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ChemicalBook >> CAS DataBase List >> 5-[4-PHENYL-5-(TRIFLUOROMETHYL)-2-THIENYL]-3-[3-(TRIFLUOROMETHYL)PHENYL]-1,2,4-OXADIAZOLE

5-[4-PHENYL-5-(TRIFLUOROMETHYL)-2-THIENYL]-3-[3-(TRIFLUOROMETHYL)PHENYL]-1,2,4-OXADIAZOLE

5-[4-PHENYL-5-(TRIFLUOROMETHYL)-2-THIENYL]-3-[3-(TRIFLUOROMETHYL)PHENYL]-1,2,4-OXADIAZOLE price.
  • $28 - $4480
  • Product name: 5-[4-PHENYL-5-(TRIFLUOROMETHYL)-2-THIENYL]-3-[3-(TRIFLUOROMETHYL)PHENYL]-1,2,4-OXADIAZOLE
  • CAS: 256414-75-2
  • MF: C20H10F6N2OS
  • MW: 440.36
  • EINECS:
  • MDL Number:MFCD00096600
  • Synonyms:SEW 2871;SPHINGOSINE-1-PHOSPATE, RECEPTOR S1P1 AGONIST;SW2871;5-[4-PHENYL-5-(TRIFLUOROMETHYL)-2-THIENYL]-3-[3-(TRIFLUOROMETHYL)PHENYL]-1,2,4-OXADIAZOLE;5-[4-PHENYL-5-(TRIFLUOROMETHYL)THIOPHEN-2-YL]-3-[3-(TRIFLUOROMETHYL)PHENYL]1,2,4-OXADIAZOLE;BUTTPARK 82\12-95;SEW-2871, 5-[4-Phenyl-5-(trifluoromethyl)-2-thienyl]-3-[3-(trifluoromethyl)phenyl]- 1,2,4-oxadiazole;5-[4-Phenyl-5-(trifluoromethyl)thien-2-yl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole
73 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • AHH
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
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  • Chemenu
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Package
  • 10
  • 2mg
  • 1mg
  • 50
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 1mlx10mM(inDMSO)
  • 0.5g
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mM*1mLinDMSO(Solution)
  • Manufactureraablocks
  • Product numberAA00BDPS
  • Product descriptionSew2871 98%
  • Packaging1mg
  • Price$28
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00BDPS
  • Product descriptionSew2871 ≥98%
  • Packaging5mg
  • Price$36
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00BDPS
  • Product descriptionSew2871 ≥98%
  • Packaging10mg
  • Price$68
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00BDPS
  • Product descriptionSew2871 ≥98%
  • Packaging25mg
  • Price$153
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00BDPS
  • Product descriptionSew2871 ≥98%
  • Packaging50mg
  • Price$288
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00BDPS
  • Product descriptionSew2871 98%
  • Packaging100mg
  • Price$435
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY230575
  • Product descriptionSEW2871 98%
  • Packaging25MG
  • Price$305
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY230575
  • Product descriptionSEW2871 98%
  • Packaging100MG
  • Price$800
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY230575
  • Product descriptionSEW2871 98%
  • Packaging10MG
  • Price$140
  • Updated2026-05-27
  • Buy
  • ManufacturerAHH
  • Product numberMT-21378
  • Product description5-[4-Phenyl-5-(trifluoromethyl)-2-thienyl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole 97%
  • Packaging0.5g
  • Price$478
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-21378
  • Product description5-[4-Phenyl-5-(trifluoromethyl)-2-thienyl]-3-[3-(trifluoromethyl) phenyl]-1,2,4-oxadiazole 97%
  • Packaging0.5g
  • Price$478
  • Updated2026-05-25
  • Buy
  • ManufacturerAHH
  • Product numberMT-21378
  • Product description5-[4-Phenyl-5-(trifluoromethyl)-2-thienyl]-3-[3-(trifluoromethyl) phenyl]-1,2,4-oxadiazole 97%
  • Packaging0.5g
  • Price$478
  • Updated2026-05-26
  • Buy
  • ManufacturerAK Scientific
  • Product number1445AH
  • Product description5-[4-Phenyl-5-(trifluoromethyl)-2-thienyl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole
  • Packaging25mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1445AH
  • Product description5-[4-Phenyl-5-(trifluoromethyl)-2-thienyl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole
  • Packaging5mg
  • Price$82
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA656270
  • Product descriptionSEW2871 95+%
  • Packaging5mg
  • Price$76
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA656270
  • Product descriptionSEW2871 95+%
  • Packaging10mg
  • Price$123
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00BDPS Sew2871 98% 1mg $28 2026-05-28 Buy
aablocks AA00BDPS Sew2871 ≥98% 5mg $36 2026-05-28 Buy
aablocks AA00BDPS Sew2871 ≥98% 10mg $68 2026-05-28 Buy
aablocks AA00BDPS Sew2871 ≥98% 25mg $153 2026-05-28 Buy
aablocks AA00BDPS Sew2871 ≥98% 50mg $288 2026-05-28 Buy
aablocks AA00BDPS Sew2871 98% 100mg $435 2026-05-28 Buy
ACHEMBLOCK Y230575 SEW2871 98% 25MG $305 2026-05-27 Buy
ACHEMBLOCK Y230575 SEW2871 98% 100MG $800 2026-05-27 Buy
ACHEMBLOCK Y230575 SEW2871 98% 10MG $140 2026-05-27 Buy
AHH MT-21378 5-[4-Phenyl-5-(trifluoromethyl)-2-thienyl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole 97% 0.5g $478 2021-12-16 Buy
AHH MT-21378 5-[4-Phenyl-5-(trifluoromethyl)-2-thienyl]-3-[3-(trifluoromethyl) phenyl]-1,2,4-oxadiazole 97% 0.5g $478 2026-05-25 Buy
AHH MT-21378 5-[4-Phenyl-5-(trifluoromethyl)-2-thienyl]-3-[3-(trifluoromethyl) phenyl]-1,2,4-oxadiazole 97% 0.5g $478 2026-05-26 Buy
AK Scientific 1445AH 5-[4-Phenyl-5-(trifluoromethyl)-2-thienyl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole 25mg $200 2021-12-16 Buy
AK Scientific 1445AH 5-[4-Phenyl-5-(trifluoromethyl)-2-thienyl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole 5mg $82 2021-12-16 Buy
Ambeed A656270 SEW2871 95+% 5mg $76 2021-12-16 Buy
Ambeed A656270 SEW2871 95+% 10mg $123 2021-12-16 Buy

