6-Thioguanine
- $5 - $1500
- Product name: 6-Thioguanine
- CAS: 154-42-7
- MF: C5H5N5S
- MW: 167.19
- EINECS:205-827-2
- MDL Number:MFCD00233553
- Synonyms:2-Amino-1,7(9)-dihydro-purine-6-thione;2-amino-6-mercaptopurine (50X)*gamma-irradiated C;2-amino-6-mercaptopurine crystalline;2-Amino-6-purinethiol (6-Thioguanine);2-AMINO-6-MERCAPTOPURINE (50X)GAMMA-IRRA DIATED CEL;Tioguanine(Thioguanine);6-Thioguanine,~97%;6-THIOGUANIDE
60 prices
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Brand
- AK Scientific
- Alfa Aesar
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Frontier Specialty Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- SynQuest Laboratories
- TCI Chemical
- Tocris
- Usbiological
Package
- 2.5mg
- 5MG
- 25mg
- 50mg
- 100mg
- 50
- 200mg
- 250mg
- 0.500g
- 500mg
- 1g
- 5g
- 25g
- 100G
- ManufacturerAK Scientific
- Product numberJ10163
- Product description6-Thioguanine
- Packaging100mg
- Price$39
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ10163
- Product description6-Thioguanine
- Packaging1g
- Price$68.8
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberB21280
- Product description6-Thioguanine, 98%
- Packaging1g
- Price$85.4
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberB21280
- Product description6-Thioguanine, 98%
- Packaging5g
- Price$298.65
- Updated2024-03-01
- Buy
- ManufacturerAmbeed
- Product numberA393548
- Product description6-Thioguanine 98+%
- Packaging25mg
- Price$5
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA393548
- Product description6-Thioguanine 98+%
- Packaging100mg
- Price$7
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA393548
- Product description6-Thioguanine 98+%
- Packaging250mg
- Price$12
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA393548
- Product description6-Thioguanine 98+%
- Packaging1g
- Price$27
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA393548
- Product description6-Thioguanine 98+%
- Packaging5g
- Price$97
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0015888
- Product description6-THIOGUANINE 95.00%
- Packaging5MG
- Price$512
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0015888
- Product description6-THIOGUANINE 95.00%
- Packaging1G
- Price$735.45
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0015888
- Product description6-THIOGUANINE 95.00%
- Packaging5G
- Price$846.8
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4176
- Product descriptionThioguanine
- Packaging50mg
- Price$40
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4176
- Product descriptionThioguanine
- Packaging500mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberOR4016
- Product description2-Amino-6-purinethiol
- Packaging1g
- Price$19
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberOR4016
- Product description2-Amino-6-purinethiol
- Packaging5g
- Price$56
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | J10163 | 6-Thioguanine | 100mg | $39 | 2021-12-16 | Buy |
AK Scientific | J10163 | 6-Thioguanine | 1g | $68.8 | 2021-12-16 | Buy |
Alfa Aesar | B21280 | 6-Thioguanine, 98% | 1g | $85.4 | 2024-03-01 | Buy |
Alfa Aesar | B21280 | 6-Thioguanine, 98% | 5g | $298.65 | 2024-03-01 | Buy |
Ambeed | A393548 | 6-Thioguanine 98+% | 25mg | $5 | 2021-12-16 | Buy |
Ambeed | A393548 | 6-Thioguanine 98+% | 100mg | $7 | 2021-12-16 | Buy |
Ambeed | A393548 | 6-Thioguanine 98+% | 250mg | $12 | 2021-12-16 | Buy |
Ambeed | A393548 | 6-Thioguanine 98+% | 1g | $27 | 2021-12-16 | Buy |
Ambeed | A393548 | 6-Thioguanine 98+% | 5g | $97 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0015888 | 6-THIOGUANINE 95.00% | 5MG | $512 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0015888 | 6-THIOGUANINE 95.00% | 1G | $735.45 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0015888 | 6-THIOGUANINE 95.00% | 5G | $846.8 | 2021-12-16 | Buy |
ApexBio Technology | A4176 | Thioguanine | 50mg | $40 | 2021-12-16 | Buy |
ApexBio Technology | A4176 | Thioguanine | 500mg | $70 | 2021-12-16 | Buy |
Apolloscientific | OR4016 | 2-Amino-6-purinethiol | 1g | $19 | 2021-12-16 | Buy |
Apolloscientific | OR4016 | 2-Amino-6-purinethiol | 5g | $56 | 2021-12-16 | Buy |
Properties
Melting point :≥300 °C(lit.)
Density :1.483 (estimate)
refractive index :1.5605 (estimate)
storage temp. :2-8°C
solubility :Practically insoluble in water and in ethanol (96%). It dissolves in dilute solutions of alkali hydroxides.
form :lyophilized powder
pka :pKa 8.22 (Uncertain)
Boiling point :555.4±42.0 °C(Predicted)
color :Yellow to green
Water Solubility :soluble
Merck :14,9337
BRN :157765
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMF may be stored at -20°C for up to 1 month.
CAS DataBase Reference :154-42-7(CAS DataBase Reference)
EPA Substance Registry System :Thioguanine (154-42-7)
Density :1.483 (estimate)
refractive index :1.5605 (estimate)
storage temp. :2-8°C
solubility :Practically insoluble in water and in ethanol (96%). It dissolves in dilute solutions of alkali hydroxides.
form :lyophilized powder
pka :pKa 8.22 (Uncertain)
Boiling point :555.4±42.0 °C(Predicted)
color :Yellow to green
Water Solubility :soluble
Merck :14,9337
BRN :157765
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMF may be stored at -20°C for up to 1 month.
CAS DataBase Reference :154-42-7(CAS DataBase Reference)
EPA Substance Registry System :Thioguanine (154-42-7)
Safety Information
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Signal word: | Danger | ||||||||||||||
Hazard statements: |
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Description
6-Thioguanine (6-TG) is a thio analog of the purine base guanine that incorporates into DNA during replication, inducing double-strand breaks that destabilize its structure and result in cytotoxicity. Upon incorporation into DNA, 6-TG has been shown to disrupt cytosine methylation by DNA methyltransferases, interfering with the epigenetic pathway of gene regulation. This compound has been used as a chemotherapeutic for acute leukemia and other types of cancer, including BRCA2-mutated tumors.More related product prices
1,9-DIHYDRO-6H-PURINE-6-THIONE 6-N-HEPTYLMERCAPTOPURINE 14443-37-9 6-METHYLMERCAPTOPURINE 342-69-8 2-MERCAPTOPURINE 6-METHYL-D3-MERCAPTOPURINE 2,6-Dithiopurine 1H-Imidazole-4-carboxylic acid 6-thioinosine 5'-monophosphate 6-THIOXANTHINE 6-MERCAPTOPURINE RIBOSIDE 6-ETHYLMERCAPTOPURINE 5856-48-4 67831-84-9 6-THIOGUANOSINERelated product price
- THIOGUANOSINE HYDRATE
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$50-2255 - 1,9-DIHYDRO-6H-PURINE-6-THIONE
$305
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