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ChemicalBook >> CAS DataBase List >> (2R)-2-[[6-[(3-CHLORO-4-CARBOXYPHENYL)AMINO]-9-(1-METHYLETHYL)-9H-PURIN-2-YL]AMINO]-3-METHYL-1-BUTANOL

(2R)-2-[[6-[(3-CHLORO-4-CARBOXYPHENYL)AMINO]-9-(1-METHYLETHYL)-9H-PURIN-2-YL]AMINO]-3-METHYL-1-BUTANOL

(2R)-2-[[6-[(3-CHLORO-4-CARBOXYPHENYL)AMINO]-9-(1-METHYLETHYL)-9H-PURIN-2-YL]AMINO]-3-METHYL-1-BUTANOL price.
  • $41 - $2986.9
  • Product name: (2R)-2-[[6-[(3-CHLORO-4-CARBOXYPHENYL)AMINO]-9-(1-METHYLETHYL)-9H-PURIN-2-YL]AMINO]-3-METHYL-1-BUTANOL
  • CAS: 212844-54-7
  • MF: C20H25ClN6O3
  • MW: 432.9
  • EINECS:
  • MDL Number:MFCD04118312
  • Synonyms:(2R)-2-[[6-[(3-CHLORO-4-CARBOXYPHENYL)AMINO]-9-(1-METHYLETHYL)-9H-PURIN-2-YL]AMINO]-3-METHYL-1-BUTANOL;PURVALANOL B;NG 95;(2R)-2-((6-((3-Chloro-4-carboxyphenyl)amino)-9-(1-methylethyl)-9H-purin-2-yl)amino)-3-methyl-1-butanol;NG 95, (2R)-2-[[6-[(3-Chloro-4-carboxyphenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol;Purvalanol B, >=96%;(R)-2-Chloro-4-((2-((1-hydroxy-3-methylbutan-2-yl)amino)-9-isopropyl-9H-purin-6-yl)amino)benzo;Purvalanol B(NG 95)
34 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 2mg
  • 50
  • 1mg
  • 10
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 10mM(in 1mL DMSO)
  • 1000mg
  • 1g
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1070-M001
  • Product descriptionPurvalanol B ≥95%
  • Packaging1mg
  • Price$54
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3984AH
  • Product descriptionPurvalanol B
  • Packaging10mg
  • Price$159
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA176253
  • Product descriptionPurvalanol B 98+%
  • Packaging2mg
  • Price$51
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA176253
  • Product descriptionPurvalanol B 98+%
  • Packaging5mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA176253
  • Product descriptionPurvalanol B 98+%
  • Packaging10mg
  • Price$117
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA176253
  • Product descriptionPurvalanol B 98+%
  • Packaging50mg
  • Price$198
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000206
  • Product descriptionPURVALANOL B 95.00%
  • Packaging1MG
  • Price$166.95
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000206
  • Product descriptionPURVALANOL B 95.00%
  • Packaging10MG
  • Price$745.85
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000206
  • Product descriptionPURVALANOL B 95.00%
  • Packaging50MG
  • Price$1417.71
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8565
  • Product descriptionPurvalanol B
  • Packaging10mg
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8565
  • Product descriptionPurvalanol B
  • Packaging10mM(in 1mL DMSO)
  • Price$132
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8565
  • Product descriptionPurvalanol B
  • Packaging50mg
  • Price$448
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS032175
  • Product descriptionPurvalanol B
  • Packaging2mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS032175
  • Product descriptionPurvalanol B
  • Packaging5mg
  • Price$89
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181107
  • Product descriptionPurvalanol B(NG-95) >98%
  • Packaging100mg
  • Price$765
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181107
  • Product descriptionPurvalanol B(NG-95) >98%
  • Packaging250mg
  • Price$1504.5
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences SYN-1070-M001 Purvalanol B ≥95% 1mg $54 2021-12-16 Buy
AK Scientific 3984AH Purvalanol B 10mg $159 2021-12-16 Buy
Ambeed A176253 Purvalanol B 98+% 2mg $51 2021-12-16 Buy
Ambeed A176253 Purvalanol B 98+% 5mg $90 2021-12-16 Buy
Ambeed A176253 Purvalanol B 98+% 10mg $117 2021-12-16 Buy
Ambeed A176253 Purvalanol B 98+% 50mg $198 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000206 PURVALANOL B 95.00% 1MG $166.95 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000206 PURVALANOL B 95.00% 10MG $745.85 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000206 PURVALANOL B 95.00% 50MG $1417.71 2021-12-16 Buy
ApexBio Technology A8565 Purvalanol B 10mg $95 2021-12-16 Buy
ApexBio Technology A8565 Purvalanol B 10mM(in 1mL DMSO) $132 2021-12-16 Buy
ApexBio Technology A8565 Purvalanol B 50mg $448 2021-12-16 Buy
Arctom AS032175 Purvalanol B 2mg $50 2021-12-16 Buy
Arctom AS032175 Purvalanol B 5mg $89 2021-12-16 Buy
Biorbyt Ltd orb181107 Purvalanol B(NG-95) >98% 100mg $765 2021-12-16 Buy
Biorbyt Ltd orb181107 Purvalanol B(NG-95) >98% 250mg $1504.5 2021-12-16 Buy

Properties

Melting point :58.5 °C
Boiling point :660.6±65.0 °C(Predicted)
Density :1.43±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: 37 mg/mL, soluble
form :solid
pka :2.81±0.25(Predicted)
InChIKey :ZKDXRFMOHZVXSG-HNNXBMFYSA-N

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. Purvalanol B is a CDK inhibitor that most potently inhibits Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p35, and Cdk2/cyclin B (IC50s = 6, 9, 6, and 6 nM, respectively). It is inactive against Cdk4/cyclin D1 as well as several other protein kinases. Purvalanol B is a 2,6,9-trisubstituted purine that, at micromolar doses, inhibits the growth of parasites, including Plasmodium.

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