1-EN-1-YL]METHYL)PIPERAZINE DIHYDROCHLORIDE SALT 95.00%
  • Packaging5MG
  • Price$457.89
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM105012
  • Product description1-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine dihydrochloride 95%+
  • Packaging25g
  • Price$58
  • Updated2026-05-26
  • Buy
  • ManufacturerChemenu
  • Product numberCM105012
  • Product description1-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine dihydrochloride 95%+
  • Packaging100g
  • Price$172
  • Updated2026-05-26
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11242994
  • Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride 95+%
  • Packaging10g
  • Price$94
  • Updated2026-05-26
  • Buy
  • ManufacturerMatrix Scientific
  • Product number132846
  • Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride
  • Packaging250.00mg
  • Price$432
  • Updated2026-05-18
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA001TCO 1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride 97% 250mg $16 2026-05-28 Buy
aablocks AA001TCO 1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride 98%(HPLC) 1g $18 2026-05-28 Buy
aablocks AA001TCO 1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride 97% 5g $23 2026-05-28 Buy
aablocks AA001TCO 1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride 97% 25g $32 2026-05-28 Buy
AK Scientific J11760 VenetoclaxIntermediate 100g $425 2021-12-16 Buy
Alichem 1628047879 1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 25g $400 2021-12-16 Buy
Ambeed A163903 1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97% 100g $339 2021-12-16 Buy
Ambeed A163903 1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97% 25g $99 2021-12-16 Buy
Ambeed A163903 1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97% 5g $33 2021-12-16 Buy
Ambeed A163903 1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97% 250mg $8 2021-12-16 Buy
Ambeed A163903 1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97% 1g $13 2021-12-16 Buy
American Custom Chemicals Corporation HCH0419415 1-([2-(4-CHLOROPHENYL)-4,4-DIMETHYLCYCLOHEX-1-EN-1-YL]METHYL)PIPERAZINE DIHYDROCHLORIDE SALT 95.00% 5MG $457.89 2021-12-16 Buy
Chemenu CM105012 1-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine dihydrochloride 95%+ 25g $58 2026-05-26 Buy
Chemenu CM105012 1-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine dihydrochloride 95%+ 100g $172 2026-05-26 Buy
Crysdot CD11242994 1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride 95+% 10g $94 2026-05-26 Buy
Matrix Scientific 132846 1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride 250.00mg $432 2026-05-18 Buy
Next Last

Properties

storage temp. :Inert atmosphere,Room Temperature
Appearance :White to off-white Solid
InChI :InChI=1S/C19H27ClN2.ClH/c1-19(2)8-7-16(14-22-11-9-21-10-12-22)18(13-19)15-3-5-17(20)6-4-15;/h3-6,21H,7-14H2,1-2H3;1H
InChIKey :NRMARNSPIXWGDD-UHFFFAOYSA-N
SMILES :C(N1CCNCC1)C1CCC(C)(C)CC=1C1C=CC(Cl)=CC=1.Cl
CAS DataBase Reference :1628047-87-9

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

1-{[2-(4-Chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine Dihydrochloride is an intermediate used in the preparation of Venetoclax (A112430), which is a potent and selective BCL-2 inhibitor with potent antitumour activity while sparing platelets. Venetoclax is used to treat chronic lymphocytic leukaemic cells and estrogen receptor-positive breast cancer.

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Suppliers and manufacturers

Changzhou Nuobailang Biomedical Technology Co., Ltd. NANJING ZENJI PHARMACEUTICALS EVERSHINE CHEMICAL CO., LIMITED Jinan Daen Pharma Tech Co., Ltd. Shandong Juntai Pharmaceutical Co., Ltd Energy Chemical Adamas Reagent, Ltd. Shanghai Topbiochem Technology Co., Ltd Shanghai Jian Chao Chemical Technology Co., Ltd. Shanghai Sheepchem Co., Ltd.