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ChemicalBook >> CAS DataBase List >> 9-(BETA-D-ARABINOFURANOSYL)GUANINE

9-(BETA-D-ARABINOFURANOSYL)GUANINE

9-(BETA-D-ARABINOFURANOSYL)GUANINE price.
  • $17 - $1260
  • Product name: 9-(BETA-D-ARABINOFURANOSYL)GUANINE
  • CAS: 38819-10-2
  • MF: C10H13N5O5
  • MW: 283.24
  • EINECS:
  • MDL Number:MFCD00065486
  • Synonyms:9-beta-D-Arabinofuranosylguanine Hydrate;2-AMino-9-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one;Arabinoguanosine;Araguanosine;ara-Guanosine;Guanine arabinoside;9-β-D-Arabinofuranosyl guanine hydrate;9-&beta
33 prices
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Brand
  • AHH
  • AK Scientific
  • American Custom Chemicals Corporation
  • Apolloscientific
  • Arctom
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • Chem-Impex
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
Package
  • 5MG
  • 10MG
  • 25MG
  • 50mg
  • 0.1g
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • 5g
  • 10g
  • ManufacturerAHH
  • Product numberMT-46254
  • Product description9-(beta-D-Arabinofuranosyl)guanine 98%
  • Packaging0.1g
  • Price$260
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number5032AB
  • Product description9-b-D-Arabinofuranosylguanine
  • Packaging1g
  • Price$333
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberNUC0000484
  • Product description9-BETA-D-ARABINOFURANOSYLGUANINE 95.00%
  • Packaging5MG
  • Price$675.65
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberNUC0000484
  • Product description9-BETA-D-ARABINOFURANOSYLGUANINE 95.00%
  • Packaging25MG
  • Price$942.31
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIMN2040
  • Product descriptionArabinofuranosyl-guanine
  • Packaging250mg
  • Price$111
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIMN2040
  • Product descriptionArabinofuranosyl-guanine
  • Packaging1g
  • Price$238
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS019155
  • Product description9-beta-Arabinosylguanine ≥99%
  • Packaging25mg
  • Price$17
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS019155
  • Product description9-beta-Arabinosylguanine ≥99%
  • Packaging50mg
  • Price$23
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS019155
  • Product description9-beta-Arabinosylguanine ≥99%
  • Packaging250mg
  • Price$111
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS019155
  • Product description9-beta-Arabinosylguanine ≥99%
  • Packaging1g
  • Price$291
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS019155
  • Product description9-beta-Arabinosylguanine ≥99%
  • Packaging5g
  • Price$962
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberNA06002
  • Product description9-(b-D-Arabinofuranosyl)guanine
  • Packaging100mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberNA06002
  • Product description9-(b-D-Arabinofuranosyl)guanine
  • Packaging500mg
  • Price$135
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number27984
  • Product descriptionAra-G
  • Packaging50mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27984
  • Product descriptionAra-G
  • Packaging100mg
  • Price$61
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27984
  • Product descriptionAra-G
  • Packaging250mg
  • Price$116
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-46254 9-(beta-D-Arabinofuranosyl)guanine 98% 0.1g $260 2021-12-16 Buy
AK Scientific 5032AB 9-b-D-Arabinofuranosylguanine 1g $333 2021-12-16 Buy
American Custom Chemicals Corporation NUC0000484 9-BETA-D-ARABINOFURANOSYLGUANINE 95.00% 5MG $675.65 2021-12-16 Buy
American Custom Chemicals Corporation NUC0000484 9-BETA-D-ARABINOFURANOSYLGUANINE 95.00% 25MG $942.31 2021-12-16 Buy
Apolloscientific BIMN2040 Arabinofuranosyl-guanine 250mg $111 2021-12-16 Buy
Apolloscientific BIMN2040 Arabinofuranosyl-guanine 1g $238 2021-12-16 Buy
Arctom AS019155 9-beta-Arabinosylguanine ≥99% 25mg $17 2021-12-16 Buy
Arctom AS019155 9-beta-Arabinosylguanine ≥99% 50mg $23 2021-12-16 Buy
Arctom AS019155 9-beta-Arabinosylguanine ≥99% 250mg $111 2021-12-16 Buy
Arctom AS019155 9-beta-Arabinosylguanine ≥99% 1g $291 2021-12-16 Buy
Arctom AS019155 9-beta-Arabinosylguanine ≥99% 5g $962 2021-12-16 Buy
Biosynth Carbosynth NA06002 9-(b-D-Arabinofuranosyl)guanine 100mg $50 2021-12-16 Buy
Biosynth Carbosynth NA06002 9-(b-D-Arabinofuranosyl)guanine 500mg $135 2021-12-16 Buy
Cayman Chemical 27984 Ara-G 50mg $32 2024-03-01 Buy
Cayman Chemical 27984 Ara-G 100mg $61 2024-03-01 Buy
Cayman Chemical 27984 Ara-G 250mg $116 2024-03-01 Buy

Properties

Melting point :225°C(lit.)
Density :2.25±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO: >10mg/mL
pka :9?+-.0.20(Predicted)
form :solid
color :White to Off-White
λmax :252nm(lit.)
InChIKey :NYHBQMYGNKIUIF-FJFJXFQQSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Ara-G (9-β-D-Arabinofuranosyl guanine) is an inducer of apoptosis, inhibitor of DNA synthesis, an antimetabolite, and antineoplastic. Ara-G is converted by cellular kinases to the active 5'-triphosphate, Ara-GTP. Incorporation of Ara-GTP into DNA leads to inhibition of DNA synthesis and apoptosis. The cellular accumulation of Ara-GTP is indicative of the clinical response to treatment with nelarabine, the prodrug. The differential accumulation and consequent selective cytotoxicity of Ara-G in T cells has been postulated to be due to the higher accumulation and slower elimination of ara-GTP in these cells. Nelarabine was developed because of poor water solubility of Ara-G, but Ara-G is DMSO-soluble. Nelarabine is approved in the United States for the treatment of T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LBL).

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