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ChemicalBook >> CAS DataBase List >> N-[2-(1H-Indol-3-yl)ethyl]-N'-(4-pyridinyl)-1,4-benzenediamine

N-[2-(1H-Indol-3-yl)ethyl]-N'-(4-pyridinyl)-1,4-benzenediamine

N-[2-(1H-Indol-3-yl)ethyl]-N'-(4-pyridinyl)-1,4-benzenediamine price.
  • $28 - $6480
  • Product name: N-[2-(1H-Indol-3-yl)ethyl]-N'-(4-pyridinyl)-1,4-benzenediamine
  • CAS: 881202-45-5
  • MF: C21H20N4
  • MW: 328.41
  • EINECS:200-256-5
  • MDL Number:MFCD16620518
  • Synonyms:JNJ 26854165;SerdeMetan;JNJ-26854165 (SerdeMetan);JNJ 26854165 N-[2-(1H-Indol-3-yl)ethyl]-N'-(4-pyridinyl)-1,4-benzenediamine;N-[2-(1H-Indol-3-yl)ethyl]-N'-(4-pyridinyl)-1,4-benzenediamine JNJ 26854165;JNJ-26854165, >=98%;N1-[2-(1H-indol-3-yl)ethyl]-N4-4-pyridinyl-1,4-Benzene diamine;Serdemetan(JNJ 26854165)
Price62 Properties Safety Information Description
62 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • TRC
Package
  • 10mM(in1mLDMSO)
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 2x5mg
  • 10mM(in 1mL DMSO)
  • 250.00mg
  • 250mg
  • 1000mg
  • 1.00g
  • 10mM*1mLinDMSO(Solution)
  • EvaluationSample
  • 1mg
  • 1unit
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100MG
  • 1G
  • Manufactureraablocks
  • Product numberAA008CAJ
  • Product descriptionN1-[2-(1H-Indol-3-yl)ethyl]-N4-4-pyridinyl-1,4-benzenediamine ≥98%
  • Packaging1mg
  • Price$41
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008CAJ
  • Product descriptionN1-[2-(1H-Indol-3-yl)ethyl]-N4-4-pyridinyl-1,4-benzenediamine
  • Packaging2mg
  • Price$52
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008CAJ
  • Product descriptionN1-[2-(1H-Indol-3-yl)ethyl]-N4-4-pyridinyl-1,4-benzenediamine ≥98%
  • Packaging5mg
  • Price$59
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008CAJ
  • Product descriptionN1-[2-(1H-Indol-3-yl)ethyl]-N4-4-pyridinyl-1,4-benzenediamine
  • Packaging10mg
  • Price$98
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008CAJ
  • Product descriptionN1-[2-(1H-Indol-3-yl)ethyl]-N4-4-pyridinyl-1,4-benzenediamine
  • Packaging25mg
  • Price$179
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008CAJ
  • Product descriptionN1-[2-(1H-Indol-3-yl)ethyl]-N4-4-pyridinyl-1,4-benzenediamine
  • Packaging50mg
  • Price$318
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberO33888
  • Product descriptionJNJ26854165 98%
  • Packaging100MG
  • Price$195
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberO33888
  • Product descriptionJNJ26854165 98%
  • Packaging25MG
  • Price$65
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberO33888
  • Product descriptionJNJ26854165 98%
  • Packaging5MG
  • Price$30
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberO33888
  • Product descriptionJNJ26854165 98%
  • Packaging1G
  • Price$935
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product numberX7539
  • Product descriptionSerdemetan
  • Packaging1g
  • Price$2273
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000886
  • Product descriptionJNJ-26854165 95.00%
  • Packaging1G
  • Price$6480
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000886
  • Product descriptionJNJ-26854165 95.00%
  • Packaging5MG
  • Price$462
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000886
  • Product descriptionJNJ-26854165 95.00%
  • Packaging10MG
  • Price$494
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000886
  • Product descriptionJNJ-26854165 95.00%
  • Packaging25MG
  • Price$580
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000886
  • Product descriptionJNJ-26854165 95.00%
  • Packaging50MG
  • Price$727
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA008CAJ N1-[2-(1H-Indol-3-yl)ethyl]-N4-4-pyridinyl-1,4-benzenediamine ≥98% 1mg $41 2026-05-28 Buy
aablocks AA008CAJ N1-[2-(1H-Indol-3-yl)ethyl]-N4-4-pyridinyl-1,4-benzenediamine 2mg $52 2026-05-28 Buy
aablocks AA008CAJ N1-[2-(1H-Indol-3-yl)ethyl]-N4-4-pyridinyl-1,4-benzenediamine ≥98% 5mg $59 2026-05-28 Buy
aablocks AA008CAJ N1-[2-(1H-Indol-3-yl)ethyl]-N4-4-pyridinyl-1,4-benzenediamine 10mg $98 2026-05-28 Buy
aablocks AA008CAJ N1-[2-(1H-Indol-3-yl)ethyl]-N4-4-pyridinyl-1,4-benzenediamine 25mg $179 2026-05-28 Buy
aablocks AA008CAJ N1-[2-(1H-Indol-3-yl)ethyl]-N4-4-pyridinyl-1,4-benzenediamine 50mg $318 2026-05-28 Buy
ACHEMBLOCK O33888 JNJ26854165 98% 100MG $195 2026-05-27 Buy
ACHEMBLOCK O33888 JNJ26854165 98% 25MG $65 2026-05-27 Buy
ACHEMBLOCK O33888 JNJ26854165 98% 5MG $30 2026-05-27 Buy
ACHEMBLOCK O33888 JNJ26854165 98% 1G $935 2026-05-27 Buy
AK Scientific X7539 Serdemetan 1g $2273 2021-12-16 Buy
American Custom Chemicals Corporation INB0000886 JNJ-26854165 95.00% 1G $6480 2021-12-16 Buy
American Custom Chemicals Corporation INB0000886 JNJ-26854165 95.00% 5MG $462 2021-12-16 Buy
American Custom Chemicals Corporation INB0000886 JNJ-26854165 95.00% 10MG $494 2021-12-16 Buy
American Custom Chemicals Corporation INB0000886 JNJ-26854165 95.00% 25MG $580 2021-12-16 Buy
American Custom Chemicals Corporation INB0000886 JNJ-26854165 95.00% 50MG $727 2021-12-16 Buy
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Properties

