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ChemicalBook >> CAS DataBase List >> N-Boc-trans-4-Hydroxy-L-proline methyl ester

N-Boc-trans-4-Hydroxy-L-proline methyl ester

N-Boc-trans-4-Hydroxy-L-proline methyl ester price.
  • $5 - $2379.2
  • Product name: N-Boc-trans-4-Hydroxy-L-proline methyl ester
  • CAS: 74844-91-0
  • MF: C11H19NO5
  • MW: 245.27
  • EINECS:616-143-2
  • MDL Number:MFCD00076981
  • Synonyms:N-T-BOC-TRANS-4-HYDROXY-L-PROLINE METHYL ESTER;N-(TERT-BUTOXYCARBONYL)-TRANS-HYDROXYL-L-PROLINE METHYL ESTER;N-ALPHA-T-BUTOXYCARBONYL-L-HYDROXYPROLINE METHYL ESTER;N-BOC-TRANS-4-HYDROXYL-L-PROLINE METHYL ESTER;N-BOC-TRANS-4-HYDROXY-L-PROLINE METHYL ESTER;N-BOC-L-TRANS-4-HYDROXY-PROLINE METHYL ESTER;(2R,4R)-4-HYDROXY-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 2-METHYL ESTER;(2S,4R)-1-(TERT-BUTOXYCARBONYL)-2-CARBOMETHOXY-4-HYDROXYPYRROLIDINE
Price94 Properties Safety Information Description
94 prices
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Brand
  • aablocks
  • AccelPharmtech
  • Acrotein
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Anichem
  • Apolloscientific
  • Arctom
  • Biosynth
  • Chem-Impex
  • ChemPep
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  • Medical Isotopes, Inc.
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  • Manufactureraablocks
  • Product numberAA003SRG
  • Product description(2S,4R)-1-TERT-BUTYL 2-METHYL 4-HYDROXYPYRROLIDINE-1,2-DICARBOXYLATE 98%
  • Packaging50g
  • Price$7
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003SRG
  • Product description(2S,4R)-1-TERT-BUTYL 2-METHYL 4-HYDROXYPYRROLIDINE-1,2-DICARBOXYLATE 98%
  • Packaging100g
  • Price$10
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003SRG
  • Product description(2S,4R)-1-TERT-BUTYL 2-METHYL 4-HYDROXYPYRROLIDINE-1,2-DICARBOXYLATE 97%
  • Packaging25g
  • Price$5
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003SRG
  • Product description(2S,4R)-1-TERT-BUTYL 2-METHYL 4-HYDROXYPYRROLIDINE-1,2-DICARBOXYLATE 98%
  • Packaging250g
  • Price$21
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003SRG
  • Product description(2S,4R)-1-TERT-BUTYL 2-METHYL 4-HYDROXYPYRROLIDINE-1,2-DICARBOXYLATE 98%
  • Packaging500g
  • Price$34
  • Updated2026-05-28
  • Buy
  • ManufacturerAccelPharmtech
  • Product numberCF1018
  • Product description(2S,4R)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate 99%
  • Packaging500G
  • Price$250
  • Updated2026-05-21
  • Buy
  • ManufacturerAccelPharmtech
  • Product numberCF1018
  • Product description(2S,4R)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate 99%
  • Packaging1KG
  • Price$340
  • Updated2026-05-21
  • Buy
  • ManufacturerAcrotein
  • Product numbera-5440
  • Product descriptionBoc-trans-4-hydroxy-L-proline methyl ester 97%
  • Packaging250g
  • Price$168.85
  • Updated2026-05-25
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  • ManufacturerAcrotein
  • Product numbera-5440
  • Product descriptionBoc-trans-4-hydroxy-L-proline methyl ester 97%
  • Packaging100g
  • Price$84.51
  • Updated2026-05-25
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  • ManufacturerAcrotein
  • Product numbera-5440
  • Product descriptionBoc-trans-4-hydroxy-L-proline methyl ester 97%
  • Packaging25g
  • Price$28.6
  • Updated2026-05-25
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  • ManufacturerAK Scientific
  • Product numberB034
  • Product descriptionBoc-trans-4-Hydroxy-L-proline methyl ester 98%(GC)
  • Packaging25g
  • Price$30
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberJ91745
  • Product descriptionBoc-trans-4-Hydroxy-L-proline methyl ester 95%
  • Packaging25g
  • Price$23
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberB034
  • Product descriptionBoc-trans-4-Hydroxy-L-proline methyl ester 98%(GC)
  • Packaging5g
  • Price$18
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ91745
  • Product descriptionBoc-trans-4-Hydroxy-L-proline methyl ester 95%
  • Packaging5g
  • Price$13
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ91745
  • Product descriptionBoc-trans-4-Hydroxy-L-proline methyl ester 95%
  • Packaging100g
  • Price$52
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberB034
  • Product descriptionBoc-trans-4-Hydroxy-L-proline methyl ester 98%(GC)
  • Packaging100g
  • Price$71
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA003SRG (2S,4R)-1-TERT-BUTYL 2-METHYL 4-HYDROXYPYRROLIDINE-1,2-DICARBOXYLATE 98% 50g $7 2026-05-28 Buy
aablocks AA003SRG (2S,4R)-1-TERT-BUTYL 2-METHYL 4-HYDROXYPYRROLIDINE-1,2-DICARBOXYLATE 98% 100g $10 2026-05-28 Buy
aablocks AA003SRG (2S,4R)-1-TERT-BUTYL 2-METHYL 4-HYDROXYPYRROLIDINE-1,2-DICARBOXYLATE 97% 25g $5 2026-05-28 Buy
aablocks AA003SRG (2S,4R)-1-TERT-BUTYL 2-METHYL 4-HYDROXYPYRROLIDINE-1,2-DICARBOXYLATE 98% 250g $21 2026-05-28 Buy
aablocks AA003SRG (2S,4R)-1-TERT-BUTYL 2-METHYL 4-HYDROXYPYRROLIDINE-1,2-DICARBOXYLATE 98% 500g $34 2026-05-28 Buy
AccelPharmtech CF1018 (2S,4R)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate 99% 500G $250 2026-05-21 Buy
AccelPharmtech CF1018 (2S,4R)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate 99% 1KG $340 2026-05-21 Buy
Acrotein a-5440 Boc-trans-4-hydroxy-L-proline methyl ester 97% 250g $168.85 2026-05-25 Buy
Acrotein a-5440 Boc-trans-4-hydroxy-L-proline methyl ester 97% 100g $84.51 2026-05-25 Buy
Acrotein a-5440 Boc-trans-4-hydroxy-L-proline methyl ester 97% 25g $28.6 2026-05-25 Buy
AK Scientific B034 Boc-trans-4-Hydroxy-L-proline methyl ester 98%(GC) 25g $30 2026-06-04 Buy
AK Scientific J91745 Boc-trans-4-Hydroxy-L-proline methyl ester 95% 25g $23 2026-06-04 Buy
AK Scientific B034 Boc-trans-4-Hydroxy-L-proline methyl ester 98%(GC) 5g $18 2026-06-04 Buy
AK Scientific J91745 Boc-trans-4-Hydroxy-L-proline methyl ester 95% 5g $13 2026-06-04 Buy
AK Scientific J91745 Boc-trans-4-Hydroxy-L-proline methyl ester 95% 100g $52 2026-06-04 Buy
AK Scientific B034 Boc-trans-4-Hydroxy-L-proline methyl ester 98%(GC) 100g $71 2026-06-04 Buy
Next Last

