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ChemicalBook >> CAS DataBase List >> N2-Isobutyryl-2''-O-(tert-butyldimethylsilyl)-5''-O-(4,4''-dimethoxytrityl)-gu

N2-Isobutyryl-2''-O-(tert-butyldimethylsilyl)-5''-O-(4,4''-dimethoxytrityl)-gu

N2-Isobutyryl-2''-O-(tert-butyldimethylsilyl)-5''-O-(4,4''-dimethoxytrityl)-gu price.
  • $14 - $210583
  • Product name: N2-Isobutyryl-2''-O-(tert-butyldimethylsilyl)-5''-O-(4,4''-dimethoxytrityl)-gu
  • CAS: 81279-39-2
  • MF: C41H51N5O8Si
  • MW: 769.96
  • EINECS:2017-001-1
  • MDL Number:MFCD00080293
  • Synonyms:5'-O-DMT-2'-O-iBu-N-Bz-Guanosine;5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(tert-butyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)guanosine;5'-DMT-2'-TBDMS-iBu-rG;5'-O-[bis(4-Methoxyphenyl)phenylMethyl]-2'-O-[(1,1-diMethylethyl)diMethylsilyl]-N-(2-Methyl-1-oxopropyl)-Guanosine;N2-Isobutyryl-2''-O-(tert-butyldimethylsilyl)-5''-O-(4,4''-dimethoxytrityl)-gu;5'-O-DMT-N-isobutyryl-2'-O-TBDMS-guanosine;5-O-(4,4-Dimethoxytrityl)-2-O-(tertbutyldimethylsilyl)-N-isobutyryl-Guanosine;2'-O-(tert-Butyldimethylsilyl)-5'-O-DMT-N-isobutyryl-guanosine
Price64 Properties Safety Information Description
64 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Arctom
  • Ark Pharm
  • Biosynth
  • Chemenu
  • ChemScene
  • Crysdot
  • Synthonix
  • TRC
  • Usbiological
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  • Manufactureraablocks
  • Product numberAA005LBV
  • Product description5''-O-[Bis(4-methoxyphenyl)phenylmethyl]-2''-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)guanosine 95%
  • Packaging250mg
  • Price$16
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA005LBV
  • Product description5''-O-[Bis(4-methoxyphenyl)phenylmethyl]-2''-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)guanosine 95%
  • Packaging1g
  • Price$39
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA005LBV
  • Product description5''-O-[Bis(4-methoxyphenyl)phenylmethyl]-2''-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)guanosine 95%
  • Packaging5g
  • Price$134
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA005LBV
  • Product description5''-O-[Bis(4-methoxyphenyl)phenylmethyl]-2''-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)guanosine 95%
  • Packaging25g
  • Price$483
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberX203795
  • Product descriptionN-[9-[(2R,3R,4R,5R)-5-[[Bis(4-methoxyphenyl)(phenyl)methoxy]methyl]-3-[(tert-butyldimethylsilyl)oxy]-4-hydroxy-2-tetrahydrofuryl]-6-oxo-6,9-dihydro-1H-purin-2-yl]isobutyramide 95%
  • Packaging25G
  • Price$725
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberX203795
  • Product descriptionN-[9-[(2R,3R,4R,5R)-5-[[Bis(4-methoxyphenyl)(phenyl)methoxy]methyl]-3-[(tert-butyldimethylsilyl)oxy]-4-hydroxy-2-tetrahydrofuryl]-6-oxo-6,9-dihydro-1H-purin-2-yl]isobutyramide 95%
  • Packaging5G
  • Price$200
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number2622AC
  • Product description5'-O-DMT-2'-O-iBu-N-Bz-Guanosine
  • Packaging250mg
  • Price$103
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA112825
  • Product description5'-O-DMT-2'-O-iBu-N-Bz-Guanosine 95%
  • Packaging10g
  • Price$260
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA112825
  • Product description5'-O-DMT-2'-O-iBu-N-Bz-Guanosine 95%
  • Packaging5g
  • Price$260
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA112825
  • Product description5'-O-DMT-2'-O-iBu-N-Bz-Guanosine 95%
  • Packaging1g
  • Price$62
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberNUC0005200
