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ChemicalBook >> CAS DataBase List >> 6-THIO-2'-DEOXYGUANOSINE

6-THIO-2'-DEOXYGUANOSINE

6-THIO-2'-DEOXYGUANOSINE price.
  • $32 - $1200
  • Product name: 6-THIO-2'-DEOXYGUANOSINE
  • CAS: 789-61-7
  • MF: C10H13N5O3S
  • MW: 283.31
  • EINECS:
  • MDL Number:MFCD00672275
  • Synonyms:2’-deoxy-6-thio-guanosin ;2’-deoxythioguanosine ;2-amino-9-(2-deoxy-beta-d-erythro-pentofuranosyl)-9h-purine-6(1h)-thion ;beta-2’-deoxythioguanosine ;beta-thioguaninedeoxyriboside ;nci-c01581 ;tgdr ;BETA-THIOGUANIDINEDEOXYRIBOSIDE
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Brand
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 1mg
  • 5MG
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberNUC0003338
  • Product descriptionBETA-THIOGUANINE DEOXYRIBOSIDE 95.00%
  • Packaging5MG
  • Price$497.04
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6009
  • Product description6-Thio-dG
  • Packaging5mg
  • Price$103
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6009
  • Product description6-Thio-dG
  • Packaging10mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6009
  • Product description6-Thio-dG
  • Packaging25mg
  • Price$331
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6009
  • Product description6-Thio-dG
  • Packaging50mg
  • Price$520
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberND08563
  • Product description2'-Deoxy-6-thioguanosine
  • Packaging10mg
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberND08563
  • Product description2'-Deoxy-6-thioguanosine
  • Packaging25mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberND08563
  • Product description2'-Deoxy-6-thioguanosine
  • Packaging50mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberND08563
  • Product description2'-Deoxy-6-thioguanosine
  • Packaging100mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberND08563
  • Product description2'-Deoxy-6-thioguanosine
  • Packaging250mg
  • Price$425
  • Updated2021-12-16
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  • ManufacturerCayman Chemical
  • Product number19154
  • Product description6-thio-2′-Deoxyguanosine ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19154
  • Product description6-thio-2′-Deoxyguanosine ≥98%
  • Packaging5mg
  • Price$93
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19154
  • Product description6-thio-2′-Deoxyguanosine ≥98%
  • Packaging10mg
  • Price$122
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19154
  • Product description6-thio-2′-Deoxyguanosine ≥98%
  • Packaging25mg
  • Price$290
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0014289
  • Product description6-Thio-2'-Deoxyguanosine ≥97.0%
  • Packaging5mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0014289
  • Product description6-Thio-2'-Deoxyguanosine ≥97.0%
  • Packaging10mg
  • Price$100
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation NUC0003338 BETA-THIOGUANINE DEOXYRIBOSIDE 95.00% 5MG $497.04 2021-12-16 Buy
ApexBio Technology B6009 6-Thio-dG 5mg $103 2021-12-16 Buy
ApexBio Technology B6009 6-Thio-dG 10mg $150 2021-12-16 Buy
ApexBio Technology B6009 6-Thio-dG 25mg $331 2021-12-16 Buy
ApexBio Technology B6009 6-Thio-dG 50mg $520 2021-12-16 Buy
Biosynth Carbosynth ND08563 2'-Deoxy-6-thioguanosine 10mg $55 2021-12-16 Buy
Biosynth Carbosynth ND08563 2'-Deoxy-6-thioguanosine 25mg $90 2021-12-16 Buy
Biosynth Carbosynth ND08563 2'-Deoxy-6-thioguanosine 50mg $150 2021-12-16 Buy
Biosynth Carbosynth ND08563 2'-Deoxy-6-thioguanosine 100mg $250 2021-12-16 Buy
Biosynth Carbosynth ND08563 2'-Deoxy-6-thioguanosine 250mg $425 2021-12-16 Buy
Cayman Chemical 19154 6-thio-2′-Deoxyguanosine ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 19154 6-thio-2′-Deoxyguanosine ≥98% 5mg $93 2024-03-01 Buy
Cayman Chemical 19154 6-thio-2′-Deoxyguanosine ≥98% 10mg $122 2024-03-01 Buy
Cayman Chemical 19154 6-thio-2′-Deoxyguanosine ≥98% 25mg $290 2024-03-01 Buy
ChemScene CS-0014289 6-Thio-2'-Deoxyguanosine ≥97.0% 5mg $70 2021-12-16 Buy
ChemScene CS-0014289 6-Thio-2'-Deoxyguanosine ≥97.0% 10mg $100 2021-12-16 Buy

Properties

Melting point :190-192 °C
Boiling point :709.1±70.0 °C(Predicted)
Density :2.02±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), DMF (Slightly), Methanol (Slightly, Heated), Water (Very Slightly)
form :Solid
pka :6.81±0.20(Predicted)
color :Yellow to Brown

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

6-thio-2′-Deoxyguanosine (6-thio-dG) is a nucleoside analog that is incorporated into de novo-synthesized telomeres by telomerase. This induces telomerase dysfunction resulting in telomeric DNA damage and rapid cell death. This process occurs in cells expressing telomerase but not in telomerase-negative cells. DNA containing 6-thio-dG inhibits the function of RNase H, preventing the cleavage of DNA-RNA heteroduplexes. In mouse xenograft studies using A549 lung cancer cells, 6-thio-dG causes a decrease in tumor growth rate associated with telomere dysfunction.

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