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ChemicalBook >> CAS DataBase List >> 9-(BETA-D-ARABINOFURANOSYL)GUANINE

9-(BETA-D-ARABINOFURANOSYL)GUANINE

9-(BETA-D-ARABINOFURANOSYL)GUANINE price.
  • $17 - $2100
  • Product name: 9-(BETA-D-ARABINOFURANOSYL)GUANINE
  • CAS: 38819-10-2
  • MF: C10H13N5O5
  • MW: 283.24
  • EINECS:
  • MDL Number:MFCD00065486
  • Synonyms:9-beta-D-Arabinofuranosylguanine Hydrate;2-AMino-9-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one;Arabinoguanosine;Araguanosine;ara-Guanosine;Guanine arabinoside;9-β-D-Arabinofuranosyl guanine hydrate;9-&beta
79 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • AHH
  • AK Scientific
  • American Custom Chemicals Corporation
  • Apolloscientific
  • Arctom
  • Biosynth
  • Cayman Chemical
  • Chemenu
  • Chem-Impex
  • ChemScene
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Package
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  • 10g
  • 25.00g
  • 25g
  • Manufactureraablocks
  • Product numberAA0037UQ
  • Product description9-β-D-Arabinofuranosylguanine 98%
  • Packaging250mg
  • Price$18
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0037UQ
  • Product description9-β-D-Arabinofuranosylguanine 98%
  • Packaging1g
  • Price$42
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0037UQ
  • Product description9-β-D-Arabinofuranosylguanine 98%
  • Packaging25g
  • Price$813
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY231936
  • Product description2-amino-9-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one 98%
  • Packaging25G
  • Price$705
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY231936
  • Product description2-amino-9-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one 98%
  • Packaging5G
  • Price$185
  • Updated2026-05-27
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  • ManufacturerAHH
  • Product numberMT-46254
  • Product description9-(beta-D-Arabinofuranosyl)guanine 98%
  • Packaging0.1g
  • Price$260
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-46254
  • Product description9-(beta-D-Arabinofuranosyl)guanine 97%
  • Packaging0.1g
  • Price$260
  • Updated2026-05-25
  • Buy
  • ManufacturerAHH
  • Product numberMT-46254
  • Product description9-(beta-D-Arabinofuranosyl)guanine 97%
  • Packaging0.1g
  • Price$260
  • Updated2026-05-26
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  • ManufacturerAK Scientific
  • Product number5032AB
  • Product description9-b-D-Arabinofuranosylguanine
  • Packaging1g
  • Price$333
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberNUC0000484
  • Product description9-BETA-D-ARABINOFURANOSYLGUANINE 95.00%
  • Packaging5MG
  • Price$675.65
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberNUC0000484
  • Product description9-BETA-D-ARABINOFURANOSYLGUANINE 95.00%
  • Packaging25MG
  • Price$942.31
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberBIMN2040
  • Product descriptionArabinofuranosyl-guanine
  • Packaging1g
  • Price$238
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIMN2040
  • Product descriptionArabinofuranosyl-guanine
  • Packaging1g
  • Price$240
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIMN2040
  • Product descriptionArabinofuranosyl-guanine
  • Packaging250mg
  • Price$112
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIMN2040
  • Product descriptionArabinofuranosyl-guanine
  • Packaging250mg
  • Price$111
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS019155
  • Product description9-beta-Arabinosylguanine ≥99%
  • Packaging250mg
  • Price$111
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA0037UQ 9-β-D-Arabinofuranosylguanine 98% 250mg $18 2026-05-28 Buy
aablocks AA0037UQ 9-β-D-Arabinofuranosylguanine 98% 1g $42 2026-05-28 Buy
aablocks AA0037UQ 9-β-D-Arabinofuranosylguanine 98% 25g $813 2026-05-28 Buy
ACHEMBLOCK Y231936 2-amino-9-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one 98% 25G $705 2026-05-27 Buy
ACHEMBLOCK Y231936 2-amino-9-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one 98% 5G $185 2026-05-27 Buy
AHH MT-46254 9-(beta-D-Arabinofuranosyl)guanine 98% 0.1g $260 2021-12-16 Buy
AHH MT-46254 9-(beta-D-Arabinofuranosyl)guanine 97% 0.1g $260 2026-05-25 Buy
AHH MT-46254 9-(beta-D-Arabinofuranosyl)guanine 97% 0.1g $260 2026-05-26 Buy
AK Scientific 5032AB 9-b-D-Arabinofuranosylguanine 1g $333 2021-12-16 Buy
American Custom Chemicals Corporation NUC0000484 9-BETA-D-ARABINOFURANOSYLGUANINE 95.00% 5MG $675.65 2021-12-16 Buy
American Custom Chemicals Corporation NUC0000484 9-BETA-D-ARABINOFURANOSYLGUANINE 95.00% 25MG $942.31 2021-12-16 Buy
Apolloscientific BIMN2040 Arabinofuranosyl-guanine 1g $238 2021-12-16 Buy
Apolloscientific BIMN2040 Arabinofuranosyl-guanine 1g $240 2026-06-04 Buy
Apolloscientific BIMN2040 Arabinofuranosyl-guanine 250mg $112 2026-06-04 Buy
Apolloscientific BIMN2040 Arabinofuranosyl-guanine 250mg $111 2021-12-16 Buy
Arctom AS019155 9-beta-Arabinosylguanine ≥99% 250mg $111 2021-12-16 Buy

Properties

Melting point :225°C(lit.)
Density :2.25±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO: >10mg/mL
pka :9+-.0.20(Predicted)
form :solid
color :White to Off-White
λmax :252nm(lit.)
InChI :InChI=1/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6+,9-/s3
InChIKey :NYHBQMYGNKIUIF-FJFJXFQQSA-N
SMILES :O=C1NC(N)=NC2N([C@H]3[C@H]([C@H](O)[C@@H](CO)O3)O)C=NC1=2 |&1:8,9,10,12,r|

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Ara-G (9-β-D-Arabinofuranosyl guanine) is an inducer of apoptosis, inhibitor of DNA synthesis, an antimetabolite, and antineoplastic. Ara-G is converted by cellular kinases to the active 5'-triphosphate, Ara-GTP. Incorporation of Ara-GTP into DNA leads to inhibition of DNA synthesis and apoptosis. The cellular accumulation of Ara-GTP is indicative of the clinical response to treatment with nelarabine, the prodrug. The differential accumulation and consequent selective cytotoxicity of Ara-G in T cells has been postulated to be due to the higher accumulation and slower elimination of ara-GTP in these cells. Nelarabine was developed because of poor water solubility of Ara-G, but Ara-G is DMSO-soluble. Nelarabine is approved in the United States for the treatment of T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LBL).

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