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ChemicalBook >> CAS DataBase List >> 4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE, 7-METHYL-2-(4-MORPHOLINYL)-9-[1-(PHENYLAMINO)ETHYL]-

4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE, 7-METHYL-2-(4-MORPHOLINYL)-9-[1-(PHENYLAMINO)ETHYL]-

4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE, 7-METHYL-2-(4-MORPHOLINYL)-9-[1-(PHENYLAMINO)ETHYL]- price.
  • $32 - $4966.5
  • Product name: 4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE, 7-METHYL-2-(4-MORPHOLINYL)-9-[1-(PHENYLAMINO)ETHYL]-
  • CAS: 663619-89-4
  • MF: C21H24N4O2
  • MW: 364.44
  • EINECS:
  • MDL Number:MFCD11113209
  • Synonyms:4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE, 7-METHYL-2-(4-MORPHOLINYL)-9-[1-(PHENYLAMINO)ETHYL]-;TGX 221;(+/-)-7-Methyl-2-(morpholin-4-yl)-9-(1-phenylaminoethyl)pyrido[1,2-a]pyrimidin-4-one;7-methyl-2-(4-morpholinyl)-9-[1-(phenylamino)ethyl]-4H-pyrido[1,2-a]pyrimidin-4-one;(+/-)-7-Methyl-2-(morpholin-4-yl)-9-(1-phenylaminoethyl)pyrido[1,2-a]pyrimidin-4-one TGX 221;TGX 221 (+/-)-7-Methyl-2-(morpholin-4-yl)-9-(1-phenylaminoethyl)pyrido[1,2-a]pyrimidin-4-one;PI 3-Kβ Inhibitor VI, TGX-221;CS-429
32 prices
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Brand
  • Adipogen Life Sciences
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Tocris
  • TRC
Package
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  • 1000mg
  • 5G
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1089-M100
  • Product descriptionTGX-221 ≥95%
  • Packaging100mg
  • Price$923
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA203716
  • Product descriptionTGX-221 98+%
  • Packaging1mg
  • Price$32
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA203716
  • Product descriptionTGX-221 98+%
  • Packaging5mg
  • Price$64
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA203716
  • Product descriptionTGX-221 98+%
  • Packaging10mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA203716
  • Product descriptionTGX-221 98+%
  • Packaging25mg
  • Price$178
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA203716
  • Product descriptionTGX-221 98+%
  • Packaging50mg
  • Price$235
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA203716
  • Product descriptionTGX-221 98+%
  • Packaging100mg
  • Price$306
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA203716
  • Product descriptionTGX-221 98+%
  • Packaging250mg
  • Price$613
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA203716
  • Product descriptionTGX-221 98+%
  • Packaging1g
  • Price$1532
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000252
  • Product descriptionTGX-221 95.00%
  • Packaging1MG
  • Price$732
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000252
  • Product descriptionTGX-221 95.00%
  • Packaging5G
  • Price$4966.5
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2681
  • Product descriptionTGX-221
  • Packaging100mg
  • Price$620
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60188
  • Product descriptionTGX-221
  • Packaging20mg
  • Price$358
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1417
  • Product descriptionTGX221 99%
  • Packaging25mg
  • Price$368.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181167
  • Product descriptionTGX221 >98%
  • Packaging100mg
  • Price$542.3
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181167
  • Product descriptionTGX221 >98%
  • Packaging250mg
  • Price$1060.8
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences SYN-1089-M100 TGX-221 ≥95% 100mg $923 2021-12-16 Buy
Ambeed A203716 TGX-221 98+% 1mg $32 2021-12-16 Buy
Ambeed A203716 TGX-221 98+% 5mg $64 2021-12-16 Buy
Ambeed A203716 TGX-221 98+% 10mg $110 2021-12-16 Buy
Ambeed A203716 TGX-221 98+% 25mg $178 2021-12-16 Buy
Ambeed A203716 TGX-221 98+% 50mg $235 2021-12-16 Buy
Ambeed A203716 TGX-221 98+% 100mg $306 2021-12-16 Buy
Ambeed A203716 TGX-221 98+% 250mg $613 2021-12-16 Buy
Ambeed A203716 TGX-221 98+% 1g $1532 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000252 TGX-221 95.00% 1MG $732 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000252 TGX-221 95.00% 5G $4966.5 2021-12-16 Buy
ApexBio Technology A2681 TGX-221 100mg $620 2021-12-16 Buy
Arctom CFN60188 TGX-221 20mg $358 2021-12-16 Buy
Axon Medchem Axon1417 TGX221 99% 25mg $368.5 2021-12-16 Buy
Biorbyt Ltd orb181167 TGX221 >98% 100mg $542.3 2021-12-16 Buy
Biorbyt Ltd orb181167 TGX221 >98% 250mg $1060.8 2021-12-16 Buy

Properties

Melting point :198-201oC
Boiling point :557.3±60.0 °C(Predicted)
Density :1.25±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, Refrigerator, under inert atmosphere
solubility :DMSO (Slightly), Methanol (Very Slightly)
pka :3.90±0.50(Predicted)
form :Pale yellow solid.
color :Off-White to Pale Yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

PI 3-Kβ Inhibitor VI, TGX-221 is a cell-permeable morpholino-pyrimidinone compound that acts as a reversible, ATP-competitive, selective, and highly potent inhibitor of PI 3-kinase β (IC50 = 0.005, 0.1, 5, and ≥3.5 M for -β, -δ, -α and -γ isoforms, respectively) with little activity against a panel of 15 commonly studied protein kinases even at concentrations as high as 10.0 M. PI 3-Kβ Inhibitor VI, TGX-221 is an excellent tool for studying p110b-dependent responses in cells in vitro.

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