3-Quinolinecarboxylic acid, 8-cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b]-1,4-oxazin-6(2H)-yl]-1,4-dihydro-4-oxo-
![3-Quinolinecarboxylic acid, 8-cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b]-1,4-oxazin-6(2H)-yl]-1,4-dihydro-4-oxo- price.](/CAS/GIF/209342-40-5.gif)
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- $104 - $3691
- Product name: 3-Quinolinecarboxylic acid, 8-cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b]-1,4-oxazin-6(2H)-yl]-1,4-dihydro-4-oxo-
- CAS: 209342-40-5
- MF: C20H19FN4O4
- MW: 398.39
- EINECS:
- MDL Number:MFCD13185157
- Synonyms:3-Quinolinecarboxylic acid, 8-cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b]-1,4-oxazin-6(2H)-yl]-1,4-dihydro-4-oxo-;BAY35-3377,finafloxacin hydrochloride;8-cyano-1-cyclopropyl-6-fluoro-7-((4aS,7aS)-hexahydropyrrolo[3,4-b][1,4]oxazin-6(2H)-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid;8-Cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b][1,4]oxazin-6(2H)-yl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid;Finafloxacin (BAY35-3377);100827;(-)-(4aS,7aS)-8-Cyano-1-cyclopropyl-6-fluoro-4-oxo-7-(perhydropyrrolo[3,4-b]-1,4-oxazin-6-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride;Finafloxacin >=95% (HPLC)
35 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- Biosynth
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
Package
- 1mg
- 2.00mg
- 1mL(10mMinDMSO)
- 2mg
- 5.00mg
- 5mg
- 10mg
- 25MG
- 50mg
- 100mg
- Manufactureraablocks
- Product numberAA00BF4P
- Product descriptionFinafloxacin >98%
- Packaging5mg
- Price$380
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BF4P
- Product descriptionFinafloxacin >98%
- Packaging10mg
- Price$585
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BF4P
- Product descriptionFinafloxacin >98%
- Packaging50mg
- Price$1591
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BF4P
- Product descriptionFinafloxacin >98%
- Packaging100mg
- Price$2202
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberO32773
- Product description8-Cyano-1-cyclopropyl-6-fluoro-7-((4aS,7aS)-hexahydropyrrolo[3,4-b][1,4]oxazin-6(2H)-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 98%
- Packaging25MG
- Price$1350
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO32773
- Product description8-Cyano-1-cyclopropyl-6-fluoro-7-((4aS,7aS)-hexahydropyrrolo[3,4-b][1,4]oxazin-6(2H)-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 98%
- Packaging5MG
- Price$450
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number9092CS
- Product descriptionFinafloxacin
- Packaging10mg
- Price$1805
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberBA1120
- Product descriptionFinafloxacin
- Packaging10mg
- Price$418
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberBA1120
- Product descriptionFinafloxacin
- Packaging1mg
- Price$104
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberBA1120
- Product descriptionFinafloxacin
- Packaging5mg
- Price$261
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberBA1120
- Product descriptionFinafloxacin
- Packaging1mL(10mMinDMSO)
- Price$287
- Updated2026-05-06
- Buy
- ManufacturerBiosynth
- Product numberFC138682
- Product descriptionFinafloxacin
- Packaging5mg
- Price$1499.2
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFC138682
- Product descriptionFinafloxacin
- Packaging25mg
- Price$3373.25
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFC138682
- Product descriptionFinafloxacin
- Packaging10mg
- Price$1949
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFC138682
- Product descriptionFinafloxacin
- Packaging2mg
- Price$989.48
