Welcome to chemicalbook!
China English Japan Germany
010-86108875
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
Structure Search
RFQ
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
My chemicalbook Sign in

Welcome back!

RFQ
skype
MY Account
Top
ChemicalBook >> CAS DataBase List >> ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate

ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate

ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate price.
  • $32 - $2120
  • Product name: ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate
  • CAS: 4450-98-0
  • MF: C14H15NO4
  • MW: 261.27
  • EINECS:
  • MDL Number:MFCD00179167
  • Synonyms:1-Ebpc;1H-Pyrrole-3-carboxylic acid, 2,5-dihydro-4-hydroxy-5-oxo-1-(phenylmethyl)-, ethyl ester;Nsc 229530;1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylic acid ethyl ester;1-Benzyl-4-bydroxy-5-oxo-3-pyrroline-3-carboxylic Acid Ethyl Ester;2,5-Dihydro-4-hydroxy-5-oxo-1-(phenylMethyl)-1H-pyrrole-3-carboxylic Acid Ethyl Ester;CP-10668;Aldose Reductase,inhibit,EBPC,Inhibitor
Price46 Properties Safety Information Description
46 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • Acints
  • Advanced Chemicals Intermediat
  • Advanced Chemicals Intermediatesced Chemicals Intermediates
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Cayman Chemical
  • ChemScene
  • CSNpharm
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10.00mg
  • 10mg
  • 25mg
  • 50.00mg
  • 50mg
  • 100mg
  • 250mg
  • Manufactureraablocks
  • Product numberAA003DX8
  • Product descriptionEBPC
  • Packaging5mg
  • Price$80
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003DX8
  • Product descriptionEBPC
  • Packaging10mg
  • Price$111
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003DX8
  • Product descriptionEBPC
  • Packaging25mg
  • Price$183
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003DX8
  • Product descriptionEBPC
  • Packaging50mg
  • Price$253
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003DX8
  • Product descriptionEBPC
  • Packaging100mg
  • Price$351
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003DX8
  • Product descriptionEBPC ≥98%
  • Packaging1mg
  • Price$36
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY227327
  • Product descriptionEBPC 95.00%
  • Packaging10MG
  • Price$135
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY227327
  • Product descriptionEBPC 95.00%
  • Packaging25MG
  • Price$240
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY227327
  • Product descriptionEBPC 95.00%
  • Packaging100MG
  • Price$495
  • Updated2026-05-27
  • Buy
  • ManufacturerAcints
  • Product numberWS-03L-002
  • Product description1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylicacidethylester 95%+
  • Packaging50mg
  • Price$253.75
  • Updated2021-12-16
  • Buy
  • ManufacturerAcints
  • Product numberWS-03L-002
  • Product description1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylicacidethylester 95%+
  • Packaging10mg
  • Price$58
  • Updated2021-12-16
  • Buy
  • ManufacturerAcints
  • Product numberWS-03L-002
  • Product description1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylic acid ethyl ester 95%+
  • Packaging10mg
  • Price$67.5
  • Updated2026-05-20
  • Buy
  • ManufacturerAcints
  • Product numberWS-03L-002
  • Product description1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylic acid ethyl ester 95%+
  • Packaging50mg
  • Price$295.65
  • Updated2026-05-20
  • Buy
  • ManufacturerAdvanced Chemicals Intermediat
  • Product numberWS-03L-002
  • Product description1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylic acid ethyl ester 95%+
  • Packaging10mg
  • Price$67.5
  • Updated2026-05-19
  • Buy
  • ManufacturerAdvanced Chemicals Intermediat
  • Product numberWS-03L-002
  • Product description1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylic acid ethyl ester 95%+
  • Packaging50mg
  • Price$295.65
  • Updated2026-05-19
  • Buy
  • ManufacturerAdvanced Chemicals Intermediatesced Chemicals Intermediates
  • Product numberWS-03L-002
  • Product description1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylicacidethylester 95%+
  • Packaging50mg
  • Price$253.75
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA003DX8 EBPC 5mg $80 2026-05-28 Buy
aablocks AA003DX8 EBPC 10mg $111 2026-05-28 Buy
aablocks AA003DX8 EBPC 25mg $183 2026-05-28 Buy
aablocks AA003DX8 EBPC 50mg $253 2026-05-28 Buy
aablocks AA003DX8 EBPC 100mg $351 2026-05-28 Buy
aablocks AA003DX8 EBPC ≥98% 1mg $36 2026-05-28 Buy
ACHEMBLOCK Y227327 EBPC 95.00% 10MG $135 2026-05-27 Buy
ACHEMBLOCK Y227327 EBPC 95.00% 25MG $240 2026-05-27 Buy
ACHEMBLOCK Y227327 EBPC 95.00% 100MG $495 2026-05-27 Buy
Acints WS-03L-002 1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylicacidethylester 95%+ 50mg $253.75 2021-12-16 Buy
Acints WS-03L-002 1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylicacidethylester 95%+ 10mg $58 2021-12-16 Buy
Acints WS-03L-002 1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylic acid ethyl ester 95%+ 10mg $67.5 2026-05-20 Buy
Acints WS-03L-002 1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylic acid ethyl ester 95%+ 50mg $295.65 2026-05-20 Buy
Advanced Chemicals Intermediat WS-03L-002 1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylic acid ethyl ester 95%+ 10mg $67.5 2026-05-19 Buy
Advanced Chemicals Intermediat WS-03L-002 1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylic acid ethyl ester 95%+ 50mg $295.65 2026-05-19 Buy
Advanced Chemicals Intermediatesced Chemicals Intermediates WS-03L-002 1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylicacidethylester 95%+ 50mg $253.75 2021-12-16 Buy
Next Last

