ADAMTS-5
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- $52 - $2924
- Product name: ADAMTS-5
- CAS: 929634-33-3
- MF: C16H11ClF3N3OS3
- MW: 449.93
- EINECS:
- MDL Number:MFCD26936335
- Synonyms:(5Z)-5-[[5-[(4-chlorophenyl)methylsulfanyl]-1-methyl-3-(trifluoromethyl)pyrazol-4-yl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one;ADAMTS-5 inhibitor - Compound 12;4-Thiazolidinone, 5-[[5-[[(4-chlorophenyl)methyl]thio]-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]methylene]-2-thioxo-;ADAMTS-5 Inhibitor;ADAMTS5 Inhibitor,ADAMTS 5 Inhibitor;5-((5-((4-Chlorobenzyl)thio)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methylene)-2-thioxothiazolidin-4-one;ADAMTS-5 Inhibitor, 10 mM in DMSO;ADAMTS-5 Inhibitor ,E0649
36 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Arctom
- Axon Medchem
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- TRC
Package
- 500μg
- 2x5mg
- 2x25mg
- 100mg
- 200mg
- 250mg
- 1g
- 1mg
- 10mM*1mLinDMSO(Solution)
- 5mg
- 10mg
- 25mg
- 50mg
- 10mM*1mLinDMSO(Solid+Solvent)
- Manufactureraablocks
- Product numberAA01E5S9
- Product description5-((5-((4-Chlorobenzyl)thio)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methylene)-2-thioxothiazolidin-4-one
- Packaging1mg
- Price$52
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E5S9
- Product description5-((5-((4-Chlorobenzyl)thio)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methylene)-2-thioxothiazolidin-4-one
- Packaging5mg
- Price$92
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E5S9
- Product description5-((5-((4-Chlorobenzyl)thio)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methylene)-2-thioxothiazolidin-4-one
- Packaging10mg
- Price$124
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E5S9
- Product description5-((5-((4-Chlorobenzyl)thio)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methylene)-2-thioxothiazolidin-4-one
- Packaging25mg
- Price$192
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E5S9
- Product description5-((5-((4-Chlorobenzyl)thio)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methylene)-2-thioxothiazolidin-4-one
- Packaging50mg
- Price$276
- Updated2026-05-30
- Buy
- ManufacturerACHEMBLOCK
- Product numberY226527
- Product descriptionADAMTS-5 Inhibitor 97.00%
- Packaging10MG
- Price$155
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY226527
- Product descriptionADAMTS-5 Inhibitor 97.00%
- Packaging50MG
- Price$380
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number8811CW
- Product descriptionADAMTS-5inhibitor
- Packaging1mg
- Price$197
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-114996
- Product descriptionADAMTS-5Inhibitor 99.59%
- Packaging10mg
- Price$209
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-114996
- Product descriptionADAMTS-5Inhibitor 99.59%
- Packaging10mM*1mLinDMSO(Solution)
- Price$157
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-114996
- Product descriptionADAMTS-5Inhibitor 99.59%
- Packaging25mg
- Price$352
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-114996
- Product descriptionADAMTS-5Inhibitor 99.59%
- Packaging5mg
- Price$143
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-114996
- Product descriptionADAMTS-5Inhibitor 99.59%
- Packaging10mM*1mLinDMSO(Solid+Solvent)
- Price$150
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-114996
- Product descriptionADAMTS-5Inhibitor 99.59%
- Packaging200mg
- Price$1064
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-114996
- Product descriptionADAMTS-5Inhibitor 99.59%
- Packaging50mg
- Price$523
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-114996
- Product descriptionADAMTS-5Inhibitor 99.59%
- Packaging100mg
- Price$760
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01E5S9 | 5-((5-((4-Chlorobenzyl)thio)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methylene)-2-thioxothiazolidin-4-one | 1mg | $52 | 2026-05-30 | Buy |
| aablocks | AA01E5S9 | 5-((5-((4-Chlorobenzyl)thio)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methylene)-2-thioxothiazolidin-4-one | 5mg | $92 | 2026-05-30 | Buy |
| aablocks | AA01E5S9 | 5-((5-((4-Chlorobenzyl)thio)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methylene)-2-thioxothiazolidin-4-one | 10mg | $124 | 2026-05-30 | Buy |
| aablocks | AA01E5S9 | 5-((5-((4-Chlorobenzyl)thio)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methylene)-2-thioxothiazolidin-4-one | 25mg | $192 | 2026-05-30 | Buy |
| aablocks | AA01E5S9 | 5-((5-((4-Chlorobenzyl)thio)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methylene)-2-thioxothiazolidin-4-one | 50mg | $276 | 2026-05-30 | Buy |
| ACHEMBLOCK | Y226527 | ADAMTS-5 Inhibitor 97.00% | 10MG | $155 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y226527 | ADAMTS-5 Inhibitor 97.00% | 50MG | $380 | 2026-05-27 | Buy |
| AK Scientific | 8811CW | ADAMTS-5inhibitor | 1mg | $197 | 2021-12-16 | Buy |
| Arctom | HY-114996 | ADAMTS-5Inhibitor 99.59% | 10mg | $209 | 2026-05-26 | Buy |
| Arctom | HY-114996 | ADAMTS-5Inhibitor 99.59% | 10mM*1mLinDMSO(Solution) | $157 | 2026-05-26 | Buy |
| Arctom | HY-114996 | ADAMTS-5Inhibitor 99.59% | 25mg | $352 | 2026-05-26 | Buy |
| Arctom | HY-114996 | ADAMTS-5Inhibitor 99.59% | 5mg | $143 | 2026-05-26 | Buy |
| Arctom | HY-114996 | ADAMTS-5Inhibitor 99.59% | 10mM*1mLinDMSO(Solid+Solvent) | $150 | 2026-05-26 | Buy |
| Arctom | HY-114996 | ADAMTS-5Inhibitor 99.59% | 200mg | $1064 | 2026-05-26 | Buy |
| Arctom | HY-114996 | ADAMTS-5Inhibitor 99.59% | 50mg | $523 | 2026-05-26 | Buy |
| Arctom | HY-114996 | ADAMTS-5Inhibitor 99.59% | 100mg | $760 | 2026-05-26 | Buy |
Properties
Density :1.59±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 20 mg/ml
form :A crystalline solid
pka :6.69±0.50(Predicted)
color :Light yellow to yellow
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 20 mg/ml
form :A crystalline solid
pka :6.69±0.50(Predicted)
color :Light yellow to yellow
Safety Information
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Description
A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5) is an aggrecanase in that it cleaves aggrecan, a major proteoglycan in cartilage. While it has key roles in cartilage destruction associated with osteoarthritis, ADAMTS-5 is also involved in other pathways, including neurological processes. ADAMTS-5 Inhibitor is an inhibitor of ADAMTS-5 (aggrecanase-2; IC50 = 1.1 μM) with 40-fold selectivity over ADAMTS-4 (aggrecanase-1).Related product price
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Suppliers and manufacturers
BOC Sciences
Aladdin Scientific
Shanghai EFE Biological Technology Co., Ltd.
Shanghai YuanYe Biotechnology Co., Ltd.
Tianjin Kailiqi Biotechnology Co., Ltd.
Shanghai Chaolan Chemical Technology Center
Shanghai Hongye Biotechnology Co. Ltd
BOC Sciences




