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ChemicalBook >> CAS DataBase List >> 9-OXO-11ALPHA,15S-DIHYDROXY-PROST-13E-EN-1-OIC-3,3,4,4-D4 ACID

9-OXO-11ALPHA,15S-DIHYDROXY-PROST-13E-EN-1-OIC-3,3,4,4-D4 ACID

9-OXO-11ALPHA,15S-DIHYDROXY-PROST-13E-EN-1-OIC-3,3,4,4-D4 ACID price.
  • $78 - $3960
  • Product name: 9-OXO-11ALPHA,15S-DIHYDROXY-PROST-13E-EN-1-OIC-3,3,4,4-D4 ACID
  • CAS: 211105-33-8
  • MF: C20H30D4O5
  • MW: 358.51
  • EINECS:
  • MDL Number:MFCD00216050
  • Synonyms:ALPROSTADIL-D4;9-OXO-11ALPHA,15S-DIHYDROXY-PROST-13E-EN-1-OIC-3,3,4,4-D4 ACID;PROSTAGLANDIN E1-D4;(11α,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic Acid-d4;3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-cyclopentaneheptanoic Acid-d4;Alprox TD-d4;Caveject-d4;Liprostin-d4
4 prices
Selected condition:
Brand
  • Cayman Chemical
  • TRC
Package
  • 50μg
  • 100μg
  • 500μg
  • 10mg
  • ManufacturerCayman Chemical
  • Product number313010
  • Product descriptionProstaglandin E1-d4 ≥99% deuterated forms (d1-d4)
  • Packaging50μg
  • Price$78
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number313010
  • Product descriptionProstaglandin E1-d4 ≥99% deuterated forms (d1-d4)
  • Packaging100μg
  • Price$140
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number313010
  • Product descriptionProstaglandin E1-d4 ≥99% deuterated forms (d1-d4)
  • Packaging500μg
  • Price$582
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberP838602
  • Product descriptionProstaglandinE1-d4
  • Packaging10mg
  • Price$3960
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 313010 Prostaglandin E1-d4 ≥99% deuterated forms (d1-d4) 50μg $78 2024-03-01 Buy
Cayman Chemical 313010 Prostaglandin E1-d4 ≥99% deuterated forms (d1-d4) 100μg $140 2024-03-01 Buy
Cayman Chemical 313010 Prostaglandin E1-d4 ≥99% deuterated forms (d1-d4) 500μg $582 2024-03-01 Buy
TRC P838602 ProstaglandinE1-d4 10mg $3960 2021-12-16 Buy

Properties

solubility :DMF: >100 mg/ml (from PGE1); DMSO: >50 mg/ml (from PGE1); Ethanol: >50 mg/ml (from PGE1); PBS pH 7.2: >1.6 mg/ml (from PGE1)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Prostaglandin E1-d4 (PGE1-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of PGE1 by GC- or LC-mass spectrometry. PGE1 is the theoretical cyclooxygenase metabolite of dihomo-γ-linolenic acid (DGLA), but it is virtually undetectable in the plasma of normal humans or other animals. Its pharmacology includes vasodilation, hypotension, and anti-platelet activities. The IC50 of PGE1 for the inhibition of ADP-induced human platelet aggregation is 40 nM. The vasorelaxant and anti-hypertensive effects of PGE1 are used to treat male erectile dysfunction and to provide emergency vasodilation of the patent ductus arteriosus in infants whose cardiac anomalies require pulmonary shunting for survival. In human males, the intracavernosal effective dose range for PGE1 is 2 to 80 μg, and the transurethral range is 125 to 1,000 μg.