AGM-1470
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- $61 - $14980
- Product name: AGM-1470
- CAS: 129298-91-5
- MF: C19H28ClNO6
- MW: 401.88
- EINECS:
- MDL Number:MFCD00870281
- Synonyms:NSC642492;O-(chloroacetylcarbamoyl)fumagillol;O-(CHLOROACETYLCARBAMOYL)FUMAGILLOLTNP-470 AGM-1470;[(3R,4S,5S,6R)-5-Methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-yl] N-(2-chloroacetyl)carbamate;AGM-1470;Carbamic acid, (chloroacetyl)-, (3R,4S,5S,6R)-5-methoxy-4-[ (2R,3R)-2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-1-oxaspiro[2.5]oct-6-yl ester;Tnp-470;N-(2-Chloroacetyl)carbamicacid(3R,4S,5S,6R)-5-Methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-1-oxaspiro[2.5]oct-6-ylester
44 prices
Selected condition：
Brand
- aablocks
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Cayman Chemical
- ChemScene
- JR MediChem
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 100mg
- 250mg
- 500mg
- 1g
- 2.5g
- 5g
- 10mM*1mLinDMSO(Solution)
- 1 mg
- 10g
- 10mM*1mLinDMSO(Solidorliquid+Solvent)
- Manufactureraablocks
- Product numberAA000YZD
- Product descriptionNsc642492 ≥98%
- Packaging5mg
- Price$101
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000YZD
- Product descriptionNsc642492 ≥98%
- Packaging10mg
- Price$191
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000YZD
- Product descriptionNsc642492 ≥98%
- Packaging25mg
- Price$451
- Updated2026-05-25
- Buy
- ManufacturerAK Scientific
- Product number7768BA
- Product descriptionO-(Chloroacetylcarbamoyl)fumagillol
- Packaging10mg
- Price$302
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0009209
- Product descriptionTNP-470 95.00%
- Packaging10MG
- Price$726.44
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3622
- Product descriptionTNP-470
- Packaging25mg
- Price$742
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC3622
- Product descriptionTNP-470
- Packaging25mg
- Price$469
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3622
- Product descriptionTNP-470
- Packaging10mg
- Price$346
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC3622
- Product descriptionTNP-470
- Packaging10mg
- Price$198
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3622
- Product descriptionTNP-470
- Packaging5mg
- Price$182
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC3622
- Product descriptionTNP-470
- Packaging5mg
- Price$104
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-101932
- Product descriptionTNP-470 99.87%
- Packaging1mg
- Price$84
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-101932
- Product descriptionTNP-470 99.87%
- Packaging10mM*1mLinDMSO(Solution)
- Price$183
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-101932
- Product descriptionTNP-470 99.87%
- Packaging5mg
- Price$167
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-101932
- Product descriptionTNP-470 99.87%
- Packaging10mM*1mLinDMSO(Solidorliquid+Solvent)
- Price$173
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-101932
- Product descriptionTNP-470 99.87%
- Packaging10mg
- Price$266
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA000YZD | Nsc642492 ≥98% | 5mg | $101 | 2026-05-25 | Buy |
| aablocks | AA000YZD | Nsc642492 ≥98% | 10mg | $191 | 2026-05-25 | Buy |
| aablocks | AA000YZD | Nsc642492 ≥98% | 25mg | $451 | 2026-05-25 | Buy |
| AK Scientific | 7768BA | O-(Chloroacetylcarbamoyl)fumagillol | 10mg | $302 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0009209 | TNP-470 95.00% | 10MG | $726.44 | 2021-12-16 | Buy |
| ApexBio Technology | C3622 | TNP-470 | 25mg | $742 | 2026-05-06 | Buy |
| ApexBio Technology | C3622 | TNP-470 | 25mg | $469 | 2021-12-16 | Buy |
| ApexBio Technology | C3622 | TNP-470 | 10mg | $346 | 2026-05-06 | Buy |
| ApexBio Technology | C3622 | TNP-470 | 10mg | $198 | 2021-12-16 | Buy |
| ApexBio Technology | C3622 | TNP-470 | 5mg | $182 | 2026-05-06 | Buy |
| ApexBio Technology | C3622 | TNP-470 | 5mg | $104 | 2021-12-16 | Buy |
| Arctom | HY-101932 | TNP-470 99.87% | 1mg | $84 | 2026-05-26 | Buy |
| Arctom | HY-101932 | TNP-470 99.87% | 10mM*1mLinDMSO(Solution) | $183 | 2026-05-26 | Buy |
| Arctom | HY-101932 | TNP-470 99.87% | 5mg | $167 | 2026-05-26 | Buy |
| Arctom | HY-101932 | TNP-470 99.87% | 10mM*1mLinDMSO(Solidorliquid+Solvent) | $173 | 2026-05-26 | Buy |
| Arctom | HY-101932 | TNP-470 99.87% | 10mg | $266 | 2026-05-26 | Buy |
Properties
Melting point :90-93°C
alpha :D24 -46.6° (c = 0.44 in CHCl3)
Density :1.26±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: >15mg/mL
pka :7.19±0.46(Predicted)
form :White to light yellow solid
color :White to Pale Yellow Waxy
Stability :Hygroscopic
InChIKey :MSHZHSPISPJWHW-PVDLLORBSA-N
SMILES :ClCC(=O)NC(=O)O[C@H]1[C@H]([C@@H]([C@]3(OC3)CC1)[C@]2(O[C@@H]2CC=C(C)C)C)OC
alpha :D24 -46.6° (c = 0.44 in CHCl3)
Density :1.26±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: >15mg/mL
pka :7.19±0.46(Predicted)
form :White to light yellow solid
color :White to Pale Yellow Waxy
Stability :Hygroscopic
InChIKey :MSHZHSPISPJWHW-PVDLLORBSA-N
SMILES :ClCC(=O)NC(=O)O[C@H]1[C@H]([C@@H]([C@]3(OC3)CC1)[C@]2(O[C@@H]2CC=C(C)C)C)OC
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
TNP-470 is a synthetic analog of fumagillin that inhibits angiogenesis. It irreversibly inactivates methionine aminopeptidase-2 (MetAP2; IC50 = 2 μM), blocking endothelial cell proliferation in vitro and angiogenesis in vivo. It is without effect on MetAP1. TNP-470 has therapeutic potential in cancer and microsporidiosis.More related product prices
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Methyl acetate
$7.62-1334.03 -
Sineptina
$20-1177.83 -
ETHYLENE OXIDE
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Suppliers and manufacturers
CONIER CHEM AND PHARMA LIMITED
HANGZHOU CLAP TECHNOLOGY CO.,LTD
HANGZHOU LEAP CHEM CO., LTD.
Aladdin Scientific
NANJING YINGWEN BIOTECHNOLOGY CO LTD
3B Pharmachem (Wuhan) International Co.,Ltd.
Guangzhou Isun Pharmaceutical Co., Ltd
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Sigma-Aldrich