Properties

Melting point :135-136 °C
Boiling point :479.8±45.0 °C(Predicted)
Density :1.340±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: ≥10mg/mL
form :white powder
pka :4.50±1.00(Predicted)
color :white
InChI :1S/C14H15NO4/c1-2-19-14(18)11-9-15(13(17)12(11)16)8-10-6-4-3-5-7-10/h3-7,16H,2,8-9H2,1H3
InChIKey :IGYRPDIWSYGHMY-UHFFFAOYSA-N
SMILES :CCOC(=O)C1=C(O)C(=O)N(Cc2ccccc2)C1

Safety Information

Symbol(GHS): Corrosion (GHS05)Exclamation Mark (GHS07)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The human aldose reductase AKR1B1 is considered the rate limiting enzyme of the polyol pathway responsible for the conversion of glucose into sorbitol. It also acts as a highly efficient PGF2α synthase in response to interleukin-1β. Increased aldose reductase expression has been associated with complications of diabetes and may contribute to reduced efficacy of certain chemotherapeutic drugs. EBPC is a potent, selective inhibitor of aldose reductase with an IC50 value of 47 nM in vitro. Through its regulation of glucose metabolism, EBPC has been used to improve the cytotoxic effects of the anticancer agents doxorubicin and cisplatin in HeLa cervical carcinoma cells. EBPC also inhibits prostaglandin F2α (PGF2α) and PGE2 production in human endometrial cells with an EC50 value of 10 μM.

More related product prices

6913-92-4 Ethyl 3-(benzylamino)propanoate

Related product price

Suppliers and manufacturers

TargetMol Chemicals Inc.
EBPC
$36.00
EBPC CAS:4450-98-0
BOC Sciences
Hangzhou MolCore BioPharmatech Co.,Ltd. J & K SCIENTIFIC LTD. Tetranov Biopharm Chemsky（shanghai）International Co.,Ltd. EMMX Biotechnology LLC Shanghai EFE Biological Technology Co., Ltd. Aikon International Limited MedBioPharmaceutical Technology Inc