2 - (4 - Methylphenyl) - 1,2 - benzisothiazol - 3(2H)-one
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- $41 - $2242
- Product name: 2 - (4 - Methylphenyl) - 1,2 - benzisothiazol - 3(2H)-one
- CAS: 2514-30-9
- MF: C14H11NOS
- MW: 241.31
- EINECS:604-604-1
- MDL Number:MFCD05856231
- Synonyms:2 - (4 - Methylphenyl) - 1,2 - benzisothiazol - 3(2H)-one;2-(4-Methylphenyl)-2,3-dihydrobenzisothiazol-3-one;2-p-Tolyl-1,2-benzisothiazolin-3-one;PBIT;PBIT, >=98%;JUMONJI HDM INHIBITOR;CS-1495;2-(4-methylphenyl)-1,2-benzothiazol-3-one
45 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- AvaChem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- Usbiological
Package
- 10mM*1mLinDMSO
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 0.500g
- 500.00mg
- 1.00g
- 1g
- 10g
- Manufactureraablocks
- Product numberAA00BJGQ
- Product description2-(P-Tolyl)Benzo[D]Isothiazol-3(2H)-One ≥98%
- Packaging1mg
- Price$41
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BJGQ
- Product description2-(P-Tolyl)Benzo[D]Isothiazol-3(2H)-One
- Packaging2mg
- Price$56
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BJGQ
- Product description2-(P-Tolyl)Benzo[D]Isothiazol-3(2H)-One
- Packaging10mg
- Price$111
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BJGQ
- Product description2-(P-Tolyl)Benzo[D]Isothiazol-3(2H)-One
- Packaging5mg
- Price$79
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BJGQ
- Product description2-(P-Tolyl)Benzo[D]Isothiazol-3(2H)-One
- Packaging50mg
- Price$323
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BJGQ
- Product description2-(P-Tolyl)Benzo[D]Isothiazol-3(2H)-One
- Packaging25mg
- Price$212
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BJGQ
- Product description2-(P-Tolyl)Benzo[D]Isothiazol-3(2H)-One
- Packaging100mg
- Price$510
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberY226784
- Product descriptionPBIT 97.00%
- Packaging25MG
- Price$260
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY226784
- Product descriptionPBIT 97.00%
- Packaging100MG
- Price$730
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberY1896
- Product description2-(4-methylphenyl)-1,2-benzisothiazol-3(2H)-one
- Packaging25mg
- Price$491
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3584
- Product descriptionPBIT
- Packaging10mg
- Price$217
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC3584
- Product descriptionPBIT
- Packaging5mg
- Price$135
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC3584
- Product descriptionPBIT
- Packaging25mg
- Price$475
- Updated2026-05-06
- Buy
- ManufacturerAvaChem
- Product number6643
- Product descriptionPBIT 98%
- Packaging5mg
- Price$62
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number6643
- Product descriptionPBIT 98%
- Packaging25mg
- Price$240
- Updated2026-05-22
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545928
- Product descriptionPbIT >98%
- Packaging25mg
- Price$416.5
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00BJGQ | 2-(P-Tolyl)Benzo[D]Isothiazol-3(2H)-One ≥98% | 1mg | $41 | 2026-05-28 | Buy |
| aablocks | AA00BJGQ | 2-(P-Tolyl)Benzo[D]Isothiazol-3(2H)-One | 2mg | $56 | 2026-05-28 | Buy |
| aablocks | AA00BJGQ | 2-(P-Tolyl)Benzo[D]Isothiazol-3(2H)-One | 10mg | $111 | 2026-05-28 | Buy |
| aablocks | AA00BJGQ | 2-(P-Tolyl)Benzo[D]Isothiazol-3(2H)-One | 5mg | $79 | 2026-05-28 | Buy |
| aablocks | AA00BJGQ | 2-(P-Tolyl)Benzo[D]Isothiazol-3(2H)-One | 50mg | $323 | 2026-05-28 | Buy |
| aablocks | AA00BJGQ | 2-(P-Tolyl)Benzo[D]Isothiazol-3(2H)-One | 25mg | $212 | 2026-05-28 | Buy |
| aablocks | AA00BJGQ | 2-(P-Tolyl)Benzo[D]Isothiazol-3(2H)-One | 100mg | $510 | 2026-05-28 | Buy |
| ACHEMBLOCK | Y226784 | PBIT 97.00% | 25MG | $260 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y226784 | PBIT 97.00% | 100MG | $730 | 2026-05-27 | Buy |
| AK Scientific | Y1896 | 2-(4-methylphenyl)-1,2-benzisothiazol-3(2H)-one | 25mg | $491 | 2021-12-16 | Buy |
| ApexBio Technology | C3584 | PBIT | 10mg | $217 | 2026-05-06 | Buy |
| ApexBio Technology | C3584 | PBIT | 5mg | $135 | 2026-05-06 | Buy |
| ApexBio Technology | C3584 | PBIT | 25mg | $475 | 2026-05-06 | Buy |
| AvaChem | 6643 | PBIT 98% | 5mg | $62 | 2026-05-22 | Buy |
| AvaChem | 6643 | PBIT 98% | 25mg | $240 | 2026-05-22 | Buy |
| Biorbyt Ltd | orb545928 | PbIT >98% | 25mg | $416.5 | 2021-12-16 | Buy |
Properties
Melting point :136.7-137.1 °C(Solv: benzene (71-43-2); hexane (110-54-3))
Boiling point :418.2±38.0 °C(Predicted)
Density :1.297±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear (warmed)
pka :-0.03±0.20(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Boiling point :418.2±38.0 °C(Predicted)
Density :1.297±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear (warmed)
pka :-0.03±0.20(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Safety Information
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Description
Jumonji AT-rich interactive domain 1 (JARID1) demethylases mediate the removal of methyl groups from trimethylated lysine 4 on histone 3 (H3K4me3). PBIT is a reversible, cell-permeable inhibitor of JARID1 family demethylases (IC50s = 6, 3, 4.9, and 28 μM for JARID1A, JARID1B, JARID1C, and JARID1D, respectively). It does not significantly affect the activity of UTX and JMJD3 demethylases. It increases trimethylation of H3K4 in HeLa cells and blocks the proliferation of tumor cells expressing high levels of JARID1B.More related product prices
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