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ChemicalBook >> CAS DataBase List >> 7,8-Dihydroxycoumarin

7,8-Dihydroxycoumarin

7,8-Dihydroxycoumarin price.
  • $45 - $524
  • Product name: 7,8-Dihydroxycoumarin
  • CAS: 486-35-1
  • MF: C9H6O4
  • MW: 178.14
  • EINECS:207-632-8
  • MDL Number:MFCD00016977
  • Synonyms:DAPHNETIN(P);Daphenetin;7,8-DIHYDROXYCOUMARIN (DAPHNETIN);2H-1-Benzopyran-2-one, 4,8-dihydroxy-;Daphnetin,7,8-Dihydroxycoumarin;Daphnetol;7,8-dihydroxy-2H-benzopyr...;7,8-dihydroxy-2H-benzopyran-2-one
8 prices
Selected condition:

Brand

  • Cayman Chemical
  • Sigma-Aldrich
  • TCI Chemical

Package

  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 1g
  • 5g
  • ManufacturerCayman Chemical
  • Product number20826
  • Product descriptionDaphnetin ≥90%
  • Packaging10mg
  • Price$45
  • Updated2018-11-19
  • Buy
  • ManufacturerCayman Chemical
  • Product number20826
  • Product descriptionDaphnetin ≥90%
  • Packaging25mg
  • Price$107
  • Updated2018-11-19
  • Buy
  • ManufacturerCayman Chemical
  • Product number20826
  • Product descriptionDaphnetin ≥90%
  • Packaging50mg
  • Price$203
  • Updated2018-11-19
  • Buy
  • ManufacturerCayman Chemical
  • Product number20826
  • Product descriptionDaphnetin ≥90%
  • Packaging100mg
  • Price$360
  • Updated2018-11-19
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberD5564
  • Product description7,8-Dihydroxycoumarin ≥97%, powder
  • Packaging25mg
  • Price$332
  • Updated2018-11-13
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberD5564
  • Product description7,8-Dihydroxycoumarin ≥97%, powder
  • Packaging5mg
  • Price$86
  • Updated2018-11-13
  • Buy
  • ManufacturerTCI Chemical
  • Product numberD4001
  • Product descriptionDaphnetin >90.0%(HPLC)
  • Packaging1g
  • Price$150
  • Updated2018-11-22
  • Buy
  • ManufacturerTCI Chemical
  • Product numberD4001
  • Product descriptionDaphnetin >90.0%(HPLC)
  • Packaging5g
  • Price$524
  • Updated2018-11-22
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 20826 Daphnetin ≥90% 10mg $45 2018-11-19 Buy
Cayman Chemical 20826 Daphnetin ≥90% 25mg $107 2018-11-19 Buy
Cayman Chemical 20826 Daphnetin ≥90% 50mg $203 2018-11-19 Buy
Cayman Chemical 20826 Daphnetin ≥90% 100mg $360 2018-11-19 Buy
Sigma-Aldrich D5564 7,8-Dihydroxycoumarin ≥97%, powder 25mg $332 2018-11-13 Buy
Sigma-Aldrich D5564 7,8-Dihydroxycoumarin ≥97%, powder 5mg $86 2018-11-13 Buy
TCI Chemical D4001 Daphnetin >90.0%(HPLC) 1g $150 2018-11-22 Buy
TCI Chemical D4001 Daphnetin >90.0%(HPLC) 5g $524 2018-11-22 Buy

Properties

Melting point: :265-268°C (dec.)
Boiling point: :270.35°C (rough estimate)
Density  :1.3431 (rough estimate)
refractive index  :1.4500 (estimate)
form  :solid
Merck  :14,2817
CAS DataBase Reference :486-35-1(CAS DataBase Reference)

Safety Information

Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Daphnetin is a coumarin analog that acts as an inhibitor of several protein kinases. Inhibits EGFR kinase (IC50 = 7.67 μM), PKA (IC50 = 9.33 μM), and PKC (IC50 = 25 μM), in vitro. The inhibition of EGFR kinase by daphnetin was competitive to ATP and non-competitive to the peptide substrate. Also acts as a potent antioxidant and anti-malarial agent.

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