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ChemicalBook >> CAS DataBase List >> N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-CERAMIDE

N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-CERAMIDE

N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-CERAMIDE price.
  • $178 - $1407
  • Product name: N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-CERAMIDE
  • CAS: 202850-01-9
  • MF: C36H61N5O6
  • MW: 659.9
  • EINECS:
  • MDL Number:MFCD02259239
  • Synonyms:C12 NBD-CERAMIDE;C12-NBD Ceramide, N-[12-[(7-Nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-ceramide;N-(NBD-AMINOLAUROYL)CERAMIDE;N-DODECANOYL-NBD-D-ERYTHRO-SPHINGOSINE;N-DODECANOYL-NBD-L-THREO-SPHINGOSINE;N-C12-NBD-L-THREO-SPHINGOSINE;N-C12-NBD-D-ERYTHRO-SPHINGOSINE;N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-CERAMIDE
6 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • Sigma-Aldrich
Package
  • 100μg
  • 1mg
  • 5mg
  • 10mg
  • ManufacturerAK Scientific
  • Product number1644AH
  • Product descriptionC-12NBDCeramide
  • Packaging5mg
  • Price$981
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberLIP0003549
  • Product descriptionN-DODECANOYL-NBD-L-THREO-SPHINGOSINE 95.00%
  • Packaging5MG
  • Price$504.89
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10007958
  • Product descriptionC12 NBD Ceramide (d18:1/12:0) ≥98%
  • Packaging1mg
  • Price$178
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10007958
  • Product descriptionC12 NBD Ceramide (d18:1/12:0) ≥98%
  • Packaging5mg
  • Price$793
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10007958
  • Product descriptionC12 NBD Ceramide (d18:1/12:0) ≥98%
  • Packaging10mg
  • Price$1407
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberN9158
  • Product descriptionN-(NBD-Aminolauroyl)ceramide ≥98%
  • Packaging100μg
  • Price$269
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1644AH C-12NBDCeramide 5mg $981 2021-12-16 Buy
American Custom Chemicals Corporation LIP0003549 N-DODECANOYL-NBD-L-THREO-SPHINGOSINE 95.00% 5MG $504.89 2021-12-16 Buy
Cayman Chemical 10007958 C12 NBD Ceramide (d18:1/12:0) ≥98% 1mg $178 2024-03-01 Buy
Cayman Chemical 10007958 C12 NBD Ceramide (d18:1/12:0) ≥98% 5mg $793 2024-03-01 Buy
Cayman Chemical 10007958 C12 NBD Ceramide (d18:1/12:0) ≥98% 10mg $1407 2024-03-01 Buy
Sigma-Aldrich N9158 N-(NBD-Aminolauroyl)ceramide ≥98% 100μg $269 2024-03-01 Buy

Properties

Melting point :92-93 °C
Density :1.103±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml
form :A crystalline solid
pka :13.54±0.20(Predicted)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Ceramidase catalyzes the hydrolysis of the N-acyl linkage between the fatty acid and sphingosine base in ceramide to produce sphingosine and a free fatty acid. Three isoforms of ceramidases (acid, neutral, and alkaline) have been characterized based on differences in their catalytic pH optimum. C-12 NBD ceramide is a long-chain fluorescent ceramide analog that can be used for the measurement of alkaline and neutral ceramidase activity. It is hydrolyzed efficiently by alkaline ceramidase from P. aeruginosa and by neutral ceramidase from mouse liver. In addition, alkaline and neutral ceramidases from a variety of mammalian cell lines also hydrolyze C-12 NBD ceramide. Acid ceramidase does not appear to utilize C-12 NBD ceramide as a substrate. The possibility exists for C-12 NBD ceramide to also be applied to the measurement of ceramide kinase and/or sphingomyelin synthase activity.

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