Welcome to chemicalbook!
China English Japan Germany
400-158-6606
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
Structured search
Inquriy
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
My chemicalbook My chemicalbook

Welcome back!

RFQ
skype
MY Account
Top
ChemicalBook >> CAS DataBase List >> ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate

ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate

ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate price.
  • $32 - $2120
  • Product name: ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate
  • CAS: 4450-98-0
  • MF: C14H15NO4
  • MW: 261.27
  • EINECS:
  • MDL Number:MFCD00179167
  • Synonyms:1-Ebpc;1H-Pyrrole-3-carboxylic acid, 2,5-dihydro-4-hydroxy-5-oxo-1-(phenylmethyl)-, ethyl ester;Nsc 229530;1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylic acid ethyl ester;1-Benzyl-4-bydroxy-5-oxo-3-pyrroline-3-carboxylic Acid Ethyl Ester;2,5-Dihydro-4-hydroxy-5-oxo-1-(phenylMethyl)-1H-pyrrole-3-carboxylic Acid Ethyl Ester;CP-10668;Aldose Reductase,inhibit,EBPC,Inhibitor
Price20 Properties Safety Information Description
20 prices
Selected condition：
Brand
  • Acints
  • Advanced Chemicals Intermediatesced Chemicals Intermediates
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Cayman Chemical
  • CSNpharm
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
Package
  • 1MG
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100MG
  • 250mg
  • ManufacturerAcints
  • Product numberWS-03L-002
  • Product description1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylicacidethylester 95%+
  • Packaging10mg
  • Price$58
  • Updated2021-12-16
  • Buy
  • ManufacturerAcints
  • Product numberWS-03L-002
  • Product description1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylicacidethylester 95%+
  • Packaging50mg
  • Price$253.75
  • Updated2021-12-16
  • Buy
  • ManufacturerAdvanced Chemicals Intermediatesced Chemicals Intermediates
  • Product numberWS-03L-002
  • Product description1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylicacidethylester 95%+
  • Packaging50mg
  • Price$253.75
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3779AE
  • Product description1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylicacidethylester
  • Packaging250mg
  • Price$810
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0027395
  • Product descriptionEBPC 95.00%
  • Packaging1MG
  • Price$135.45
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0027395
  • Product descriptionEBPC 95.00%
  • Packaging10MG
  • Price$739.2
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0027395
  • Product descriptionEBPC 95.00%
  • Packaging100MG
  • Price$1871.1
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6333
  • Product descriptionEBPC
  • Packaging10mg
  • Price$219
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6333
  • Product descriptionEBPC
  • Packaging50mg
  • Price$896
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1204
  • Product descriptionEBPC 99%
  • Packaging50mg
  • Price$354.2
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14183
  • Product descriptionEBPC ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14183
  • Product descriptionEBPC ≥98%
  • Packaging5mg
  • Price$93
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14183
  • Product descriptionEBPC ≥98%
  • Packaging10mg
  • Price$139
  • Updated2024-03-01
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN13622
  • Product descriptionEBPC
  • Packaging100mg
  • Price$751
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number058760
  • Product description1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylic acid ethyl ester 95+%
  • Packaging10mg
  • Price$152
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number058760
  • Product description1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylic acid ethyl ester 95+%
  • Packaging50mg
  • Price$613
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Acints WS-03L-002 1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylicacidethylester 95%+ 10mg $58 2021-12-16 Buy
Acints WS-03L-002 1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylicacidethylester 95%+ 50mg $253.75 2021-12-16 Buy
Advanced Chemicals Intermediatesced Chemicals Intermediates WS-03L-002 1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylicacidethylester 95%+ 50mg $253.75 2021-12-16 Buy
AK Scientific 3779AE 1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylicacidethylester 250mg $810 2021-12-16 Buy
American Custom Chemicals Corporation API0027395 EBPC 95.00% 1MG $135.45 2021-12-16 Buy
American Custom Chemicals Corporation API0027395 EBPC 95.00% 10MG $739.2 2021-12-16 Buy
American Custom Chemicals Corporation API0027395 EBPC 95.00% 100MG $1871.1 2021-12-16 Buy
ApexBio Technology B6333 EBPC 10mg $219 2021-12-16 Buy
ApexBio Technology B6333 EBPC 50mg $896 2021-12-16 Buy
Axon Medchem Axon1204 EBPC 99% 50mg $354.2 2021-12-16 Buy
Cayman Chemical 14183 EBPC ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 14183 EBPC ≥98% 5mg $93 2024-03-01 Buy
Cayman Chemical 14183 EBPC ≥98% 10mg $139 2024-03-01 Buy
CSNpharm CSN13622 EBPC 100mg $751 2021-12-16 Buy
Matrix Scientific 058760 1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylic acid ethyl ester 95+% 10mg $152 2021-12-16 Buy
Matrix Scientific 058760 1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylic acid ethyl ester 95+% 50mg $613 2021-12-16 Buy
Next Last

Properties

Melting point :135-136 °C
Boiling point :479.8±45.0 °C(Predicted)
Density :1.340±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: ≥10mg/mL
form :white powder
pka :4.50±1.00(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The human aldose reductase AKR1B1 is considered the rate limiting enzyme of the polyol pathway responsible for the conversion of glucose into sorbitol. It also acts as a highly efficient PGF2α synthase in response to interleukin-1β. Increased aldose reductase expression has been associated with complications of diabetes and may contribute to reduced efficacy of certain chemotherapeutic drugs. EBPC is a potent, selective inhibitor of aldose reductase with an IC50 value of 47 nM in vitro. Through its regulation of glucose metabolism, EBPC has been used to improve the cytotoxic effects of the anticancer agents doxorubicin and cisplatin in HeLa cervical carcinoma cells. EBPC also inhibits prostaglandin F2α (PGF2α) and PGE2 production in human endometrial cells with an EC50 value of 10 μM.

More related product prices

6913-92-4 Ethyl 3-(benzylamino)propanoate

Related product price

Suppliers and manufacturers

TargetMol Chemicals Inc.
Hangzhou MolCore BioPharmatech Co.,Ltd. J & K SCIENTIFIC LTD. Tetranov Biopharm Chemsky（shanghai）International Co.,Ltd. EMMX Biotechnology LLC Shanghai EFE Biological Technology Co., Ltd. Aikon International Limited MedBioPharmaceutical Technology Inc Energy Chemical