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ChemicalBook >> CAS DataBase List >> PHORBOL 12-MYRISTATE 13-ACETATE

PHORBOL 12-MYRISTATE 13-ACETATE

PHORBOL 12-MYRISTATE 13-ACETATE price.
  • $37 - $2757.4
  • Product name: PHORBOL 12-MYRISTATE 13-ACETATE
  • CAS: 16561-29-8
  • MF: C36H56O8
  • MW: 616.83
  • EINECS:605-413-5
  • MDL Number:MFCD00036736
  • Synonyms:13-o-acetylphorbol12-myristate ;4)benz(1,2-e)azulen-5-one9a-acetate,(+)-ethyl-5h-cyclopropa( ;5h-cyclopropa(3,4)benz(1,2-e)azulen-5-one,1,1a-beta,1b-alpha,4,4a,7a-beta,7b, ;4BETA-PHORBOL 12-MYRISTATE 13-ACETATE;4BETA,9ALPHA,12BETA,13ALPHA,20-PENTA-HYDROXYTIGLIA-1,6-DIEN-3-ONE 12BETA-MYRISTATE 13-ACETATE;4ALPHA,9ALPHA,12BETA,13ALPHA,20-PENTAHYDROXYTIGLIA-1,6-DIEN-3-ONE 12BETA-MYRISTATE 13-ACETATE;(1AR,1BS,4AR,7AS,7BS,8R,9R,9AS)-9A-(ACETYLOXY)-1A,1B,4,4A,5,7A,7B,8,9,9A-DECAHYDRO-4A,7B-DIHYDROXY-3-(HYDROXYMETHYL)-1,1,6,8-TETRAMETHYL-5-OXO-1H-CYCLOPROPA[3,4]BENZ[1,2-E]AZULEN-9-YL TETRADECANOATE;12-TETRADECANOYL PHORBOL 13-ACETATE
67 prices
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Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
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  • 250mg
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0010-M025
  • Product descriptionPhorbol12-myristate13-acetate[PMA] ≥98%(HPLC)
  • Packaging25mg
  • Price$290
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberV0265
  • Product description12-O-tetradecanoylphorbol-13-acetate
  • Packaging5mg
  • Price$177
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberV0265
  • Product description12-O-tetradecanoylphorbol-13-acetate
  • Packaging100mg
  • Price$1268
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ63916
  • Product descriptionPhorbol 12-myristate 13-acetate, 99+%
  • Packaging1mg
  • Price$105
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ63916
  • Product descriptionPhorbol 12-myristate 13-acetate, 99+%
  • Packaging5mg
  • Price$263
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ63916
  • Product descriptionPhorbol 12-myristate 13-acetate, 99+%
  • Packaging10mg
  • Price$482
  • Updated2024-03-01
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  • ManufacturerAlfa Aesar
  • Product numberJ63916
  • Product descriptionPhorbol 12-myristate 13-acetate, 99+%
  • Packaging25mg
  • Price$861
  • Updated2024-03-01
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  • ManufacturerAmbeed
  • Product numberA175370
  • Product description(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-Acetoxy-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yltetradecanoate 95+%
  • Packaging1mg
  • Price$49
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA175370
  • Product description(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-Acetoxy-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yltetradecanoate 95+%
  • Packaging5mg
  • Price$87
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA175370
  • Product description(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-Acetoxy-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yltetradecanoate 95+%
  • Packaging10mg
  • Price$115
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA175370
  • Product description(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-Acetoxy-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yltetradecanoate 95+%
  • Packaging25mg
  • Price$273
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA175370
  • Product description(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-Acetoxy-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yltetradecanoate 95+%
  • Packaging50mg
  • Price$496
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA175370
  • Product description(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-Acetoxy-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yltetradecanoate 95+%
  • Packaging100mg
  • Price$895
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA175370
  • Product description(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-Acetoxy-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yltetradecanoate 95+%
  • Packaging250mg
  • Price$1796
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN2060
  • Product description12-O-tetradecanoylphorbol-13-acetate(PMA)
  • Packaging5mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBITP1356
  • Product descriptionRecombinant Human Tissue Plasminogen Activator
  • Packaging20μg
  • Price$75
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CN2-0010-M025 Phorbol12-myristate13-acetate[PMA] ≥98%(HPLC) 25mg $290 2021-12-16 Buy
AK Scientific V0265 12-O-tetradecanoylphorbol-13-acetate 5mg $177 2021-12-16 Buy
AK Scientific V0265 12-O-tetradecanoylphorbol-13-acetate 100mg $1268 2021-12-16 Buy
Alfa Aesar J63916 Phorbol 12-myristate 13-acetate, 99+% 1mg $105 2024-03-01 Buy
Alfa Aesar J63916 Phorbol 12-myristate 13-acetate, 99+% 5mg $263 2024-03-01 Buy
Alfa Aesar J63916 Phorbol 12-myristate 13-acetate, 99+% 10mg $482 2024-03-01 Buy
Alfa Aesar J63916 Phorbol 12-myristate 13-acetate, 99+% 25mg $861 2024-03-01 Buy
Ambeed A175370 (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-Acetoxy-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yltetradecanoate 95+% 1mg $49 2021-12-16 Buy
Ambeed A175370 (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-Acetoxy-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yltetradecanoate 95+% 5mg $87 2021-12-16 Buy
Ambeed A175370 (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-Acetoxy-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yltetradecanoate 95+% 10mg $115 2021-12-16 Buy
Ambeed A175370 (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-Acetoxy-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yltetradecanoate 95+% 25mg $273 2021-12-16 Buy
Ambeed A175370 (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-Acetoxy-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yltetradecanoate 95+% 50mg $496 2021-12-16 Buy
Ambeed A175370 (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-Acetoxy-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yltetradecanoate 95+% 100mg $895 2021-12-16 Buy
Ambeed A175370 (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-Acetoxy-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yltetradecanoate 95+% 250mg $1796 2021-12-16 Buy
ApexBio Technology N2060 12-O-tetradecanoylphorbol-13-acetate(PMA) 5mg $110 2021-12-16 Buy
Apolloscientific BITP1356 Recombinant Human Tissue Plasminogen Activator 20μg $75 2021-12-16 Buy

Properties

Melting point :65-79oC
Boiling point :571.87°C (rough estimate)
Density :1.17±0.1 g/cm3 (20 ºC 760 Torr)
refractive index :1.4900 (estimate)
storage temp. :-20°C
solubility :DMSO: DMSO solutions can be stored dark at −20°C for at least six months.soluble
pka :11.19±0.70(Predicted)
form :Fine Crystalline Powder
color :Off-white to light yellow
Water Solubility :Very soluble in methanol, soluble in DMSO, chloroform, ethanol or acetone, ether, ethyl acetate, DMF or acetonitrile. Insoluble in water.
Sensitive :Light Sensitive
BRN :2407201
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
InChIKey :PHEDXBVPIONUQT-RGYGYFBISA-N
CAS DataBase Reference :16561-29-8(CAS DataBase Reference)
EPA Substance Registry System :12-O-Tetradecanoylphorbol 13-acetate (16561-29-8)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

PMA activates Ca2+- ATPase and potentiates forskolin-induced cAMP formation. It has been shown to inhibit apoptosis induced by the Fas antigen, but PMA induces apoptosis in HL-60 promyelocytic leukemia cells.

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