AMG 9810
|
- $34 - $2500
- Product name: AMG 9810
- CAS: 545395-94-6
- MF: C21H23NO3
- MW: 337.41
- EINECS:
- MDL Number:MFCD00955103
- Synonyms:3-[4-(TERT-BUTYL)PHENYL]-N-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)ACRYLAMIDE;AMG 9810;(2E)-N-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-3-[4-(1,1-DIMETHYLETHYL)PHENYL]-2-PROPENAMIDE;(2E)-N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-dimethylethyl)phenyl]-2-propanamide;2-PropenaMide, N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-diMethylethyl)phenyl]-, (2E)-;CS-2548;AMG 9810;AMG-9810;3-(4-tert-Butyl-phenyl)-N-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-acrylamide
50 prices
Selected condition：
Brand
- ACHEMBLOCK
- AHH
- AK Scientific
- Ambeed
- ApexBio Technology
- Axon Medchem
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Sigma-Aldrich
- Thermo Scientific Chemicals
- Tocris
- TRC
- Usbiological
Package
- 10mg
- 10mM*1mLinDMSO
- 5mg
- 25mg
- 50mg
- 10
- 50
- 100MG
- 250mg
- 1G
- 5G
- ManufacturerACHEMBLOCK
- Product numberP51284
- Product descriptionAMG 9810 95%
- Packaging100MG
- Price$125
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberP51284
- Product descriptionAMG 9810 95%
- Packaging1G
- Price$625
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberP51284
- Product descriptionAMG 9810 95%
- Packaging5G
- Price$2500
- Updated2026-05-27
- Buy
- ManufacturerAHH
- Product numberMT-09667
- Product description(2E)-N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-dimethylethyl)phenyl]-2-propenamide 98%
- Packaging1g
- Price$488
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberMT-09667
- Product description(2E)-N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-dimethylethyl) phenyl]-2-propenamide 97%
- Packaging1g
- Price$488
- Updated2026-05-25
- Buy
- ManufacturerAHH
- Product numberMT-09667
- Product description(2E)-N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-dimethylethyl) phenyl]-2-propenamide 97%
- Packaging1g
- Price$488
- Updated2026-05-26
- Buy
- ManufacturerAK Scientific
- Product number8773BA
- Product description(E)-3-(4-t-Butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide
- Packaging50mg
- Price$279
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA715034
- Product descriptionAMG 9810 98%
- Packaging250mg
- Price$249
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA715034
- Product descriptionAMG 9810 98%
- Packaging100mg
- Price$124
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA715034
- Product descriptionAMG 9810 98%
- Packaging5mg
- Price$34
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA715034
- Product descriptionAMG 9810 98%
- Packaging10mg
- Price$44
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA715034
- Product descriptionAMG 9810 98%
- Packaging50mg
- Price$78
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA715034
- Product descriptionAMG 9810 98%
- Packaging1g
- Price$620
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7018
- Product descriptionAMG 9810
- Packaging10mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7018
- Product descriptionAMG 9810
- Packaging10mg
- Price$70
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7018
- Product descriptionAMG 9810
- Packaging25mg
- Price$155
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ACHEMBLOCK | P51284 | AMG 9810 95% | 100MG | $125 | 2026-05-27 | Buy |
| ACHEMBLOCK | P51284 | AMG 9810 95% | 1G | $625 | 2026-05-27 | Buy |
| ACHEMBLOCK | P51284 | AMG 9810 95% | 5G | $2500 | 2026-05-27 | Buy |
| AHH | MT-09667 | (2E)-N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-dimethylethyl)phenyl]-2-propenamide 98% | 1g | $488 | 2021-12-16 | Buy |
