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ChemicalBook >> CAS DataBase List >> Trifluoperazine dihydrochloride

Trifluoperazine dihydrochloride

Trifluoperazine dihydrochloride price.
  • $25 - $12000
  • Product name: Trifluoperazine dihydrochloride
  • CAS: 440-17-5
  • MF: C21H26Cl2F3N3S
  • MW: 480.42
  • EINECS:207-123-0
  • MDL Number:MFCD00012656
  • Synonyms:LABOTEST-BB LT00452002;10-[3-(4-METHYL-1-PIPERAZINYL)PROPYL]-2-TRIFLUOROMETHYL-PHENOTHIAZINE DIHYDROCHLORIDE;10-[3-(4-METHYLPIPERAZIN-1-YL)PROPYL]-2-(TRIFLUOROMETHYL)-10H-PHENOTHIAZINE DIHYDROCHLORIDE;TRIFLUOPERAZINE 2HCL;TRIFLUOPERAZINE DIHYDROCHLORIDE;STELAZINE;STELAZINE DIHYDROCHLORIDE;10-(3-(4-methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)-phenothiazindihy
Price64 Properties Safety Information Description
64 prices
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  • aablocks
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  • 10mM*1mLinDMSO(Solution)
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  • EvaluationSample
  • 10mM(in1mLDMSO)
  • Manufactureraablocks
  • Product numberAA0072IK
  • Product description10H-Phenothiazine,10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, hydrochloride (1:2) ≥98%(HPLC)(T)
  • Packaging1g
  • Price$25
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0072IK
  • Product description10H-Phenothiazine,10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, hydrochloride (1:2) 95%
  • Packaging5g
  • Price$79
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0072IK
  • Product description10H-Phenothiazine,10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, hydrochloride (1:2) 95%
  • Packaging10g
  • Price$124
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0072IK
  • Product description10H-Phenothiazine,10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, hydrochloride (1:2) 95%
  • Packaging25g
  • Price$213
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberZ238189
  • Product descriptionTrifluoperazine dihydrochloride 98%
  • Packaging25G
  • Price$165
  • Updated2026-05-27
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  • ManufacturerAHH
  • Product numberMT-59871
  • Product descriptionTrifluoperazine dihydrochloride 97%
  • Packaging500g
  • Price$580
  • Updated2026-05-26
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  • ManufacturerAK Scientific
  • Product numberC366
  • Product descriptionTrifluroperazine dihydrochloride 98%(HPLC)
  • Packaging10g
  • Price$170
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberJ99715
  • Product descriptionTrifluroperazine dihydrochloride 95%
  • Packaging25g
  • Price$186
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberJ10697
  • Product descriptionTrifluroperazine dihydrochloride 99%(HPLC),powder
  • Packaging1g
  • Price$195
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberC366
  • Product descriptionTrifluroperazine dihydrochloride 98%(HPLC)
  • Packaging25g
  • Price$340
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ99715
  • Product descriptionTrifluroperazine dihydrochloride 95%
  • Packaging10g
  • Price$108
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberJ10697
  • Product descriptionTrifluroperazine dihydrochloride 99%(HPLC),powder
  • Packaging100mg
  • Price$98
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberC366
  • Product descriptionTrifluroperazine dihydrochloride 98%(HPLC)
  • Packaging5g
  • Price$99
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ99715
  • Product descriptionTrifluroperazine dihydrochloride 95%
  • Packaging1g
  • Price$32
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberC366
  • Product descriptionTrifluroperazine dihydrochloride 98%(HPLC)
  • Packaging1g
  • Price$35
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10697
  • Product descriptionTrifluroperazine dihydrochloride 99%(HPLC),powder
  • Packaging25mg
  • Price$42
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA0072IK 10H-Phenothiazine,10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, hydrochloride (1:2) ≥98%(HPLC)(T) 1g $25 2026-05-28 Buy
aablocks AA0072IK 10H-Phenothiazine,10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, hydrochloride (1:2) 95% 5g $79 2026-05-28 Buy
aablocks AA0072IK 10H-Phenothiazine,10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, hydrochloride (1:2) 95% 10g $124 2026-05-28 Buy
aablocks AA0072IK 10H-Phenothiazine,10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, hydrochloride (1:2) 95% 25g $213 2026-05-28 Buy
ACHEMBLOCK Z238189 Trifluoperazine dihydrochloride 98% 25G $165 2026-05-27 Buy
AHH MT-59871 Trifluoperazine dihydrochloride 97% 500g $580 2026-05-26 Buy
AK Scientific C366 Trifluroperazine dihydrochloride 98%(HPLC) 10g $170 2026-06-04 Buy
AK Scientific J99715 Trifluroperazine dihydrochloride 95% 25g $186 2026-06-04 Buy
AK Scientific J10697 Trifluroperazine dihydrochloride 99%(HPLC),powder 1g $195 2026-06-04 Buy
AK Scientific C366 Trifluroperazine dihydrochloride 98%(HPLC) 25g $340 2026-06-04 Buy
AK Scientific J99715 Trifluroperazine dihydrochloride 95% 10g $108 2026-06-04 Buy
AK Scientific J10697 Trifluroperazine dihydrochloride 99%(HPLC),powder 100mg $98 2026-06-04 Buy
AK Scientific C366 Trifluroperazine dihydrochloride 98%(HPLC) 5g $99 2026-06-04 Buy
AK Scientific J99715 Trifluroperazine dihydrochloride 95% 1g $32 2026-06-04 Buy
AK Scientific C366 Trifluroperazine dihydrochloride 98%(HPLC) 1g $35 2026-06-04 Buy
AK Scientific J10697 Trifluroperazine dihydrochloride 99%(HPLC),powder 25mg $42 2026-06-04 Buy
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Properties

