2-(4-Methoxyphenyl)-α-2-piperidinyl-4-quinolinemethanol Dihydrochloride
|
- $40 - $1671
- Product name: 2-(4-Methoxyphenyl)-α-2-piperidinyl-4-quinolinemethanol Dihydrochloride
- CAS: 858474-14-3
- MF: C22H25ClN2O2
- MW: 384.9
- EINECS:
- MDL Number:MFCD22666390
- Synonyms:2-(P-METHOXYPHENYL)-Α-2-PIPERIDYL-4-QUINOLINEMETHANOL DIHYDROCHLORIDE;2-(4-Methoxyphenyl)-α-2-piperidinyl-4-quinolinemethanol Dihydrochloride;[2-(4-Methoxyphenyl)4-quinolinyl]-(piperidin-2-y)-methanol dihydrochloride;NSC23925;NSC-23925;4-Quinolinemethanol, 2-(4-methoxyphenyl)-α-2-piperidinyl-, hydrochloride;(2-(4-Methoxyphenyl)quinolin-4-yl)(piperidin-2-yl)methanol dihydrochloride;NSC23925 HCl
23 prices
Selected condition：
Brand
- aablocks
- AK Scientific
- Arctom
- Biosynth
- Cayman Chemical
- ChemScene
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- Manufactureraablocks
- Product numberAA00G53Y
- Product descriptionNSC 23925
- Packaging5mg
- Price$125
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00G53Y
- Product descriptionNSC 23925
- Packaging10mg
- Price$180
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00G53Y
- Product descriptionNSC 23925
- Packaging25mg
- Price$331
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00G53Y
- Product descriptionNSC 23925
- Packaging50mg
- Price$533
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00G53Y
- Product descriptionNSC 23925
- Packaging100mg
- Price$889
- Updated2026-05-28
- Buy
- ManufacturerAK Scientific
- Product numberSYN5211
- Product descriptionNSC-23925
- Packaging10mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-19626
- Product descriptionNSC23925 99.43%
- Packaging5mg
- Price$154
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-19626
- Product descriptionNSC23925 99.43%
- Packaging25mg
- Price$588
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-19626
- Product descriptionNSC23925 99.43%
- Packaging10mg
- Price$266
- Updated2026-05-26
- Buy
- ManufacturerBiosynth
- Product numberIJB47414
- Product descriptionNSC 23925
- Packaging50mg
- Price$1200.5
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberIJB47414
- Product descriptionNSC 23925
- Packaging100mg
- Price$1671
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberIJB47414
- Product descriptionNSC 23925
- Packaging25mg
- Price$750.25
- Updated2026-06-04
- Buy
- ManufacturerCayman Chemical
- Product number21947
- Product descriptionNSC 23925 ≥98%
- Packaging5mg
- Price$116
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number21947
- Product descriptionNSC 23925 ≥98%
- Packaging10mg
- Price$171
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number21947
- Product descriptionNSC 23925 ≥98%
- Packaging1mg
- Price$40
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number21947
- Product descriptionNSC 23925 ≥98%
- Packaging25mg
- Price$376
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00G53Y | NSC 23925 | 5mg | $125 | 2026-05-28 | Buy |
| aablocks | AA00G53Y | NSC 23925 | 10mg | $180 | 2026-05-28 | Buy |
| aablocks | AA00G53Y | NSC 23925 | 25mg | $331 | 2026-05-28 | Buy |
