A-83-01
|
- $10 - $3420
- Product name: A-83-01
- CAS: 909910-43-6
- MF: C25H19N5S
- MW: 421.52
- EINECS:
- MDL Number:MFCD08705403
- Synonyms:A 83-01;A83-01;TGF inhibitor A-83-01;3-(6-methylpyridin-2-yl)-N-phenyl-4-(quinolin-4-yl)-1H-pyrazole-1-carbothioamide;TGF-β RI Kinase Inhibitor IV ;A 83-01, >=98%;3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide;A-83-01AB142092);ALK5 Inhibitor IV
56 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- ApexBio Technology
- Arctom
- AvaChem
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- TRC
Package
- 10mM(in 1mL DMSO)
- 2mg
- 1mg
- 10mM*1mLinDMSO
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 500mg
- 1G
- Manufactureraablocks
- Product numberAA006FP7
- Product description3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide ≥98%
- Packaging1mg
- Price$10
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA006FP7
- Product description3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide ≥98%
- Packaging5mg
- Price$37
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA006FP7
- Product description3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide 98%
- Packaging10mg
- Price$63
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA006FP7
- Product description3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide 98%
- Packaging25mg
- Price$122
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA006FP7
- Product description3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide 98%
- Packaging50mg
- Price$196
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA006FP7
- Product description3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide 98%
- Packaging100mg
- Price$290
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberR16065
- Product descriptionA 83-01 98%
- Packaging100MG
- Price$450
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberR16065
- Product descriptionA 83-01 98%
- Packaging1G
- Price$1650
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberR16065
- Product descriptionA 83-01 98%
- Packaging25MG
- Price$150
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberR16065
- Product descriptionA 83-01 98%
- Packaging5MG
- Price$65
- Updated2026-05-27
- Buy
- ManufacturerApexBio Technology
- Product numberA3133
- Product descriptionA 83-01
- Packaging10mg
- Price$75
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA3133
- Product descriptionA 83-01
- Packaging5mg
- Price$55
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA3133
- Product descriptionA 83-01
- Packaging25mg
- Price$160
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA3133
- Product descriptionA 83-01
- Packaging10mM(in 1mL DMSO)
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3133
- Product descriptionA 83-01
- Packaging10mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3133
- Product descriptionA 83-01
- Packaging50mg
- Price$223
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA006FP7 | 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide ≥98% | 1mg | $10 | 2026-05-28 | Buy |
| aablocks | AA006FP7 | 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide ≥98% | 5mg | $37 | 2026-05-28 | Buy |
| aablocks | AA006FP7 | 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide 98% | 10mg | $63 | 2026-05-28 | Buy |
| aablocks | AA006FP7 | 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide 98% | 25mg | $122 | 2026-05-28 | Buy |
| aablocks | AA006FP7 | 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide 98% | 50mg | $196 | 2026-05-28 | Buy |
| aablocks | AA006FP7 | 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide 98% | 100mg | $290 | 2026-05-28 | Buy |
| ACHEMBLOCK | R16065 | A 83-01 98% | 100MG | $450 | 2026-05-27 | Buy |
| ACHEMBLOCK | R16065 | A 83-01 98% | 1G | $1650 | 2026-05-27 | Buy |
| ACHEMBLOCK | R16065 | A 83-01 98% | 25MG | $150 | 2026-05-27 | Buy |
| ACHEMBLOCK | R16065 | A 83-01 98% | 5MG | $65 | 2026-05-27 | Buy |
| ApexBio Technology | A3133 | A 83-01 | 10mg | $75 | 2026-05-06 | Buy |
| ApexBio Technology | A3133 | A 83-01 | 5mg | $55 | 2026-05-06 | Buy |
| ApexBio Technology | A3133 | A 83-01 | 25mg | $160 | 2026-05-06 | Buy |
| ApexBio Technology | A3133 | A 83-01 | 10mM(in 1mL DMSO) | $120 | 2021-12-16 | Buy |
| ApexBio Technology | A3133 | A 83-01 | 10mg | $140 | 2021-12-16 | Buy |
| ApexBio Technology | A3133 | A 83-01 | 50mg | $223 | 2026-05-06 | Buy |
Properties
Melting point :111℃
Boiling point :590.0±60.0 °C(Predicted)
Density :1.27±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
pka :8.77±0.70(Predicted)
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
InChI :InChI=1S/C25H19N5S/c1-17-8-7-13-23(27-17)24-21(19-14-15-26-22-12-6-5-11-20(19)22)16-30(29-24)25(31)28-18-9-3-2-4-10-18/h2-16H,1H3,(H,28,31)
InChIKey :HIJMSZGHKQPPJS-UHFFFAOYSA-N
SMILES :N1(C(NC2=CC=CC=C2)=S)C=C(C2C3C(N=CC=2)=CC=CC=3)C(C2=NC(C)=CC=C2)=N1
Boiling point :590.0±60.0 °C(Predicted)
Density :1.27±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
pka :8.77±0.70(Predicted)
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
InChI :InChI=1S/C25H19N5S/c1-17-8-7-13-23(27-17)24-21(19-14-15-26-22-12-6-5-11-20(19)22)16-30(29-24)25(31)28-18-9-3-2-4-10-18/h2-16H,1H3,(H,28,31)
InChIKey :HIJMSZGHKQPPJS-UHFFFAOYSA-N
SMILES :N1(C(NC2=CC=CC=C2)=S)C=C(C2C3C(N=CC=2)=CC=CC=3)C(C2=NC(C)=CC=C2)=N1
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
A 83-01 (909910-43-6) is a potent and selective ALK4, 5 and 7 inhibitor.1,2IC50 = 45, 12 and 7.5 nM respectively. Prevents phosphorylation of Smad2/3 and growth inhibition induced by TGFβ.2Inhibits differentiation of rat induced pluripotent stem cells and increases clonal expansion efficiency.3Together with AMI-5, A83-01 enabled Oct4-induced reprogramming of mouse embryonic fibroblasts.4Cell permeable. Active in vivo.Related product price
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