CAL-101
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- $33 - $3603.6
- Product name: CAL-101
- CAS: 870281-82-6
- MF: C22H18FN7O
- MW: 415.42
- EINECS:807-438-9
- MDL Number:MFCD19443647
- Synonyms:CAL101,CAL-101;CAL-101;GS1101;CAL-101 (GS-1101);5-Fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)propyl]-4(3H)-quinazolinone;CAL-101 (Idelalisib, GS-1101);(S)-2-(1-((9H-Purin-6-yl)aMino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one;4(3H)-Quinazolinone, 5-fluoro-3-phenyl-2-[(1S)-1-(1H-purin-6-ylaMino)propyl]-
30 prices
Selected condition：
Brand
- Abosyn
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- DC Chemicals
- Labseeker
- Matrix Scientific
- TRC
Package
- 1MG
- 5mg
- 10mg
- 20mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- 5g
- 10g
- 50G
- ManufacturerAbosyn
- Product number61-10788
- Product description(S)-2-(1-((9H-Purin-6-yl)amino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one 95-98%
- Packaging1g
- Price$225
- Updated2021-12-16
- Buy
- ManufacturerAbosyn
- Product number61-10788
- Product description(S)-2-(1-((9H-Purin-6-yl)amino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one 95-98%
- Packaging5g
- Price$675
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5707
- Product descriptionCAL-101
- Packaging10mg
- Price$123
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5707
- Product descriptionCAL-101
- Packaging50mg
- Price$406
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0024413
- Product descriptionCAL-101 95.00%
- Packaging1MG
- Price$667.01
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0024413
- Product descriptionCAL-101 95.00%
- Packaging50G
- Price$3603.6
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3005
- Product descriptionCAL-101(Idelalisib,GS-1101)
- Packaging100mg
- Price$220
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60050
- Product descriptionIdelalisib(CAL-101) ≥98%
- Packaging20mg
- Price$218
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2170
- Product descriptionCAL101-Idelalisib 99%
- Packaging5mg
- Price$104.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146250
- Product descriptionIdelalisib (CAL-101,GS-1101) >99.5%,ee > 99%
- Packaging100mg
- Price$510
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146250
- Product descriptionIdelalisib (CAL-101,GS-1101) >99.5%,ee > 99%
- Packaging250mg
- Price$690.2
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146250
- Product descriptionIdelalisib (CAL-101,GS-1101) >99.5%,ee > 99%
- Packaging1g
- Price$1356.6
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFI29231
- Product descriptionIdelalisib
- Packaging10mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFI29231
- Product descriptionIdelalisib
- Packaging50mg
- Price$263
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15279
- Product descriptionCAL-101 ≥98%
- Packaging5mg
- Price$33
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15279
- Product descriptionCAL-101 ≥98%
- Packaging10mg
- Price$63
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Abosyn | 61-10788 | (S)-2-(1-((9H-Purin-6-yl)amino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one 95-98% | 1g | $225 | 2021-12-16 | Buy |
| Abosyn | 61-10788 | (S)-2-(1-((9H-Purin-6-yl)amino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one 95-98% | 5g | $675 | 2021-12-16 | Buy |
| AK Scientific | SYN5707 | CAL-101 | 10mg | $123 | 2021-12-16 | Buy |
| AK Scientific | SYN5707 | CAL-101 | 50mg | $406 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0024413 | CAL-101 95.00% | 1MG | $667.01 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0024413 | CAL-101 95.00% | 50G | $3603.6 | 2021-12-16 | Buy |
| ApexBio Technology | A3005 | CAL-101(Idelalisib,GS-1101) | 100mg | $220 | 2021-12-16 | Buy |
| Arctom | CFN60050 | Idelalisib(CAL-101) ≥98% | 20mg | $218 | 2021-12-16 | Buy |
| Axon Medchem | Axon2170 | CAL101-Idelalisib 99% | 5mg | $104.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146250 | Idelalisib (CAL-101,GS-1101) >99.5%,ee > 99% | 100mg | $510 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146250 | Idelalisib (CAL-101,GS-1101) >99.5%,ee > 99% | 250mg | $690.2 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146250 | Idelalisib (CAL-101,GS-1101) >99.5%,ee > 99% | 1g | $1356.6 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FI29231 | Idelalisib | 10mg | $75 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FI29231 | Idelalisib | 50mg | $263 | 2021-12-16 | Buy |
| Cayman Chemical | 15279 | CAL-101 ≥98% | 5mg | $33 | 2024-03-01 | Buy |
| Cayman Chemical | 15279 | CAL-101 ≥98% | 10mg | $63 | 2024-03-01 | Buy |
Properties
Melting point :250-252oC
Boiling point :733.4±70.0 °C(Predicted)
Density :1.47
storage temp. :-20°C
solubility :Soluble in DMSO (>25 mg/ml)
form :White solid.
pka :10.00±0.10(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Boiling point :733.4±70.0 °C(Predicted)
Density :1.47
storage temp. :-20°C
solubility :Soluble in DMSO (>25 mg/ml)
form :White solid.
pka :10.00±0.10(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
The phosphatidylinositol 3-kinase (PI3K) signaling pathway has central roles in cell growth, development, and survival. CAL-101 is a cell permeable inhibitor of the PI3K catalytic subunit p110δ (IC50 = 2.5 nM) that demonstrates 40- to 300-fold selectivity against other PI3K class I enzymes (IC50s = 820, 565, and 89 nM for p110α, β, and γ, respectively). At 1 μM it can block constitutive PI3K signaling in malignant B-cell lines and primary patient tumor cells, resulting in decreased phosphorylation of Akt and other downstream effectors, an increase in poly(ADP-ribose) polymerase, and apoptosis. It has also been shown to inhibit the chemotaxis of chronic lymphocytic leukemia cells and to downregulate the secretion of chemokines triggered by B-cell receptor signaling.More related product prices
Ibrutinib IPI 145 Pictilisib (GDC-0941) BKM120 (NVP-BKM120, Buparlisib) Bortezomib Everolimus 2-Fluoro-6-nitro-N-phenylbenzamide (S)-tert-butyl (1-(5-fluoro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)propyl)carbaMate BOC-ABU-OH (S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one 2-Amino-6-fluorobenzoic acid 405169-16-6 ARRY-334543 Momelotinib CO-1686Related product price
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