1-(4-METHOXYBENZYL)-4-OXO-1,4-DIHYDRO-3-QUINOLINECARBOXYLIC ACID
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- $36 - $5120
- Product name: 1-(4-METHOXYBENZYL)-4-OXO-1,4-DIHYDRO-3-QUINOLINECARBOXYLIC ACID
- CAS: 338747-41-4
- MF: C18H15NO4
- MW: 309.32
- EINECS:
- MDL Number:MFCD01315710
- Synonyms:1-(4-METHOXYBENZYL)-4-OXO-1,4-DIHYDRO-3-QUINOLINECARBOXYLIC ACID;1-(4-Methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid;Benzyl quinolone carboxylic acid;BQCA;3-Quinolinecarboxylic acid, 1,4-dihydro-1-[(4-methoxyphenyl)methyl]-4-oxo-;1-(4-Methoxybenzyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic ...;mAChR,Muscarinic acetylcholine receptor,Inhibitor,inhibit,BQCA;BQCA, 10 mM in DMSO
57 prices
Selected condition：
Brand
- aablocks
- AccelPharmtech
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
Package
- 10mg
- 50
- 5mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 1G
- 5G
- 25G
- Manufactureraablocks
- Product numberAA00D4SQ
- Product descriptionBQCA ≥98%(HPLC)
- Packaging10mg
- Price$36
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00D4SQ
- Product descriptionBQCA
- Packaging25mg
- Price$84
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00D4SQ
- Product descriptionBQCA
- Packaging50mg
- Price$139
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00D4SQ
- Product descriptionBQCA
- Packaging100mg
- Price$236
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00D4SQ
- Product descriptionBQCA
- Packaging200mg
- Price$337
- Updated2026-05-28
- Buy
- ManufacturerAccelPharmtech
- Product numberC1630
- Product description1-(4-methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylicacid 97.00%
- Packaging1G
- Price$2370
- Updated2021-12-16
- Buy
- ManufacturerAccelPharmtech
- Product numberC1630
- Product description1-(4-methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 97.00%
- Packaging1G
- Price$2370
- Updated2026-05-21
- Buy
- ManufacturerAccelPharmtech
- Product numberC1630
- Product description1-(4-methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylicacid 97.00%
- Packaging5G
- Price$2750
- Updated2021-12-16
- Buy
- ManufacturerAccelPharmtech
- Product numberC1630
- Product description1-(4-methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 97.00%
- Packaging5G
- Price$2750
- Updated2026-05-21
- Buy
- ManufacturerAccelPharmtech
- Product numberC1630
- Product description1-(4-methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylicacid 97.00%
- Packaging25G
- Price$5120
- Updated2021-12-16
- Buy
- ManufacturerAccelPharmtech
- Product numberC1630
- Product description1-(4-methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 97.00%
- Packaging25G
- Price$5120
- Updated2026-05-21
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65701
- Product description1-(4-methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 98%
- Packaging1G
- Price$405
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65701
- Product description1-(4-methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 98%
- Packaging100MG
- Price$130
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number3996AB
- Product description1-(4-Methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylicacid
- Packaging10mg
- Price$153
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3996AB
- Product description1-(4-Methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylicacid
- Packaging5mg
- Price$119
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0155574
- Product description1-(4-METHOXYBENZYL)-4-OXO-1,4-DIHYDRO-3-QUINOLINECARBOXYLIC ACID 95.00%
- Packaging5G
- Price$4966.5
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00D4SQ | BQCA ≥98%(HPLC) | 10mg | $36 | 2026-05-28 | Buy |
| aablocks | AA00D4SQ | BQCA | 25mg | $84 | 2026-05-28 | Buy |
| aablocks | AA00D4SQ | BQCA | 50mg | $139 | 2026-05-28 | Buy |
| aablocks | AA00D4SQ | BQCA | 100mg | $236 | 2026-05-28 | Buy |
| aablocks | AA00D4SQ | BQCA | 200mg | $337 | 2026-05-28 | Buy |
| AccelPharmtech | C1630 | 1-(4-methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylicacid 97.00% | 1G | $2370 | 2021-12-16 | Buy |
| AccelPharmtech | C1630 | 1-(4-methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 97.00% | 1G | $2370 | 2026-05-21 | Buy |
| AccelPharmtech | C1630 | 1-(4-methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylicacid 97.00% | 5G | $2750 | 2021-12-16 | Buy |
| AccelPharmtech | C1630 | 1-(4-methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 97.00% | 5G | $2750 | 2026-05-21 | Buy |
| AccelPharmtech | C1630 | 1-(4-methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylicacid 97.00% | 25G | $5120 | 2021-12-16 | Buy |
| AccelPharmtech | C1630 | 1-(4-methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 97.00% | 25G | $5120 | 2026-05-21 | Buy |
| ACHEMBLOCK | Q65701 | 1-(4-methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 98% | 1G | $405 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q65701 | 1-(4-methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 98% | 100MG | $130 | 2026-05-27 | Buy |
| AK Scientific | 3996AB | 1-(4-Methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylicacid | 10mg | $153 | 2021-12-16 | Buy |
| AK Scientific | 3996AB | 1-(4-Methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylicacid | 5mg | $119 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0155574 | 1-(4-METHOXYBENZYL)-4-OXO-1,4-DIHYDRO-3-QUINOLINECARBOXYLIC ACID 95.00% | 5G | $4966.5 | 2021-12-16 | Buy |
Properties
Melting point :210-212 °C
Boiling point :492.6±45.0 °C(Predicted)
Density :1.346±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL (clear solution)
pka :0.70±0.20(Predicted)
form :powder
color :white to beige
InChI :1S/C18H15NO4/c1-23-13-8-6-12(7-9-13)10-19-11-15(18(21)22)17(20)14-4-2-3-5-16(14)19/h2-9,11H,10H2,1H3,(H,21,22)
InChIKey :BZBBTGCKPRSPGF-UHFFFAOYSA-N
SMILES :COc1ccc(CN2C=C(C(O)=O)C(=O)c3ccccc23)cc1
Boiling point :492.6±45.0 °C(Predicted)
Density :1.346±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL (clear solution)
pka :0.70±0.20(Predicted)
form :powder
color :white to beige
InChI :1S/C18H15NO4/c1-23-13-8-6-12(7-9-13)10-19-11-15(18(21)22)17(20)14-4-2-3-5-16(14)19/h2-9,11H,10H2,1H3,(H,21,22)
InChIKey :BZBBTGCKPRSPGF-UHFFFAOYSA-N
SMILES :COc1ccc(CN2C=C(C(O)=O)C(=O)c3ccccc23)cc1
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | ||||||||||||||
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Description
BQCA is a highly selective positive allosteric modulator of the M1 muscarinic acetylcholine receptor (mAChR), as it dose-dependently reduces the concentration of acetylcholine required to activate the M1 receptor. The effective range for potentiation of M1 in cells by BQCA is 0.1 to 100 μM with an inflection point value of 845 nM when 3 nM acetylcholine is used. BQCA displays no potentiation, agonism, or antagonism at other mAChRs at concentrations up to 100 μM. It has excellent brain penetration and increases the firing rate of medial prefrontal cortex neurons in vivo in rats. BQCA prevents scopolamine-induced memory deficits in both contextual fear conditioning and a spontaneous alternation task in mice. It also restores impairment in reversal learning in a mouse model of Alzheimer’s disease and improves memory performance in rats.More related product prices
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