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ChemicalBook >> CAS DataBase List >> 13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2

13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2

13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2 price.
  • $77 - $602
  • Product name: 13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2
  • CAS: 363-23-5
  • MF: C20H32O5
  • MW: 352.47
  • EINECS:
  • MDL Number:MFCD00135217
  • Synonyms:9,15-DIOXO-11ALPHA-HYDROXY-PROST-5Z-EN-1-OIC ACID;15-keto-13,14-dihydroprostaglandine2 ;13,14-dihydro-15-oxo-prostaglandin E2;13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2;(E)-7-[(1R,2R,3R)-3-hydroxy-5-oxo-2-(3-oxooctyl)cyclopentyl]hept-5-enoic acid;13,14-Dihydro-15-keto-PGE2;13,14-Dihydro-15-ketoprostaglandinE2 solution;(5Z)-11α-Hydroxy-9,15-dioxoprosta-5-ene-1-oic acid
4 prices
Selected condition:
Brand
  • Cayman Chemical
Package
  • 100μg
  • 1mg
  • 5mg
  • 10mg
  • ManufacturerCayman Chemical
  • Product number14650
  • Product description13,14-dihydro-15-keto Prostaglandin E2 ≥95%
  • Packaging1mg
  • Price$77
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10007214
  • Product description13,14-dihydro-15-keto Prostaglandin E2 MaxSpec? Standard >95%
  • Packaging100μg
  • Price$118
  • Updated2023-06-20
  • Buy
  • ManufacturerCayman Chemical
  • Product number14650
  • Product description13,14-dihydro-15-keto Prostaglandin E2 ≥95%
  • Packaging5mg
  • Price$340
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14650
  • Product description13,14-dihydro-15-keto Prostaglandin E2 ≥95%
  • Packaging10mg
  • Price$602
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 14650 13,14-dihydro-15-keto Prostaglandin E2 ≥95% 1mg $77 2024-03-01 Buy
Cayman Chemical 10007214 13,14-dihydro-15-keto Prostaglandin E2 MaxSpec? Standard >95% 100μg $118 2023-06-20 Buy
Cayman Chemical 14650 13,14-dihydro-15-keto Prostaglandin E2 ≥95% 5mg $340 2024-03-01 Buy
Cayman Chemical 14650 13,14-dihydro-15-keto Prostaglandin E2 ≥95% 10mg $602 2024-03-01 Buy

Properties

Boiling point :538.1±45.0 °C(Predicted)
Density :1.086±0.06 g/cm3(Predicted)
storage temp. :−20°C
pka :4.75±0.10(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning GHS hazard pictograms P280,P302+P352, P312, P322, P363,P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

13,14-dihydro-15-keto Prostaglandin E2 (13,14-dihydro-15-keto PGE2) is the primary metabolite of PGE2 in plasma. Endogenous or infused PGE2 is rapidly metabolized by the enzymes 15-hydroxy PGDH and 15-oxo-PG Δ13-reductase to form 13,14-dihydro-15-keto PGE2. 13,14-dihydro-15-keto PGE2 accumulates to detectable levels; plasma levels in humans are between 10-100 pg/ml. It undergoes further metabolism and chemical decomposition, giving it a relatively short half-life. In dogs, the plasma half-life of 13,14-dihydro-15-keto PGE2 is about 9 minutes.3 In humans the metabolite has a similar short half-life, making it a poor choice of analytes for assays designed to measure total PGE2 biosynthesis.

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