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ChemicalBook >> CAS DataBase List >> PHENOL,2,2'-SULFONYLBIS[3,4,6-TRICHLORO]-

PHENOL,2,2'-SULFONYLBIS[3,4,6-TRICHLORO]-

PHENOL,2,2'-SULFONYLBIS[3,4,6-TRICHLORO]- price.
  • $62 - $1227
  • Product name: PHENOL,2,2'-SULFONYLBIS[3,4,6-TRICHLORO]-
  • CAS: 1638-41-1
  • MF: C12H4Cl6O4S
  • MW: 456.94
  • EINECS:
  • MDL Number:MFCD00397032
  • Synonyms:PHENOL,2,2'-SULFONYLBIS[3,4,6-TRICHLORO]-;2,2'-Sulfonylbis(3,4,6-trichlorophenol);p38 MAP Kinase Inhibitor IV;p38 MAPK Inhibitor IV;p38 MAP Kinase Inhibitor IV - CAS 1638-41-1 - Calbiochem;Phenol, 3,4,6-trichloro-2-[(2,3,5-trichloro-6-hydroxyphenyl)sulfonyl]-;p38 MAP Kinase Inhibitor IV (B10);p38 MAP Kinase Inhibitor IV,p-38 MAP Kinase Inhibitor IV
18 prices
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  • aablocks
  • AK Scientific
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
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  • 100mg
  • Manufactureraablocks
  • Product numberAA00ANQ9
  • Product descriptionp38 MAPK Inhibitor IV ≥98%
  • Packaging10mg
  • Price$127
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00ANQ9
  • Product descriptionp38 MAPK Inhibitor IV 98%byHPLC
  • Packaging100mg
  • Price$1227
  • Updated2026-05-28
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN5158
  • Product descriptionp38 MAP Kinase Inhibitor IV
  • Packaging100mg
  • Price$750
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth
  • Product numberFP147000
  • Product descriptionP38 MAP Kinase Inhibitor IV
  • Packaging50mg
  • Price$759.5
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFP147000
  • Product descriptionP38 MAP Kinase Inhibitor IV
  • Packaging100mg
  • Price$1218
  • Updated2026-06-04
  • Buy
  • ManufacturerCayman Chemical
  • Product number22219
  • Product descriptionp38 MAPK Inhibitor IV ≥98%
  • Packaging25mg
  • Price$270
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22219
  • Product descriptionp38 MAPK Inhibitor IV ≥98%
  • Packaging25mg
  • Price$297
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number22219
  • Product descriptionp38 MAPK Inhibitor IV ≥98%
  • Packaging5mg
  • Price$62
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22219
  • Product descriptionp38 MAPK Inhibitor IV ≥98%
  • Packaging5mg
  • Price$69
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number22219
  • Product descriptionp38 MAPK Inhibitor IV ≥98%
  • Packaging10mg
  • Price$115
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22219
  • Product descriptionp38 MAPK Inhibitor IV ≥98%
  • Packaging10mg
  • Price$127
  • Updated2026-04-30
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0045449
  • Product descriptionp38 MAP Kinase Inhibitor IV 99.0%
  • Packaging5mg
  • Price$156
  • Updated2026-06-04
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0045449
  • Product descriptionp38 MAP Kinase Inhibitor IV 99.0%
  • Packaging5mg
  • Price$156
  • Updated2026-06-04
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number506153
  • Product descriptionp38 MAP Kinase Inhibitor IV
  • Packaging10mg
  • Price$216
  • Updated2026-04-30
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0543
  • Product descriptionp38 MAP Kinase Inhibitor IV ≥98% (HPLC)
  • Packaging5mg
  • Price$136
  • Updated2026-04-30
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0543
  • Product descriptionp38 MAP Kinase Inhibitor IV ≥98% (HPLC)
  • Packaging25mg
  • Price$440
  • Updated2022-05-15
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00ANQ9 p38 MAPK Inhibitor IV ≥98% 10mg $127 2026-05-28 Buy
aablocks AA00ANQ9 p38 MAPK Inhibitor IV 98%byHPLC 100mg $1227 2026-05-28 Buy
AK Scientific SYN5158 p38 MAP Kinase Inhibitor IV 100mg $750 2021-12-16 Buy
Biosynth FP147000 P38 MAP Kinase Inhibitor IV 50mg $759.5 2026-06-04 Buy
Biosynth FP147000 P38 MAP Kinase Inhibitor IV 100mg $1218 2026-06-04 Buy
Cayman Chemical 22219 p38 MAPK Inhibitor IV ≥98% 25mg $270 2024-03-01 Buy
Cayman Chemical 22219 p38 MAPK Inhibitor IV ≥98% 25mg $297 2026-04-30 Buy
Cayman Chemical 22219 p38 MAPK Inhibitor IV ≥98% 5mg $62 2024-03-01 Buy
Cayman Chemical 22219 p38 MAPK Inhibitor IV ≥98% 5mg $69 2026-04-30 Buy
Cayman Chemical 22219 p38 MAPK Inhibitor IV ≥98% 10mg $115 2024-03-01 Buy
Cayman Chemical 22219 p38 MAPK Inhibitor IV ≥98% 10mg $127 2026-04-30 Buy
ChemScene CS-0045449 p38 MAP Kinase Inhibitor IV 99.0% 5mg $156 2026-06-04 Buy
ChemScene CS-0045449 p38 MAP Kinase Inhibitor IV 99.0% 5mg $156 2026-06-04 Buy
Sigma-Aldrich 506153 p38 MAP Kinase Inhibitor IV 10mg $216 2026-04-30 Buy
Sigma-Aldrich SML0543 p38 MAP Kinase Inhibitor IV ≥98% (HPLC) 5mg $136 2026-04-30 Buy
Sigma-Aldrich SML0543 p38 MAP Kinase Inhibitor IV ≥98% (HPLC) 25mg $440 2022-05-15 Buy

Properties

Melting point :244-245 °C(Solv: ethyl acetate (141-78-6))
Boiling point :590.0±50.0 °C(Predicted)
Density :1.854±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
form :powder
pka :2.43±0.50(Predicted)
color :white to beige
InChI :1S/C12H4Cl6O4S/c13-3-1-5(15)9(19)11(7(3)17)23(21,22)12-8(18)4(14)2-6(16)10(12)20/h1-2,19-20H
InChIKey :AKUKHICVNCCQHN-UHFFFAOYSA-N
SMILES :[S](=O)(=O)(c2c(c(cc(c2O)Cl)Cl)Cl)c1c(c(cc(c1O)Cl)Cl)Cl

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

p38 MAP Kinase Inhibitor IV is a cell permeable sulfone compound which functions as an ATP-competitive inhibitor of p38α and p38β MAP Kinases. In addition, p38 MAP Kinase Inhibitor IV inhibits p38&gamma/δ, ERK1/2, and JNK1/2/3 to a lesser extent. Furthermore, studies indicate that p38 MAP Kinase Inhibitor IV suppresses LPS-induced IL-1&beta release from hPBMC more effectively than SB 203850. Since MAP Kinases are responsible for signal transduction in cascade controlling cellular responses the inhibitor can possibly be used to inhibit apoptosis and other responses to stress stimuli.

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