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ChemicalBook >> CAS DataBase List >> BenzaMide, N-[3-[1,4-dihydro-1-Methyl-7-[(6-Methyl-3-pyridinyl)aMino]-2-oxopyriMido[4,5-d]pyriMidin-3(2H)-yl]-4-Methylphenyl]-3-(trifluoroMethyl)-

BenzaMide, N-[3-[1,4-dihydro-1-Methyl-7-[(6-Methyl-3-pyridinyl)aMino]-2-oxopyriMido[4,5-d]pyriMidin-3(2H)-yl]-4-Methylphenyl]-3-(trifluoroMethyl)-

BenzaMide, N-[3-[1,4-dihydro-1-Methyl-7-[(6-Methyl-3-pyridinyl)aMino]-2-oxopyriMido[4,5-d]pyriMidin-3(2H)-yl]-4-Methylphenyl]-3-(trifluoroMethyl)- price.
  • $32 - $1800
  • Product name: BenzaMide, N-[3-[1,4-dihydro-1-Methyl-7-[(6-Methyl-3-pyridinyl)aMino]-2-oxopyriMido[4,5-d]pyriMidin-3(2H)-yl]-4-Methylphenyl]-3-(trifluoroMethyl)-
  • CAS: 839706-07-9
  • MF: C28H24F3N7O2
  • MW: 547.53
  • EINECS:
  • MDL Number:MFCD18251569
  • Synonyms:BenzaMide, N-[3-[1,4-dihy...;GNF-7;N-(4-Methyl-3-(1-methyl-7-((6-methylpyridin-3-yl)amino)-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)phenyl)-3-(trifluoromethyl)benzamide;N-[3-[1,4-Dihydro-1-methyl-7-[(6-methyl-3-pyridinyl)amino]-2-oxopyrimido[4,5-d]pyrimidin-3(2H)-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;BenzaMide, N-[3-[1,4-dihydro-1-Methyl-7-[(6-Methyl-3-pyridinyl)aMino]-2-oxopyriMido[4,5-d]pyriMidin-3(2H)-yl]-4-Methylphenyl]-3-(trifluoroMethyl)-;N-[4-methyl-3-[1-methyl-7-[(6-methylpyridin-3-yl)amino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;GNF-7, >98%;CS-1945
Price23 Properties Safety Information Description
23 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Tocris
  • TRC
Package
  • 5MG
  • 10
  • 50
  • 1mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number8418CS
  • Product descriptionCID11478363
  • Packaging25mg
  • Price$606
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA472268
  • Product descriptionN-(4-Methyl-3-(1-methyl-7-((6-methylpyridin-3-yl)amino)-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)phenyl)-3-(trifluoromethyl)benzamide 98+%
  • Packaging10mg
  • Price$191
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA472268
  • Product descriptionN-(4-Methyl-3-(1-methyl-7-((6-methylpyridin-3-yl)amino)-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)phenyl)-3-(trifluoromethyl)benzamide 98+%
  • Packaging25mg
  • Price$401
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA472268
  • Product descriptionN-(4-Methyl-3-(1-methyl-7-((6-methylpyridin-3-yl)amino)-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)phenyl)-3-(trifluoromethyl)benzamide 98+%
  • Packaging100mg
  • Price$1122
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0004740
  • Product descriptionN-[3-[1,4-DIHYDRO-1-METHYL-7-[(6-METHYL-3-PYRIDINYL)AMINO]-2-OXOPYRIMIDO-[4,5-D]PYRIMIDIN-3(2H)-YL]4-BENZAMIDE 95.00%
  • Packaging5MG
  • Price$504.98
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6033
  • Product descriptionGNF-7
  • Packaging5mg
  • Price$105
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19918
  • Product descriptionGNF-7
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19918
  • Product descriptionGNF-7
  • Packaging5mg
  • Price$116
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19918
  • Product descriptionGNF-7
  • Packaging10mg
  • Price$214
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19918
  • Product descriptionGNF-7
  • Packaging25mg
  • Price$456
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5551
  • Product descriptionGNF-7 99.47%
  • Packaging5mg
  • Price$108
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5551
  • Product descriptionGNF-7 99.47%
  • Packaging10mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5551
  • Product descriptionGNF-7 99.47%
  • Packaging25mg
  • Price$360
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5551
  • Product descriptionGNF-7 99.47%
  • Packaging50mg
  • Price$648
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5551
  • Product descriptionGNF-7 99.47%
  • Packaging100mg
  • Price$1152
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000673
  • Product descriptionGNF-7 98+%
  • Packaging50mg
  • Price$346
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 8418CS CID11478363 25mg $606 2021-12-16 Buy
Ambeed A472268 N-(4-Methyl-3-(1-methyl-7-((6-methylpyridin-3-yl)amino)-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)phenyl)-3-(trifluoromethyl)benzamide 98+% 10mg $191 2021-12-16 Buy
Ambeed A472268 N-(4-Methyl-3-(1-methyl-7-((6-methylpyridin-3-yl)amino)-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)phenyl)-3-(trifluoromethyl)benzamide 98+% 25mg $401 2021-12-16 Buy
Ambeed A472268 N-(4-Methyl-3-(1-methyl-7-((6-methylpyridin-3-yl)amino)-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)phenyl)-3-(trifluoromethyl)benzamide 98+% 100mg $1122 2021-12-16 Buy
American Custom Chemicals Corporation INB0004740 N-[3-[1,4-DIHYDRO-1-METHYL-7-[(6-METHYL-3-PYRIDINYL)AMINO]-2-OXOPYRIMIDO-[4,5-D]PYRIMIDIN-3(2H)-YL]4-BENZAMIDE 95.00% 5MG $504.98 2021-12-16 Buy
ApexBio Technology B6033 GNF-7 5mg $105 2021-12-16 Buy
Cayman Chemical 19918 GNF-7 1mg $32 2024-03-01 Buy
Cayman Chemical 19918 GNF-7 5mg $116 2024-03-01 Buy
Cayman Chemical 19918 GNF-7 10mg $214 2024-03-01 Buy
Cayman Chemical 19918 GNF-7 25mg $456 2024-03-01 Buy
ChemScene CS-5551 GNF-7 99.47% 5mg $108 2021-12-16 Buy
ChemScene CS-5551 GNF-7 99.47% 10mg $180 2021-12-16 Buy
ChemScene CS-5551 GNF-7 99.47% 25mg $360 2021-12-16 Buy
ChemScene CS-5551 GNF-7 99.47% 50mg $648 2021-12-16 Buy
ChemScene CS-5551 GNF-7 99.47% 100mg $1152 2021-12-16 Buy
Crysdot CD31000673 GNF-7 98+% 50mg $346 2021-12-16 Buy
Next Last

Properties

Density :1.404±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in EtOH; insoluble in H2O; ≥5.48 mg/mL in DMSO
form :solid
pka :12.82±0.70(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

GNF 7 inhibits ras signaling, Ack1 and germinal center kinase (GCK). Also, it suppresses proliferation, and induces cell cycle arrest and apoptosis in leukemia cells harboring NRAS mutations. It is a COVID19-related research product.

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