storage temp. :Store at -20°C
solubility :insoluble in EtOH; insoluble in H2O; ≥14.8 mg/mL in DMSO
form :solid
color :Light brown to brown
InChI :InChI=1S/C21H20N4/c1-2-4-21-20(3-1)16(15-24-21)9-14-23-17-5-7-18(8-6-17)25-19-10-12-22-13-11-19/h1-8,10-13,15,23-24H,9,14H2,(H,22,25)
InChIKey :CEGSUKYESLWKJP-UHFFFAOYSA-N
SMILES :C1(NCCC2C3=C(NC=2)C=CC=C3)=CC=C(NC2C=CN=CC=2)C=C1

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The E3 ubiquitin ligase known as murine double minute 2 (MDM2; HDM2 in humans) binds to and then ubiquitinates several proteins, most notably the tumor suppressor p53. JNJ-26854165 is an antagonist of MDM2 that suppresses the growth of cancer cell lines expressing wild-type p53 (IC50 values range from 240-440 nM). It induces p53-mediated transcription culminating in apoptotic death of acute leukemia cells. JNJ-26854165 is orally bioavailable and has anti-proliferative as well as apoptotic actions in various tumor models. As MDM2 interacts with and modulates several targets in addition to p53, JNJ-26854165 affects multiple signaling pathways.

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Suppliers and manufacturers

Shanghai JiYi Biotechnology Co. Ltd. Shanghai Boyle Chemical Co., Ltd. Chembest Research Laboratories Limited VDM Biochemicals Jinan Trio PharmaTech Co., Ltd. Dalian Meilun Biotech Co., Ltd. Shanghai civi chemical technology co.,Ltd Shanghai Topbiochem Technology Co., Ltd NCE Biomedical Co.,Ltd. Haoyuan Chemexpress Co., Ltd.