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ChemicalBook >> CAS DataBase List >> 1,3-BIS(4-HYDROXYPHENYL)-4-METHYL-5-[4-(2-PIPERIDINYLETHOXY)PHENOL]-1H-PYRAZOLE DIHYDROCHLORIDE

1,3-BIS(4-HYDROXYPHENYL)-4-METHYL-5-[4-(2-PIPERIDINYLETHOXY)PHENOL]-1H-PYRAZOLE DIHYDROCHLORIDE

1,3-BIS(4-HYDROXYPHENYL)-4-METHYL-5-[4-(2-PIPERIDINYLETHOXY)PHENOL]-1H-PYRAZOLE DIHYDROCHLORIDE price.
  • $81 - $782
  • Product name: 1,3-BIS(4-HYDROXYPHENYL)-4-METHYL-5-[4-(2-PIPERIDINYLETHOXY)PHENOL]-1H-PYRAZOLE DIHYDROCHLORIDE
  • CAS: 289726-02-9
  • MF: C29H31N3O3
  • MW: 469.57
  • EINECS:
  • MDL Number:MFCD06411603
  • Synonyms:METHYL-PIPERIDINO-PYRAZOLE DIHYDROCHLORIDE;1,3-BIS(4-HYDROXYPHENYL)-4-METHYL-5-[4-(2-PIPERIDINYLETHOXY)PHENOL]-1H-PYRAZOLE DIHYDROCHLORIDE;MPP DIHYDROCHLORIDE;MMP DIHYDROCHLORIDE;MPP2HCl;Methyl-piperidino-pyrazole, 1,3-Bis(4-hydroxyphenyl)-4-methyl-5-[4-(2-piperidinylethoxy)phenol]-1H-pyrazole dihydrochloride;Methylpiperidino pyrazole;TXLGPGWHIIHRHH-UHFFFAOYSA-N
Price7 Properties Safety Information Description
7 prices
Selected condition：
Brand
  • ApexBio Technology
  • Cayman Chemical
  • Tocris
  • TRC
Package
  • 50
  • 5mg
  • 10mg
  • 10
  • 50mg
  • ManufacturerApexBio Technology
  • Product numberC3089
  • Product descriptionMethylpiperidinopyrazole
  • Packaging10mg
  • Price$172
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13863
  • Product descriptionMethylpiperidino pyrazole ≥98%
  • Packaging5mg
  • Price$81
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13863
  • Product descriptionMethylpiperidino pyrazole ≥98%
  • Packaging10mg
  • Price$152
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13863
  • Product descriptionMethylpiperidino pyrazole ≥98%
  • Packaging50mg
  • Price$632
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number1991
  • Product descriptionMPPdihydrochloride ≥98%(HPLC)
  • Packaging10
  • Price$186
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number1991
  • Product descriptionMPPdihydrochloride ≥98%(HPLC)
  • Packaging50
  • Price$782
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberM745835
  • Product descriptionMPP
  • Packaging10mg
  • Price$520
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ApexBio Technology C3089 Methylpiperidinopyrazole 10mg $172 2021-12-16 Buy
Cayman Chemical 13863 Methylpiperidino pyrazole ≥98% 5mg $81 2024-03-01 Buy
Cayman Chemical 13863 Methylpiperidino pyrazole ≥98% 10mg $152 2024-03-01 Buy
Cayman Chemical 13863 Methylpiperidino pyrazole ≥98% 50mg $632 2024-03-01 Buy
Tocris 1991 MPPdihydrochloride ≥98%(HPLC) 10 $186 2021-12-16 Buy
Tocris 1991 MPPdihydrochloride ≥98%(HPLC) 50 $782 2021-12-16 Buy
TRC M745835 MPP 10mg $520 2021-12-16 Buy

Properties

Boiling point :659.2±55.0 °C(Predicted)
Density :1.22±0.1 g/cm3(Predicted)
storage temp. :Desiccate at +4°C
solubility :DMSO: ≥5 mg/mL, soluble
form :solid
pka :8.80±0.15(Predicted)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Estrogen action is mediated through two estrogen receptor (ER) subtypes, ERα and ERβ, which have distinct target tissue distributions and functional activities. Methylpiperidino pyrazole is an ER antagonist that is highly selective for ERα compared to ERβ (Kis = 5.6 nM and 2.3 μM, respectively). It can inhibit ERα transcriptional activation with an IC50 value of 80 nM. It has been used to evaluate the role of ERα in various estrogen-responsive systems, including certain cancers.

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Suppliers and manufacturers

TargetMol Chemicals Inc. 3B Pharmachem (Wuhan) International Co.,Ltd. ShangHai Caerulum Pharma Discovery Co., Ltd. EMMX Biotechnology LLC Shanghai QianYan Bio-technology Co., Ltd Shanghai Chaolan Chemical Technology Center BOC Sciences Suzhou Derivative Biotechnology Co., Ltd. ChemeGen(Shanghai) Biotechnology Co.,Ltd. Suzhou Chenrui Biotechnology Co. LTD