(2R)-2-[[6-[(3-CHLORO-4-CARBOXYPHENYL)AMINO]-9-(1-METHYLETHYL)-9H-PURIN-2-YL]AMINO]-3-METHYL-1-BUTANOL
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- $13 - $2986.9
- Product name: (2R)-2-[[6-[(3-CHLORO-4-CARBOXYPHENYL)AMINO]-9-(1-METHYLETHYL)-9H-PURIN-2-YL]AMINO]-3-METHYL-1-BUTANOL
- CAS: 212844-54-7
- MF: C20H25ClN6O3
- MW: 432.9
- EINECS:
- MDL Number:MFCD04118312
- Synonyms:(2R)-2-[[6-[(3-CHLORO-4-CARBOXYPHENYL)AMINO]-9-(1-METHYLETHYL)-9H-PURIN-2-YL]AMINO]-3-METHYL-1-BUTANOL;PURVALANOL B;NG 95;(2R)-2-((6-((3-Chloro-4-carboxyphenyl)amino)-9-(1-methylethyl)-9H-purin-2-yl)amino)-3-methyl-1-butanol;NG 95, (2R)-2-[[6-[(3-Chloro-4-carboxyphenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol;Purvalanol B, >=96%;(R)-2-Chloro-4-((2-((1-hydroxy-3-methylbutan-2-yl)amino)-9-isopropyl-9H-purin-6-yl)amino)benzo;Purvalanol B(NG 95)
88 prices
Selected condition:
Brand
- aablocks
- Aaron Chemicals
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- Tocris
- TRC
Package
- 10mM*1mLinDMSO
- 1mg
- 2mg
- 50
- 5mg
- 10mg
- 25mg
- 50.00mg
- 50mg
- 100MG
- 100.00mg
- 10
- 200mg
- 10mM*1mLinDMSO(Solution)
- 10mM(in1mLDMSO)
- 10mM(in 1mL DMSO)
- 250mg
- 1000mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 1g
- Manufactureraablocks
- Product numberAA0039P7
- Product description2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98%
- Packaging1mg
- Price$13
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0039P7
- Product description2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98%
- Packaging2mg
- Price$16
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0039P7
- Product description2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98%
- Packaging5mg
- Price$28
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0039P7
- Product description2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98%
- Packaging10mg
- Price$44
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0039P7
- Product description2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98%
- Packaging25mg
- Price$87
- Updated2026-05-28
- Buy
- ManufacturerAaron Chemicals
- Product numberAR003AGZ
- Product description2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98%
- Packaging50mg
- Price$146
- Updated2026-06-03
- Buy
- ManufacturerAaron Chemicals
- Product numberAR003AGZ
- Product description2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98%
- Packaging1mg
- Price$18
- Updated2026-06-03
- Buy
- ManufacturerAaron Chemicals
- Product numberAR003AGZ
- Product description2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98%
- Packaging2mg
- Price$21
- Updated2026-06-03
- Buy
- ManufacturerAaron Chemicals
- Product numberAR003AGZ
- Product description2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98%
- Packaging5mg
- Price$26
- Updated2026-06-03
- Buy
- ManufacturerAaron Chemicals
- Product numberAR003AGZ
- Product description2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98%
- Packaging10mg
- Price$43
- Updated2026-06-03
- Buy
- ManufacturerAaron Chemicals
- Product numberAR003AGZ
- Product description2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98%
- Packaging25mg
- Price$86
- Updated2026-06-03
- Buy
- ManufacturerACHEMBLOCK
- Product numberY229137
- Product descriptionPurvalanol B 97.00%
- Packaging100MG
- Price$350
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY229137
- Product descriptionPurvalanol B 97.00%
- Packaging50MG
- Price$195
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1070-M050
- Product descriptionPurvalanol B ≥95%
- Packaging50mg
- Price$416
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1070-M100
- Product descriptionPurvalanol B ≥95%
- Packaging100mg
- Price$713
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1070-M005
- Product descriptionPurvalanol B ≥95%
- Packaging5mg
- Price$81
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0039P7 | 2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98% | 1mg | $13 | 2026-05-28 | Buy |
| aablocks | AA0039P7 | 2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98% | 2mg | $16 | 2026-05-28 | Buy |
| aablocks | AA0039P7 | 2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98% | 5mg | $28 | 2026-05-28 | Buy |
| aablocks | AA0039P7 | 2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98% | 10mg | $44 | 2026-05-28 | Buy |
| aablocks | AA0039P7 | 2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98% | 25mg | $87 | 2026-05-28 | Buy |
| Aaron Chemicals | AR003AGZ | 2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98% | 50mg | $146 | 2026-06-03 | Buy |
| Aaron Chemicals | AR003AGZ | 2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98% | 1mg | $18 | 2026-06-03 | Buy |
| Aaron Chemicals | AR003AGZ | 2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98% | 2mg | $21 | 2026-06-03 | Buy |
| Aaron Chemicals | AR003AGZ | 2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98% | 5mg | $26 | 2026-06-03 | Buy |
| Aaron Chemicals | AR003AGZ | 2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98% | 10mg | $43 | 2026-06-03 | Buy |
| Aaron Chemicals | AR003AGZ | 2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid 98% | 25mg | $86 | 2026-06-03 | Buy |
| ACHEMBLOCK | Y229137 | Purvalanol B 97.00% | 100MG | $350 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y229137 | Purvalanol B 97.00% | 50MG | $195 | 2026-05-27 | Buy |
| Adipogen Life Sciences | SYN-1070-M050 | Purvalanol B ≥95% | 50mg | $416 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1070-M100 | Purvalanol B ≥95% | 100mg | $713 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1070-M005 | Purvalanol B ≥95% | 5mg | $81 | 2026-05-06 | Buy |
Properties
Melting point :58.5 °C
Boiling point :660.6±65.0 °C(Predicted)
Density :1.43±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: 37 mg/mL, soluble
form :solid
pka :2.81±0.25(Predicted)
color :White to light yellow
InChIKey :ZKDXRFMOHZVXSG-HNNXBMFYSA-N
SMILES :CC(C)[C@H](CO)Nc1nc(Nc2ccc(C(O)=O)c(Cl)c2)c3ncn(C(C)C)c3n1
Boiling point :660.6±65.0 °C(Predicted)
Density :1.43±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: 37 mg/mL, soluble
form :solid
pka :2.81±0.25(Predicted)
color :White to light yellow
InChIKey :ZKDXRFMOHZVXSG-HNNXBMFYSA-N
SMILES :CC(C)[C@H](CO)Nc1nc(Nc2ccc(C(O)=O)c(Cl)c2)c3ncn(C(C)C)c3n1
Safety Information
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| Signal word: | ||||||||
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Description
Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. Purvalanol B is a CDK inhibitor that most potently inhibits Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p35, and Cdk2/cyclin B (IC50s = 6, 9, 6, and 6 nM, respectively). It is inactive against Cdk4/cyclin D1 as well as several other protein kinases. Purvalanol B is a 2,6,9-trisubstituted purine that, at micromolar doses, inhibits the growth of parasites, including Plasmodium.Related product price
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