Properties

Melting point :92-96 °C (lit.)
alpha :-65 º (c=1 CHCl3)
Boiling point :132°C/0.05mmHg(lit.)
Density :1.216±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :Soluble in chloroform, dichloromethane and ethyl acetate.
pka :14.27±0.40(Predicted)
form :Crystalline Powder
color :White to light beige
optical activity :[α]20/D -65°, c = 1% in chloroform
Major Application :peptide synthesis
InChI :InChI=1S/C11H19NO5/c1-11(2,3)17-10(15)12-6-7(13)5-8(12)9(14)16-4/h7-8,13H,5-6H2,1-4H3/t7-,8+/m1/s1
InChIKey :MZMNEDXVUJLQAF-SFYZADRCSA-N
SMILES :N1(C(OC(C)(C)C)=O)C[C@H](O)C[C@H]1C(OC)=O
LogP :0.813 at 25℃
CAS DataBase Reference :74844-91-0(CAS DataBase Reference)

Safety Information

Symbol(GHS): Corrosion (GHS05)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

Description

It is used in the synthesis of For-Met-Leu-Phe-OMe (fMLF-OMe) analogues based on Met residue replacement by 4-amino-proline scaffold.

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D-Pyrrolidine-2-carboxylic acid BOC-L-Proline Methylparaben Tribenuron methyl Methyl acrylate Kresoxim-methyl Methanol cis-4-Hydroxy-L-proline Methyl salicylate L-Hydroxyproline N-Boc-trans-4-amino-L-proline methyl ester hydrochloride N-Boc-trans-4-amino-L-proline methyl ester CHLOROPHOSPHONAZO III Boc-L-Hydroxyproline 74844-91-0

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Suppliers and manufacturers

Sci General Material & Chemical Ltd Nanjing Ally Chemical S&T Co., Ltd. Shanxi Bethlehem Pharm-Tech Co.,Ltd. Shanghai Chiral Chemicals Inc. Zepeptide Biotechnology (Shijiazhuang) Co., LTD Jiangsu Jitai Peptide Technology Co., Ltd. BTC Pharmaceutical CO. Ltd J & K SCIENTIFIC LTD. Meryer (Shanghai) Chemical Technology Co., Ltd. ITIC MEDCHEM(SUZHOU) CO.,LTD.