ADAMTS-5
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- $57 - $910
- Product name: ADAMTS-5
- CAS: 929634-33-3
- MF: C16H11ClF3N3OS3
- MW: 449.92
- EINECS:
- MDL Number:MFCD26936335
- Synonyms:(5Z)-5-[[5-[(4-chlorophenyl)methylsulfanyl]-1-methyl-3-(trifluoromethyl)pyrazol-4-yl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one;ADAMTS-5 inhibitor - Compound 12;4-Thiazolidinone, 5-[[5-[[(4-chlorophenyl)methyl]thio]-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]methylene]-2-thioxo-;ADAMTS-5 Inhibitor;ADAMTS5 Inhibitor,ADAMTS 5 Inhibitor;5-((5-((4-Chlorobenzyl)thio)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methylene)-2-thioxothiazolidin-4-one;ADAMTS-5 Inhibitor, 10 mM in DMSO;ADAMTS-5 Inhibitor ，E0649
8 prices
Selected condition：
Brand
- AK Scientific
- Axon Medchem
- Cayman Chemical
- TRC
Package
- 500μg
- 1mg
- 5mg
- 2x5mg
- 25mg
- 2x25mg
- ManufacturerAK Scientific
- Product number8811CW
- Product descriptionADAMTS-5inhibitor
- Packaging1mg
- Price$197
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2083
- Product descriptionADAMTS-5inhibitor-Compound12 100%
- Packaging2x5mg
- Price$220
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2083
- Product descriptionADAMTS-5inhibitor-Compound12 100%
- Packaging25mg
- Price$522.5
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2083
- Product descriptionADAMTS-5inhibitor-Compound12 100%
- Packaging2x25mg
- Price$792
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17188
- Product descriptionADAMTS-5 Inhibitor ≥95%
- Packaging500μg
- Price$57
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17188
- Product descriptionADAMTS-5 Inhibitor ≥95%
- Packaging1mg
- Price$89
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17188
- Product descriptionADAMTS-5 Inhibitor ≥95%
- Packaging5mg
- Price$330
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberA220230
- Product descriptionADAMTS-5Inhibitor
- Packaging25mg
- Price$910
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 8811CW | ADAMTS-5inhibitor | 1mg | $197 | 2021-12-16 | Buy |
| Axon Medchem | Axon2083 | ADAMTS-5inhibitor-Compound12 100% | 2x5mg | $220 | 2021-12-16 | Buy |
| Axon Medchem | Axon2083 | ADAMTS-5inhibitor-Compound12 100% | 25mg | $522.5 | 2021-12-16 | Buy |
| Axon Medchem | Axon2083 | ADAMTS-5inhibitor-Compound12 100% | 2x25mg | $792 | 2021-12-16 | Buy |
| Cayman Chemical | 17188 | ADAMTS-5 Inhibitor ≥95% | 500μg | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 17188 | ADAMTS-5 Inhibitor ≥95% | 1mg | $89 | 2024-03-01 | Buy |
| Cayman Chemical | 17188 | ADAMTS-5 Inhibitor ≥95% | 5mg | $330 | 2024-03-01 | Buy |
| TRC | A220230 | ADAMTS-5Inhibitor | 25mg | $910 | 2021-12-16 | Buy |
Properties
Density :1.59±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 20 mg/ml
form :A crystalline solid
pka :6.69±0.50(Predicted)
color :Light yellow to yellow
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 20 mg/ml
form :A crystalline solid
pka :6.69±0.50(Predicted)
color :Light yellow to yellow
Safety Information
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Description
A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5) is an aggrecanase in that it cleaves aggrecan, a major proteoglycan in cartilage. While it has key roles in cartilage destruction associated with osteoarthritis, ADAMTS-5 is also involved in other pathways, including neurological processes. ADAMTS-5 Inhibitor is an inhibitor of ADAMTS-5 (aggrecanase-2; IC50 = 1.1 μM) with 40-fold selectivity over ADAMTS-4 (aggrecanase-1).Suppliers and manufacturers
Aladdin Scientific
Shanghai EFE Biological Technology Co., Ltd.
Shanghai YuanYe Biotechnology Co., Ltd.
Tianjin Kailiqi Biotechnology Co., Ltd.
Shanghai Chaolan Chemical Technology Center
Shanghai Hongye Biotechnology Co. Ltd
BOC Sciences
Shanghai Dongyang Biotechnology Co., Ltd.
