9-(BETA-D-ARABINOFURANOSYL)GUANINE
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- $17 - $1260
- Product name: 9-(BETA-D-ARABINOFURANOSYL)GUANINE
- CAS: 38819-10-2
- MF: C10H13N5O5
- MW: 283.24
- EINECS:
- MDL Number:MFCD00065486
- Synonyms:9-beta-D-Arabinofuranosylguanine Hydrate;2-AMino-9-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one;Arabinoguanosine;Araguanosine;ara-Guanosine;Guanine arabinoside;9-β-D-Arabinofuranosyl guanine hydrate;9-&beta
33 prices
Selected condition：
Brand
- AHH
- AK Scientific
- American Custom Chemicals Corporation
- Apolloscientific
- Arctom
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- Chem-Impex
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- TRC
Package
- 5MG
- 10MG
- 25MG
- 50mg
- 0.1g
- 100mg
- 250mg
- 500mg
- 1g
- 5g
- 10g
- ManufacturerAHH
- Product numberMT-46254
- Product description9-(beta-D-Arabinofuranosyl)guanine 98%
- Packaging0.1g
- Price$260
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number5032AB
- Product description9-b-D-Arabinofuranosylguanine
- Packaging1g
- Price$333
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberNUC0000484
- Product description9-BETA-D-ARABINOFURANOSYLGUANINE 95.00%
- Packaging5MG
- Price$675.65
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberNUC0000484
- Product description9-BETA-D-ARABINOFURANOSYLGUANINE 95.00%
- Packaging25MG
- Price$942.31
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIMN2040
- Product descriptionArabinofuranosyl-guanine
- Packaging250mg
- Price$111
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIMN2040
- Product descriptionArabinofuranosyl-guanine
- Packaging1g
- Price$238
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS019155
- Product description9-beta-Arabinosylguanine ≥99%
- Packaging25mg
- Price$17
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS019155
- Product description9-beta-Arabinosylguanine ≥99%
- Packaging50mg
- Price$23
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS019155
- Product description9-beta-Arabinosylguanine ≥99%
- Packaging250mg
- Price$111
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS019155
- Product description9-beta-Arabinosylguanine ≥99%
- Packaging1g
- Price$291
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS019155
- Product description9-beta-Arabinosylguanine ≥99%
- Packaging5g
- Price$962
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberNA06002
- Product description9-(b-D-Arabinofuranosyl)guanine
- Packaging100mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberNA06002
- Product description9-(b-D-Arabinofuranosyl)guanine
- Packaging500mg
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number27984
- Product descriptionAra-G
- Packaging50mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27984
- Product descriptionAra-G
- Packaging100mg
- Price$61
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27984
- Product descriptionAra-G
- Packaging250mg
- Price$116
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AHH | MT-46254 | 9-(beta-D-Arabinofuranosyl)guanine 98% | 0.1g | $260 | 2021-12-16 | Buy |
| AK Scientific | 5032AB | 9-b-D-Arabinofuranosylguanine | 1g | $333 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | NUC0000484 | 9-BETA-D-ARABINOFURANOSYLGUANINE 95.00% | 5MG | $675.65 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | NUC0000484 | 9-BETA-D-ARABINOFURANOSYLGUANINE 95.00% | 25MG | $942.31 | 2021-12-16 | Buy |
| Apolloscientific | BIMN2040 | Arabinofuranosyl-guanine | 250mg | $111 | 2021-12-16 | Buy |
| Apolloscientific | BIMN2040 | Arabinofuranosyl-guanine | 1g | $238 | 2021-12-16 | Buy |
| Arctom | AS019155 | 9-beta-Arabinosylguanine ≥99% | 25mg | $17 | 2021-12-16 | Buy |
| Arctom | AS019155 | 9-beta-Arabinosylguanine ≥99% | 50mg | $23 | 2021-12-16 | Buy |
| Arctom | AS019155 | 9-beta-Arabinosylguanine ≥99% | 250mg | $111 | 2021-12-16 | Buy |
| Arctom | AS019155 | 9-beta-Arabinosylguanine ≥99% | 1g | $291 | 2021-12-16 | Buy |
| Arctom | AS019155 | 9-beta-Arabinosylguanine ≥99% | 5g | $962 | 2021-12-16 | Buy |
| Biosynth Carbosynth | NA06002 | 9-(b-D-Arabinofuranosyl)guanine | 100mg | $50 | 2021-12-16 | Buy |
| Biosynth Carbosynth | NA06002 | 9-(b-D-Arabinofuranosyl)guanine | 500mg | $135 | 2021-12-16 | Buy |
| Cayman Chemical | 27984 | Ara-G | 50mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 27984 | Ara-G | 100mg | $61 | 2024-03-01 | Buy |
| Cayman Chemical | 27984 | Ara-G | 250mg | $116 | 2024-03-01 | Buy |
Properties
Melting point :225°C(lit.)
Density :2.25±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO: >10mg/mL
pka :9+-.0.20(Predicted)
form :solid
color :White to Off-White
λmax :252nm(lit.)
InChI :InChI=1/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6+,9-/s3
InChIKey :NYHBQMYGNKIUIF-FJFJXFQQSA-N
SMILES :O=C1NC(N)=NC2N([C@H]3[C@H]([C@H](O)[C@@H](CO)O3)O)C=NC1=2 |&1:8,9,10,12,r|
Density :2.25±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO: >10mg/mL
pka :9+-.0.20(Predicted)
form :solid
color :White to Off-White
λmax :252nm(lit.)
InChI :InChI=1/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6+,9-/s3
InChIKey :NYHBQMYGNKIUIF-FJFJXFQQSA-N
SMILES :O=C1NC(N)=NC2N([C@H]3[C@H]([C@H](O)[C@@H](CO)O3)O)C=NC1=2 |&1:8,9,10,12,r|
Safety Information
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Description
Ara-G (9-β-D-Arabinofuranosyl guanine) is an inducer of apoptosis, inhibitor of DNA synthesis, an antimetabolite, and antineoplastic. Ara-G is converted by cellular kinases to the active 5'-triphosphate, Ara-GTP. Incorporation of Ara-GTP into DNA leads to inhibition of DNA synthesis and apoptosis. The cellular accumulation of Ara-GTP is indicative of the clinical response to treatment with nelarabine, the prodrug. The differential accumulation and consequent selective cytotoxicity of Ara-G in T cells has been postulated to be due to the higher accumulation and slower elimination of ara-GTP in these cells. Nelarabine was developed because of poor water solubility of Ara-G, but Ara-G is DMSO-soluble. Nelarabine is approved in the United States for the treatment of T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LBL).Related product price
- 1184-16-3
$7-1510 - 38819-10-2
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$75-787.5
