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ChemicalBook >> CAS DataBase List >> (2R)-2-[[6-[(3-CHLORO-4-CARBOXYPHENYL)AMINO]-9-(1-METHYLETHYL)-9H-PURIN-2-YL]AMINO]-3-METHYL-1-BUTANOL

(2R)-2-[[6-[(3-CHLORO-4-CARBOXYPHENYL)AMINO]-9-(1-METHYLETHYL)-9H-PURIN-2-YL]AMINO]-3-METHYL-1-BUTANOL

(2R)-2-[[6-[(3-CHLORO-4-CARBOXYPHENYL)AMINO]-9-(1-METHYLETHYL)-9H-PURIN-2-YL]AMINO]-3-METHYL-1-BUTANOL price.
  • $13 - $2986.9
  • Product name: (2R)-2-[[6-[(3-CHLORO-4-CARBOXYPHENYL)AMINO]-9-(1-METHYLETHYL)-9H-PURIN-2-YL]AMINO]-3-METHYL-1-BUTANOL
  • CAS: 212844-54-7
  • MF: C20H25ClN6O3
  • MW: 432.9
  • EINECS:
  • MDL Number:MFCD04118312
  • Synonyms:(2R)-2-[[6-[(3-CHLORO-4-CARBOXYPHENYL)AMINO]-9-(1-METHYLETHYL)-9H-PURIN-2-YL]AMINO]-3-METHYL-1-BUTANOL;PURVALANOL B;NG 95;(2R)-2-((6-((3-Chloro-4-carboxyphenyl)amino)-9-(1-methylethyl)-9H-purin-2-yl)amino)-3-methyl-1-butanol;NG 95, (2R)-2-[[6-[(3-Chloro-4-carboxyphenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol;Purvalanol B, >=96%;(R)-2-Chloro-4-((2-((1-hydroxy-3-methylbutan-2-yl)amino)-9-isopropyl-9H-purin-6-yl)amino)benzo;Purvalanol B(NG 95)
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  • aablocks
  • Aaron Chemicals
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  • Adipogen Life Sciences
  • AK Scientific
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  • ChemScene
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  • 10mM*1mLinDMSO
  • 1mg
  • 2mg
  • 5mg
  • 50
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  • 25mg
  • 50.00mg
  • 50mg
  • 100MG
  • 100.00mg
  • 10
  • 10mM(in1mLDMSO)
  • 250mg
  • 200mg
  • 10mM(in 1mL DMSO)
  • 10mM*1mLinDMSO(Solution)
  • 1000mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 1g
  • Manufactureraablocks
  • Product numberAA0039P7
  • Product description2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98%
  • Packaging10mg
  • Price$44
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA0039P7
  • Product description2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98%
  • Packaging25mg
  • Price$87
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA0039P7
  • Product description2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98%
  • Packaging5mg
  • Price$28
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA0039P7
  • Product description2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98%
  • Packaging2mg
  • Price$16
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA0039P7
  • Product description2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98%
  • Packaging1mg
  • Price$13
  • Updated2026-05-28
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  • ManufacturerAaron Chemicals
  • Product numberAR003AGZ
  • Product description2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98%
  • Packaging25mg
  • Price$86
  • Updated2026-06-03
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  • ManufacturerAaron Chemicals
  • Product numberAR003AGZ
  • Product description2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98%
  • Packaging1mg
  • Price$18
  • Updated2026-06-03
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  • ManufacturerAaron Chemicals
  • Product numberAR003AGZ
  • Product description2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98%
  • Packaging2mg
  • Price$21
  • Updated2026-06-03
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  • ManufacturerAaron Chemicals
  • Product numberAR003AGZ
  • Product description2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98%
  • Packaging5mg
  • Price$26
  • Updated2026-06-03
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  • ManufacturerAaron Chemicals
  • Product numberAR003AGZ
  • Product description2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98%
  • Packaging10mg
  • Price$43
  • Updated2026-06-03
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  • ManufacturerAaron Chemicals
  • Product numberAR003AGZ
  • Product description2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98%
  • Packaging50mg
  • Price$146
  • Updated2026-06-03
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  • ManufacturerACHEMBLOCK
  • Product numberY229137
  • Product descriptionPurvalanol B 97.00%
  • Packaging50MG
  • Price$195
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberY229137
  • Product descriptionPurvalanol B 97.00%
  • Packaging100MG
  • Price$350
  • Updated2026-05-27
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1070-M050
  • Product descriptionPurvalanol B ≥95%
  • Packaging50mg
  • Price$416
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1070-M100
  • Product descriptionPurvalanol B ≥95%
  • Packaging100mg
  • Price$713
  • Updated2026-05-06
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  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1070-M010
  • Product descriptionPurvalanol B ≥95%
  • Packaging10mg
  • Price$108
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA0039P7 2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98% 10mg $44 2026-05-28 Buy
aablocks AA0039P7 2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98% 25mg $87 2026-05-28 Buy
aablocks AA0039P7 2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98% 5mg $28 2026-05-28 Buy
aablocks AA0039P7 2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98% 2mg $16 2026-05-28 Buy
aablocks AA0039P7 2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98% 1mg $13 2026-05-28 Buy
Aaron Chemicals AR003AGZ 2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98% 25mg $86 2026-06-03 Buy
Aaron Chemicals AR003AGZ 2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98% 1mg $18 2026-06-03 Buy
Aaron Chemicals AR003AGZ 2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98% 2mg $21 2026-06-03 Buy
Aaron Chemicals AR003AGZ 2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98% 5mg $26 2026-06-03 Buy
Aaron Chemicals AR003AGZ 2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98% 10mg $43 2026-06-03 Buy
Aaron Chemicals AR003AGZ 2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98% 50mg $146 2026-06-03 Buy
ACHEMBLOCK Y229137 Purvalanol B 97.00% 50MG $195 2026-05-27 Buy
ACHEMBLOCK Y229137 Purvalanol B 97.00% 100MG $350 2026-05-27 Buy
Adipogen Life Sciences SYN-1070-M050 Purvalanol B ≥95% 50mg $416 2026-05-06 Buy
Adipogen Life Sciences SYN-1070-M100 Purvalanol B ≥95% 100mg $713 2026-05-06 Buy
Adipogen Life Sciences SYN-1070-M010 Purvalanol B ≥95% 10mg $108 2026-05-06 Buy

Properties

Melting point :58.5 °C
Boiling point :660.6±65.0 °C(Predicted)
Density :1.43±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: 37 mg/mL, soluble
form :solid
pka :2.81±0.25(Predicted)
color :White to light yellow
InChIKey :ZKDXRFMOHZVXSG-HNNXBMFYSA-N
SMILES :CC(C)[C@H](CO)Nc1nc(Nc2ccc(C(O)=O)c(Cl)c2)c3ncn(C(C)C)c3n1

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. Purvalanol B is a CDK inhibitor that most potently inhibits Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p35, and Cdk2/cyclin B (IC50s = 6, 9, 6, and 6 nM, respectively). It is inactive against Cdk4/cyclin D1 as well as several other protein kinases. Purvalanol B is a 2,6,9-trisubstituted purine that, at micromolar doses, inhibits the growth of parasites, including Plasmodium.

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