15-keto-17-phenyl trinor Prostaglandin F2α

$64 - $650
Product name: 15-keto-17-phenyl trinor Prostaglandin F2α
CAS: 949564-89-0
MF: C23H30O5
MW: 386.48
EINECS:
MDL Number:MFCD03411997
Synonyms:15-keto-17-phenyl trinor Prostaglandin F2α;HHEYLKRDELKWGI-RKJYIPPQSA-N;(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-oxo-5-phenylpent-1-enyl]cyclopentyl]hept-5-enoic acid;15-keto-17-phenyl trinor Prostaglandin F2α;5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E)-3-oxo-5-phenyl-1-penten-1-yl]cyclopentyl]-, (5Z)-;9α,11α-dihydroxy-15-oxo-17-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-oicacid

Price4 Properties Safety Information Description

4 prices

Selected condition：

Brand

AK Scientific
Cayman Chemical

Package

1mg
5mg
10mg

ManufacturerAK Scientific
Product number0676DJ
Product description(Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E)-3-oxo-5-phenylpent-1-enyl]cyclopentyl]hept-5-enoicacid
Packaging10mg
Price$650
Updated2021-12-16
Buy

ManufacturerCayman Chemical
Product number16817
Product description15-keto-17-phenyl trinor Prostaglandin F2α ≥98%
Packaging1mg
Price$64
Updated2024-03-01
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ManufacturerCayman Chemical
Product number16817
Product description15-keto-17-phenyl trinor Prostaglandin F2α ≥98%
Packaging5mg
Price$280
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number16817
Product description15-keto-17-phenyl trinor Prostaglandin F2α ≥98%
Packaging10mg
Price$497
Updated2024-03-01
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
AK Scientific	0676DJ	(Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E)-3-oxo-5-phenylpent-1-enyl]cyclopentyl]hept-5-enoicacid	10mg	$650	2021-12-16	Buy
Cayman Chemical	16817	15-keto-17-phenyl trinor Prostaglandin F2α ≥98%	1mg	$64	2024-03-01	Buy
Cayman Chemical	16817	15-keto-17-phenyl trinor Prostaglandin F2α ≥98%	5mg	$280	2024-03-01	Buy
Cayman Chemical	16817	15-keto-17-phenyl trinor Prostaglandin F2α ≥98%	10mg	$497	2024-03-01	Buy

Properties

Boiling point :594.2±50.0 °C(Predicted)
Density :1.216±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 2.5 mg/ml
pka :4.76±0.10(Predicted)

Safety Information

Symbol(GHS):

Signal word:

Danger

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H225	Highly Flammable liquid and vapour	Flammable liquids	Category 2	Danger	P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H336	May cause drowsiness or dizziness	Specific target organ toxicity,single exposure; Narcotic effects	Category 3	Warning	P261, P271, P304+P340, P312,P403+P233, P405, P501
H360	May damage fertility or the unborn child	Reproductive toxicity	Category 1A, 1B	Danger

Precautionary statements:

P201	Obtain special instructions before use.
P202	Do not handle until all safety precautions have been read and understood.
P210	Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240	Ground/bond container and receiving equipment.
P241	Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242	Use only non-sparking tools.
P243	Take precautionary measures against static discharge.
P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P271	Use only outdoors or in a well-ventilated area.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353	IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313	IF exposed or concerned: Get medical advice/attention.
P312	Call a POISON CENTER or doctor/physician if you feel unwell.
P337+P313	IF eye irritation persists: Get medical advice/attention.
P370+P378	In case of fire: Use … for extinction.
P403+P233	Store in a well-ventilated place. Keep container tightly closed.
P403+P235	Store in a well-ventilated place. Keep cool.
P405	Store locked up.
P501	Dispose of contents/container to..…

Description

Bimatoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug. Oxidation of the C-15 hydroxyl group and amide hydrolysis of Bimatoprost produces 15-keto-17-phenyl trinor PGF2α. 15-keto-17-phenyl trinor PGF2α is a potential metabolite of bimatoprost when administered to animals. 15-keto PG analogs are potential minor impurities in commercial preparations of their corresponding bulk drug compounds. Although much less potent that the parent compound, 15-keto PGs still retain the ability to produce a small but measurable decrease (1 mm Hg) in the intraocular pressure of normal cynomolgus monkeys when administered at a dose of 1 μg/eye. 15-keto Latanoprost (15-keto-17-phenyl-13,14-dihydro trinor PGF2α isopropyl ester) is a miotic in the normal cat eye, causing an 8 mm reduction in pupillary diameter at 5 μg/eye. Again, this is not as potent as many other F-type PGs; for example, PGF2α will produce this degree of miosis at a dose of less than 1 μg/eye.

Suppliers and manufacturers

BOC Sciences Shanghai Hongye Biotechnology Co. Ltd Hangzhou Synstar pharmaceutical Technology CO.,Ltd Shanghai Yifei Biotechnology Co. , Ltd. TargetMol Chemicals Inc.

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