| aablocks | AA00G53Y | NSC 23925 | 50mg | $533 | 2026-05-28 | Buy |
| aablocks | AA00G53Y | NSC 23925 | 100mg | $889 | 2026-05-28 | Buy |
| AK Scientific | SYN5211 | NSC-23925 | 10mg | $150 | 2021-12-16 | Buy |
| Arctom | HY-19626 | NSC23925 99.43% | 5mg | $154 | 2026-05-26 | Buy |
| Arctom | HY-19626 | NSC23925 99.43% | 25mg | $588 | 2026-05-26 | Buy |
| Arctom | HY-19626 | NSC23925 99.43% | 10mg | $266 | 2026-05-26 | Buy |
| Biosynth | IJB47414 | NSC 23925 | 50mg | $1200.5 | 2026-06-04 | Buy |
| Biosynth | IJB47414 | NSC 23925 | 100mg | $1671 | 2026-06-04 | Buy |
| Biosynth | IJB47414 | NSC 23925 | 25mg | $750.25 | 2026-06-04 | Buy |
| Cayman Chemical | 21947 | NSC 23925 ≥98% | 5mg | $116 | 2026-04-30 | Buy |
| Cayman Chemical | 21947 | NSC 23925 ≥98% | 10mg | $171 | 2026-04-30 | Buy |
| Cayman Chemical | 21947 | NSC 23925 ≥98% | 1mg | $40 | 2026-04-30 | Buy |
| Cayman Chemical | 21947 | NSC 23925 ≥98% | 25mg | $376 | 2026-04-30 | Buy |
Properties
storage temp. :room temp
solubility :H2O: soluble5mg/mL (clear solution)
form :powder
color :white to beige
Water Solubility :H2O: 5mg/mL (clear solution)
InChI :1S/C22H24N2O2.2ClH/c1-26-16-11-9-15(10-12-16)21-14-18(17-6-2-3-7-19(17)24-21)22(25)20-8-4-5-13-23-20;;/h2-3,6-7,9-12,14,20,22-23,25H,4-5,8,13H2,1H3;2*1H
InChIKey :WGWOQHWZXLGPNG-UHFFFAOYSA-N
SMILES :Cl.Cl.COc1ccc(cc1)-c2cc(C(O)C3CCCCN3)c4ccccc4n2
solubility :H2O: soluble5mg/mL (clear solution)
form :powder
color :white to beige
Water Solubility :H2O: 5mg/mL (clear solution)
InChI :1S/C22H24N2O2.2ClH/c1-26-16-11-9-15(10-12-16)21-14-18(17-6-2-3-7-19(17)24-21)22(25)20-8-4-5-13-23-20;;/h2-3,6-7,9-12,14,20,22-23,25H,4-5,8,13H2,1H3;2*1H
InChIKey :WGWOQHWZXLGPNG-UHFFFAOYSA-N
SMILES :Cl.Cl.COc1ccc(cc1)-c2cc(C(O)C3CCCCN3)c4ccccc4n2
Safety Information
| Symbol(GHS): |
|
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Danger | ||||||||||||||
| Hazard statements: |
|
||||||||||||||
| Precautionary statements: |
|
Description
NSC 23925 is a non-substrate inhibitor of P-glycoprotein (P-gp). It selectively reverses multidrug resistance mediated by P-gp over resistance mediated by multidrug resistance-associated protein 1 (MRP1/ABCC1) or breast cancer resistance protein (BCRP/ABCG2). It resensitizes paclitaxel-resistant SKOV3TR and OVCAR-8TR cells to paclitaxel . NSC 23925 reverses P-gp efflux, increasing the intracellular accumulation of P-gp substrates, including calcein AM in multidrug-resistant SKOV3TR and OVCAR-8TR cells. It prevents paclitaxel-induced overexpression of the P-gp gene MDR1 and P-gp protein level increases in OVCAR-8 cells. It also prevents the development of paclitaxel-induced multidrug resistance in a SKOV3 mouse xenograft model when administered at a dose of 50 mg/kg per day in combination with paclitaxel.More related product prices
Propylamine Propylene oxide 4-PIPERIDINOL, PROPIONATE, HYDROCHLORIDE 2-Pyridinecarbothioamide, N-2-pyridinyl- SID 487795 NSC319726Related product price
-
Propylamine
$7.62-4543 -
Propylene oxide
$7.62-721 -
4-PIPERIDINOL, PROPIONATE, HYDROCHLORIDE
$186-1468.5