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFC138682
- Product descriptionFinafloxacin
- Packaging1mg
- Price$674.64
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00BF4P | Finafloxacin >98% | 5mg | $380 | 2026-05-28 | Buy |
| aablocks | AA00BF4P | Finafloxacin >98% | 10mg | $585 | 2026-05-28 | Buy |
| aablocks | AA00BF4P | Finafloxacin >98% | 50mg | $1591 | 2026-05-28 | Buy |
| aablocks | AA00BF4P | Finafloxacin >98% | 100mg | $2202 | 2026-05-28 | Buy |
| ACHEMBLOCK | O32773 | 8-Cyano-1-cyclopropyl-6-fluoro-7-((4aS,7aS)-hexahydropyrrolo[3,4-b][1,4]oxazin-6(2H)-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 98% | 25MG | $1350 | 2026-05-27 | Buy |
| ACHEMBLOCK | O32773 | 8-Cyano-1-cyclopropyl-6-fluoro-7-((4aS,7aS)-hexahydropyrrolo[3,4-b][1,4]oxazin-6(2H)-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 98% | 5MG | $450 | 2026-05-27 | Buy |
| AK Scientific | 9092CS | Finafloxacin | 10mg | $1805 | 2021-12-16 | Buy |
| ApexBio Technology | BA1120 | Finafloxacin | 10mg | $418 | 2026-05-06 | Buy |
| ApexBio Technology | BA1120 | Finafloxacin | 1mg | $104 | 2026-05-06 | Buy |
| ApexBio Technology | BA1120 | Finafloxacin | 5mg | $261 | 2026-05-06 | Buy |
| ApexBio Technology | BA1120 | Finafloxacin | 1mL(10mMinDMSO) | $287 | 2026-05-06 | Buy |
| Biosynth | FC138682 | Finafloxacin | 5mg | $1499.2 | 2026-06-04 | Buy |
| Biosynth | FC138682 | Finafloxacin | 25mg | $3373.25 | 2026-06-04 | Buy |
| Biosynth | FC138682 | Finafloxacin | 10mg | $1949 | 2026-06-04 | Buy |
| Biosynth | FC138682 | Finafloxacin | 2mg | $989.48 | 2026-06-04 | Buy |
| Biosynth | FC138682 | Finafloxacin | 1mg | $674.64 | 2026-06-04 | Buy |
Properties
Boiling point :686.2±55.0 °C(Predicted)
Density :1.57±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO : 6.4 mg/mL (16.06 mM)
pka :6.38±0.50(Predicted)
form :powder
color :white to beige
InChIKey :FYMHQCNFKNMJAV-HOTGVXAUSA-N
SMILES :Fc1cc2c([n](cc([c]2=O)C(=O)O)C5CC5)c(c1N3C[C@@H]4NCCO[C@H]4C3)C#N
Density :1.57±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO : 6.4 mg/mL (16.06 mM)
pka :6.38±0.50(Predicted)
form :powder
color :white to beige
InChIKey :FYMHQCNFKNMJAV-HOTGVXAUSA-N
SMILES :Fc1cc2c([n](cc([c]2=O)C(=O)O)C5CC5)c(c1N3C[C@@H]4NCCO[C@H]4C3)C#N
Safety Information
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| Signal word: | Danger | ||||||||||||||
| Hazard statements: |
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Description
Finafloxacin, an antimicrobial agent of the 8-cyano subclass of fluoroquinolones, was approved by the US FDA in December 2014 for treatment of acute otitis externa, commonly known as swimmer’s ear, caused by susceptible strains of Pseudomonas aeruginosa and Staphylococcus aureus. Finafloxacin was developed by MerLion Pharmaceuticals in partnership with Bayer Health Care Pharmaceuticals, and the drug was licensed by Mer- Lion to Alcon (a division of Novartis) for development and commercialization for ear infections in North America. In contrast to other marketed fluoroquinolones, which display reduced activity in slightly acidic environments, finafloxacin exhibits increased antibacterial activity at pH 5–6, with minimum inhibitory concentration values that are 4- to 8-fold lower than at neutral pH. It is highly selective for bacterial type II topoisomerases, which are involved in bacterial DNA replication, transcription, repair, and recombination, and has broad spectrum antibacterial activity against Gram-positive and Gram-negative strains, including ciprofloxacin-resistant strains.More related product prices
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