| AHH | MT-09667 | (2E)-N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-dimethylethyl) phenyl]-2-propenamide 97% | 1g | $488 | 2026-05-25 | Buy |
| AHH | MT-09667 | (2E)-N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-dimethylethyl) phenyl]-2-propenamide 97% | 1g | $488 | 2026-05-26 | Buy |
| AK Scientific | 8773BA | (E)-3-(4-t-Butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide | 50mg | $279 | 2021-12-16 | Buy |
| Ambeed | A715034 | AMG 9810 98% | 250mg | $249 | 2021-12-16 | Buy |
| Ambeed | A715034 | AMG 9810 98% | 100mg | $124 | 2021-12-16 | Buy |
| Ambeed | A715034 | AMG 9810 98% | 5mg | $34 | 2021-12-16 | Buy |
| Ambeed | A715034 | AMG 9810 98% | 10mg | $44 | 2021-12-16 | Buy |
| Ambeed | A715034 | AMG 9810 98% | 50mg | $78 | 2021-12-16 | Buy |
| Ambeed | A715034 | AMG 9810 98% | 1g | $620 | 2021-12-16 | Buy |
| ApexBio Technology | B7018 | AMG 9810 | 10mg | $70 | 2021-12-16 | Buy |
| ApexBio Technology | B7018 | AMG 9810 | 10mg | $70 | 2026-05-06 | Buy |
| ApexBio Technology | B7018 | AMG 9810 | 25mg | $155 | 2021-12-16 | Buy |
Properties
Boiling point :512.5±50.0 °C(Predicted)
Density :1.175±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >5mg/mL
pka :12.22±0.20(Predicted)
form :powder
color :white to beige
InChI :1S/C21H23NO3/c1-21(2,3)16-7-4-15(5-8-16)6-11-20(23)22-17-9-10-18-19(14-17)25-13-12-24-18/h4-11,14H,12-13H2,1-3H3,(H,22,23)/b11-6+
InChIKey :GZTFUVZVLYUPRG-IZZDOVSWSA-N
SMILES :CC(C)(C)c1ccc(\C=C\C(=O)Nc2ccc3OCCOc3c2)cc1
Density :1.175±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >5mg/mL
pka :12.22±0.20(Predicted)
form :powder
color :white to beige
InChI :1S/C21H23NO3/c1-21(2,3)16-7-4-15(5-8-16)6-11-20(23)22-17-9-10-18-19(14-17)25-13-12-24-18/h4-11,14H,12-13H2,1-3H3,(H,22,23)/b11-6+
InChIKey :GZTFUVZVLYUPRG-IZZDOVSWSA-N
SMILES :CC(C)(C)c1ccc(\C=C\C(=O)Nc2ccc3OCCOc3c2)cc1
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||
| Precautionary statements: |
|
Description
AMG 9810 is a competitive antagonist of capsaicin activation of the vanilloid receptor 1 (TRPV1) (IC50s = 24.5 and 85.6 nM for human and rat, respectively). Additionally, it has been shown to compete with other modes of TRPV1 activation, including protons (IC50s = 92.7 and 294 nM for human and rat, respectively), heat (IC50s = 15.8 and 21 nM for human and rat, respectively), and the endogenous ligands: anandamide, N-arachidonyl dopamine (IC50s = 8.5 and 260 nM for human and rat, respectively), and oleoyldopamine. In a rat model of inflammatory pain induced by intraplantar injection of complete Freund’s adjuvant, 30-100 mg/kg AMG 9810 reverses thermal and mechanical hyperalgesia.Related product price
- BCTC
$41-1680 - 4-TERT-BUTYLSTYRENE
$9-912.29 - 545395-94-6
$34-2500
Suppliers and manufacturers
career henan chemical co
![(2E)-N-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-3-[4-(1,1-DIMETHYLETHYL)PHENYL]-2-PROPENAMIDE](https://img.chemicalbook.com/ProductImageEN/2020-1/small/666cff23-51c7-49f5-a336-a34eda87aa4b.png)
ATK CHEMICAL COMPANY LIMITED
InvivoChem
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Shanghai Acmec Biochemical Technology Co., Ltd.
Aladdin Scientific
SHANGHAI KEAN TECHNOLOGY CO., LTD.
Chongqing Chemdad Co., Ltd
3B Pharmachem (Wuhan) International Co.,Ltd.
$9.80 /1.79999995231628KG
(2E)-N-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-3-[4-(1,1-DIMETHYLETHYL)PHENYL]-2-PROPENAMIDE CAS:545395-94-6
(2E)-N-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-3-[4-(1,1-DIMETHYLETHYL)PHENYL]-2-PROPENAMIDE CAS:545395-94-6