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ChemicalBook >> CAS DataBase List >> ACS 67

ACS 67

ACS 67 price.
  • $78 - $1529
  • Product name: ACS 67
  • CAS: 1088434-86-9
  • MF: C32H38O5S3
  • MW: 598.84
  • EINECS:
  • MDL Number:MFCD18428027
  • Synonyms:ACS 67;ACS 67 Exclusive;JEEWZRQQYWVJCX-WEWVERJPSA-N;5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-, 4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl ester, (5Z)-
7 prices
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Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerAK Scientific
  • Product number1489AH
  • Product description7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((3r)-3-hydroxy-5-phenylpentyl)cyclopentyl)-4-(3-thioxo-3H-1,2-dithiol-5-yl)phenylester,5Z-heptenoicacid
  • Packaging1mg
  • Price$185
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1489AH
  • Product description7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((3r)-3-hydroxy-5-phenylpentyl)cyclopentyl)-4-(3-thioxo-3H-1,2-dithiol-5-yl)phenylester,5Z-heptenoicacid
  • Packaging10mg
  • Price$780
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3246
  • Product descriptionACS67
  • Packaging25mg
  • Price$1529
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13619
  • Product descriptionACS 67 ≥95%
  • Packaging1mg
  • Price$78
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13619
  • Product descriptionACS 67 ≥95%
  • Packaging5mg
  • Price$346
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13619
  • Product descriptionACS 67 ≥95%
  • Packaging10mg
  • Price$614
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13619
  • Product descriptionACS 67 ≥95%
  • Packaging25mg
  • Price$1340
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1489AH 7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((3r)-3-hydroxy-5-phenylpentyl)cyclopentyl)-4-(3-thioxo-3H-1,2-dithiol-5-yl)phenylester,5Z-heptenoicacid 1mg $185 2021-12-16 Buy
AK Scientific 1489AH 7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((3r)-3-hydroxy-5-phenylpentyl)cyclopentyl)-4-(3-thioxo-3H-1,2-dithiol-5-yl)phenylester,5Z-heptenoicacid 10mg $780 2021-12-16 Buy
ApexBio Technology C3246 ACS67 25mg $1529 2021-12-16 Buy
Cayman Chemical 13619 ACS 67 ≥95% 1mg $78 2024-03-01 Buy
Cayman Chemical 13619 ACS 67 ≥95% 5mg $346 2024-03-01 Buy
Cayman Chemical 13619 ACS 67 ≥95% 10mg $614 2024-03-01 Buy
Cayman Chemical 13619 ACS 67 ≥95% 25mg $1340 2024-03-01 Buy

Properties

storage temp. :Store at -20°C
solubility :≤2mg/ml in ethanol;20mg/ml in DMSO;30mg/ml in dimethyl formamide
form :crystalline solid

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Latanoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug for the treatment of glaucoma. Latanoprost is an isopropyl ester, a prodrug form which is converted to latanoprost (free acid) by endogenous esterase enzymes. The free acid form is 200 times more potent than latanoprost as an FP receptor ligand for the human recombinant FP receptor. ACS 67 is an analog of latanoprost (free acid) that contains a hydrogen sulfide releasing component conjugated to the latanoprost carboxyl group. In glaucomatous pigmented rabbits, ACS 67 reduced intra-ocular pressure (IOP) more rapidly and to a greater extent than latanoprost (15 versus 25.5 mm Hg at four hours) at a dose of 0.005% for each compound. ACS 67 also increased the levels of reduced glutathione and cGMP in the aqueous humor of glaucomatous pigmented rabbits better than latanoprost.