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ChemicalBook >> CAS DataBase List >> 4-Nitrobenzenesulfonyl chloride

4-Nitrobenzenesulfonyl chloride

4-Nitrobenzenesulfonyl chloride price.
  • $7.62 - $1590
  • Product name: 4-Nitrobenzenesulfonyl chloride
  • CAS: 98-74-8
  • MF: C6H4ClNO4S
  • MW: 221.62
  • EINECS:202-697-9
  • MDL Number:MFCD00007445
  • Synonyms:4-nitro-benzenesulfonylchlorid ;4-Nitrophenylsulfonyl chloride;p-Nitrobenzenesulfonic acid chloride;4-Nitrobenzenesulfonyl chloride,95%;4-Nitrobenzenesulfonyl chloride, 95% 25GR;The nitrobenzene sulfonyl chloride;5-Nitrobenzenesulfonyl chloride;4-Nitrobenzenesulfonyl chloride ,99%
Price69 Properties Safety Information Description
69 prices
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Brand
  • AccelPharmtech
  • Activate Scientific
  • AHH
  • AK Scientific
  • American Custom Chemicals Corporation
  • Apolloscientific
  • Atlantic Research Chemicals
  • Biosynth
  • Chem-Impex
  • Frontier Specialty Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Oakwood
  • Sigma-Aldrich
  • SynQuest Laboratories
  • TCI Chemical
  • Thermo Scientific Chemicals
  • TRC
  • Usbiological
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  • ManufacturerAccelPharmtech
  • Product numberRY1102
  • Product description4-nitrobenzene sulfonyl chloride 99%
  • Packaging20KG
  • Price$1590
  • Updated2026-05-21
  • Buy
  • ManufacturerAccelPharmtech
  • Product numberRY1102
  • Product description4-nitrobenzene sulfonyl chloride 99%
  • Packaging10KG
  • Price$930
  • Updated2026-05-21
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS33455
  • Product description4-Nitrobenzenesulfonylchloride 98%
  • Packaging25g
  • Price$36
  • Updated2026-06-04
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS33455
  • Product description4-Nitrobenzenesulfonylchloride 98%
  • Packaging5g
  • Price$25
  • Updated2026-06-04
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS33455
  • Product description4-Nitrobenzenesulfonylchloride 98%
  • Packaging100g
  • Price$103
  • Updated2026-06-04
  • Buy
  • ManufacturerAHH
  • Product numberMT-19715
  • Product description4-Nitrobenzenesulphonyl chloride 97%
  • Packaging1000g
  • Price$446
  • Updated2026-05-26
  • Buy
  • ManufacturerAK Scientific
  • Product numberK770
  • Product description4-Nitrobenzenesulfonyl chloride 98%(GC)
  • Packaging1kg
  • Price$448
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberK770
  • Product description4-Nitrobenzenesulfonyl chloride 98%(GC)
  • Packaging500g
  • Price$252
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberK770
  • Product description4-Nitrobenzenesulfonyl chloride 98%(GC)
  • Packaging100g
  • Price$70
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberK770
  • Product description4-Nitrobenzenesulfonyl chloride 98%(GC)
  • Packaging25g
  • Price$30
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberK770
  • Product description4-Nitrobenzenesulfonyl chloride 98%(GC)
  • Packaging5g
  • Price$18
  • Updated2026-06-04
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM1048417
  • Product description4-NITROBENZENESULFONYL CHLORIDE 95.00%
  • Packaging5MG
  • Price$495.13
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberOR28919
  • Product description4-Nitrobenzenesulphonylchloride
  • Packaging25g
  • Price$24
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberOR28919
  • Product description4-Nitrobenzenesulphonylchloride
  • Packaging5g
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR28919
  • Product description4-Nitrobenzenesulphonylchloride
  • Packaging100g
  • Price$58
  • Updated2021-12-16
  • Buy
  • ManufacturerAtlantic Research Chemicals
  • Product numberSC00121
  • Product description4-Nitrobenzene-1-sulphonyl chloride 95
  • Packaging25g
  • Price$15.24
  • Updated2026-05-23
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AccelPharmtech RY1102 4-nitrobenzene sulfonyl chloride 99% 20KG $1590 2026-05-21 Buy
AccelPharmtech RY1102 4-nitrobenzene sulfonyl chloride 99% 10KG $930 2026-05-21 Buy
Activate Scientific AS33455 4-Nitrobenzenesulfonylchloride 98% 25g $36 2026-06-04 Buy
Activate Scientific AS33455 4-Nitrobenzenesulfonylchloride 98% 5g $25 2026-06-04 Buy
Activate Scientific AS33455 4-Nitrobenzenesulfonylchloride 98% 100g $103 2026-06-04 Buy
AHH MT-19715 4-Nitrobenzenesulphonyl chloride 97% 1000g $446 2026-05-26 Buy
AK Scientific K770 4-Nitrobenzenesulfonyl chloride 98%(GC) 1kg $448 2026-06-04 Buy
AK Scientific K770 4-Nitrobenzenesulfonyl chloride 98%(GC) 500g $252 2026-06-04 Buy
AK Scientific K770 4-Nitrobenzenesulfonyl chloride 98%(GC) 100g $70 2026-06-04 Buy
AK Scientific K770 4-Nitrobenzenesulfonyl chloride 98%(GC) 25g $30 2026-06-04 Buy
AK Scientific K770 4-Nitrobenzenesulfonyl chloride 98%(GC) 5g $18 2026-06-04 Buy
American Custom Chemicals Corporation CHM1048417 4-NITROBENZENESULFONYL CHLORIDE 95.00% 5MG $495.13 2021-12-16 Buy
Apolloscientific OR28919 4-Nitrobenzenesulphonylchloride 25g $24 2021-12-16 Buy
Apolloscientific OR28919 4-Nitrobenzenesulphonylchloride 5g $15 2021-12-16 Buy
Apolloscientific OR28919 4-Nitrobenzenesulphonylchloride 100g $58 2021-12-16 Buy
Atlantic Research Chemicals SC00121 4-Nitrobenzene-1-sulphonyl chloride 95 25g $15.24 2026-05-23 Buy
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Properties