  • Product description5'-O-DMT-2'-O-IBU-N-BZ-GUANOSINE 95.00%
  • Packaging250MG
  • Price$391.65
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberBD-A112825
  • Product description5'-O-DMT-2'-O-iBu-N-Bz-Guanosine 95%
  • Packaging25g
  • Price$434
  • Updated2026-05-25
  • Buy
  • ManufacturerArctom
  • Product numberBD-A112825
  • Product description5'-O-DMT-2'-O-iBu-N-Bz-Guanosine 95%
  • Packaging25g
  • Price$434
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberBD-A112825
  • Product description5'-O-DMT-2'-O-iBu-N-Bz-Guanosine 95%
  • Packaging100g
  • Price$1585
  • Updated2026-05-25
  • Buy
  • ManufacturerArctom
  • Product numberBD-A112825
  • Product description5'-O-DMT-2'-O-iBu-N-Bz-Guanosine 95%
  • Packaging100g
  • Price$1585
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-43059
  • Product description5'-O-DMT-2'-O-iBu-N-Bz-Guanosine 98.12%
  • Packaging1g
  • Price$64
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA005LBV 5''-O-[Bis(4-methoxyphenyl)phenylmethyl]-2''-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)guanosine 95% 250mg $16 2026-05-28 Buy
aablocks AA005LBV 5''-O-[Bis(4-methoxyphenyl)phenylmethyl]-2''-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)guanosine 95% 1g $39 2026-05-28 Buy
aablocks AA005LBV 5''-O-[Bis(4-methoxyphenyl)phenylmethyl]-2''-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)guanosine 95% 5g $134 2026-05-28 Buy
aablocks AA005LBV 5''-O-[Bis(4-methoxyphenyl)phenylmethyl]-2''-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)guanosine 95% 25g $483 2026-05-28 Buy
ACHEMBLOCK X203795 N-[9-[(2R,3R,4R,5R)-5-[[Bis(4-methoxyphenyl)(phenyl)methoxy]methyl]-3-[(tert-butyldimethylsilyl)oxy]-4-hydroxy-2-tetrahydrofuryl]-6-oxo-6,9-dihydro-1H-purin-2-yl]isobutyramide 95% 25G $725 2026-05-27 Buy
ACHEMBLOCK X203795 N-[9-[(2R,3R,4R,5R)-5-[[Bis(4-methoxyphenyl)(phenyl)methoxy]methyl]-3-[(tert-butyldimethylsilyl)oxy]-4-hydroxy-2-tetrahydrofuryl]-6-oxo-6,9-dihydro-1H-purin-2-yl]isobutyramide 95% 5G $200 2026-05-27 Buy
AK Scientific 2622AC 5'-O-DMT-2'-O-iBu-N-Bz-Guanosine 250mg $103 2021-12-16 Buy
Ambeed A112825 5'-O-DMT-2'-O-iBu-N-Bz-Guanosine 95% 10g $260 2021-12-16 Buy
Ambeed A112825 5'-O-DMT-2'-O-iBu-N-Bz-Guanosine 95% 5g $260 2021-12-16 Buy
Ambeed A112825 5'-O-DMT-2'-O-iBu-N-Bz-Guanosine 95% 1g $62 2021-12-16 Buy
American Custom Chemicals Corporation NUC0005200 5'-O-DMT-2'-O-IBU-N-BZ-GUANOSINE 95.00% 250MG $391.65 2021-12-16 Buy
Arctom BD-A112825 5'-O-DMT-2'-O-iBu-N-Bz-Guanosine 95% 25g $434 2026-05-25 Buy
Arctom BD-A112825 5'-O-DMT-2'-O-iBu-N-Bz-Guanosine 95% 25g $434 2026-05-26 Buy
Arctom BD-A112825 5'-O-DMT-2'-O-iBu-N-Bz-Guanosine 95% 100g $1585 2026-05-25 Buy
Arctom BD-A112825 5'-O-DMT-2'-O-iBu-N-Bz-Guanosine 95% 100g $1585 2026-05-26 Buy
Arctom HY-43059 5'-O-DMT-2'-O-iBu-N-Bz-Guanosine 98.12% 1g $64 2026-05-26 Buy
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Properties

Density :1.25
storage temp. :2-8°C
pka :9.16±0.20(Predicted)
form :Solid
color :White to light yellow
InChIKey :JMCNKJFOIJGYRG-HVXBIEPNNA-N
SMILES :O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C3=C(C(NC(=N3)NC(=O)C(C)C)=O)N=C2)[C@H](O[Si](C(C)(C)C)(C)C)[C@@H]1O |&1:25,27,44,53,r|

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

5''-O-DMT-2''-O-iBu-N-Bz-Guanosine (cas# 81279-39-2) is a nucleotide used in the preparation of 4''-C-methoxy-2''-deoxy-2''-fluoro modified ribonucleotides to improve metabolic stability and elicit efficient RNAi-mediated gene silencing.

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