Properties

Melting point :94.5-95.3 °C
Boiling point :490.3±55.0 °C(Predicted)
Density :1.415±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 17 mg/mL
form :solid
pka :-3.48±0.43(Predicted)
color :white
InChI :1S/C20H10F6N2OS/c21-19(22,23)13-8-4-7-12(9-13)17-27-18(29-28-17)15-10-14(11-5-2-1-3-6-11)16(30-15)20(24,25)26/h1-10H
InChIKey :OYMNPJXKQVTQTR-UHFFFAOYSA-N
SMILES :FC(F)(F)c1cccc(c1)-c2noc(n2)-c3cc(-c4ccccc4)c(s3)C(F)(F)F

Safety Information

Symbol(GHS): Skull and Crossbones (GHS06)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

SEW2871 is a small molecule selective agonist of EDG-1 (Sphingosine-1-phosphate receptor 1; S1P1), a protein involved in signaling and regulation of heart rate, coronary artery caliber, and lymphocyte recirculation. SEW2871 has been used as a tool for investigating the role of the EDG-1 receptor in cardiovascular regulation, and specifically for its role in ischemia/reperfusion injury. An antiinflammatory behavior is produced by SEW2871 activation of the EDG-1 receptor, showing an inhibition of monocyte adhesion to endothelial cells upon this activation.

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