Melting point :75 °C
Boiling point :143-144 °C (1.5002 mmHg)
Density :1.602 (estimate)
vapor pressure :0.009Pa at 20℃
refractive index :1.6000 (estimate)
Flash point :143-144°C/1.5mm
storage temp. :Store below +30°C.
solubility :soluble in Toluene
form :Powder
color :yellow
PH :1 (H2O, 20℃)
Water Solubility :Insoluble
Sensitive :Moisture Sensitive
BRN :746543
Stability :Moisture Sensitive
InChI :1S/C6H4ClNO4S/c7-13(11,12)6-3-1-5(2-4-6)8(9)10/h1-4H
InChIKey :JXRGUPLJCCDGKG-UHFFFAOYSA-N
SMILES :[O-][N+](=O)c1ccc(cc1)S(Cl)(=O)=O
LogP :2.1 at 20℃
CAS DataBase Reference :98-74-8(CAS DataBase Reference)
NIST Chemistry Reference :4-Nitrobenzenesulphonyl chloride(98-74-8)
EPA Substance Registry System :Benzenesulfonyl chloride, 4-nitro- (98-74-8)

Safety Information

Symbol(GHS): Corrosion (GHS05)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H290 May be corrosive to metals Corrosive to Metals Category 1 Warning P234, P390, P404
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
Precautionary statements:
P234 Keep only in original container.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P363 Wash contaminated clothing before reuse.
P390 Absorb spillage to prevent material damage.
P405 Store locked up.
P406 Store in corrosive resistant/… container with a resistant inner liner.
P501 Dispose of contents/container to..…

Description

4-Nitrobenzenesulfonyl chloride is used as an intermediate for the synthesis of pharmaceuticals like foscmprenavir, darunavir and amprenavir. It is involved in the preparation of N-nosyl-alpha-amino acid for peptide synthesis. It is also used for stereoselective α-glucosylation of partially protected carbohydrates in association with silver tri-fluoromethanesulfonate, N,N-dimethylacetamide and triethylamine. It is widely used for the synthesis of hydroxylamines of sulfadiazine, sulfamethoxazole and [Cu(bipy)2Cl](nbs) (1) (bipy = 2,2'-bipyridine, nbs = 4-nitrobenzenesulfonate).

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Suppliers and manufacturers

Hangzhou Xinshuo New Material Technology Co., Ltd. Taizhou Pukai Pharmaceutical Technology Co. LTD Shanghai Taijilin Industrial Co., Ltd. Henan SIWEIYIN Medicines Co., Ltd. Energy Chemical Suzhou Highfine Biotech Co., Ltd Sichuan Kulinan Technology Co., Ltd Tianjin Branch Chong pharmaceutical intermediates Co., Ltd. TOKYO CHEMICAL INDUSTRY CO., LTD. TCI Europe