Melting point :243 °C (dec.)(lit.)
Flash point :9℃
storage temp. :-20°C
solubility :ethanol: soluble5mg/mL
pka :pK1 3.9, pK2 8.1(at 25℃)
form :powder
color :white to off-white
Water Solubility :water: 50g/L, clear
λmax :312nm(MeOH)(lit.)
Merck :14,9680
BRN :3820024
Stability :Hygroscopic
InChI :1S/C21H24F3N3S.2ClH/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24;;/h2-3,5-8,15H,4,9-14H2,1H3;2*1H
InChIKey :BXDAOUXDMHXPDI-UHFFFAOYSA-N
SMILES :Cl[H].Cl[H].CN1CCN(CCCN2c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1
CAS DataBase Reference :440-17-5(CAS DataBase Reference)
EPA Substance Registry System :10H-Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, dihydrochloride (440-17-5)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)Health Hazard (GHS08)Environment (GHS09)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger P260, P264, P270, P314, P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning P273, P391, P501
Precautionary statements:
P201 Obtain special instructions before use.
P273 Avoid release to the environment.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Trifluoperazine (TFP) is a phenothiazine compound with anti-adrenergic and anti-dopaminergic actions typical of antipsychotic agents. It antagonizes adrenergic receptors, with selectivity for α1 over the α2 subtypes (Kis = 24, 653, 163, and 391 nM for α1A, α2A, α2B, and α2C, respectively). TFP binds with much higher affinity to the dopamine D2-like receptor (Kd = 0.96 nM) compared to the dopamine D4-like and the serotonin 5-HT2A receptors (Kds = 44 and 135 nM, respectively). Furthermore, TFP antagonizes calmodulin (CaM) and alters the calcium-binding properties of calsequestrin (CSQ). TFP has been shown to activate type-2 ryanodine receptors independently of its CaM and CSQ activity.

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Suppliers and manufacturers

J & K SCIENTIFIC LTD. 3B Pharmachem (Wuhan) International Co.,Ltd. TAIYUAN RHF CO.,LTD. TCI (Shanghai) Development Co., Ltd. Adamas Reagent, Ltd. Chemsky（shanghai）International Co.,Ltd. Jinan Trio PharmaTech Co., Ltd. Sichuan Kulinan Technology Co., Ltd RYSS TECH LTD Tianjin heowns Biochemical Technology Co., Ltd.