AMG 9810
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- $10 - $2500
- Product name: AMG 9810
- CAS: 545395-94-6
- MF: C21H23NO3
- MW: 337.41
- EINECS:
- MDL Number:MFCD00955103
- Synonyms:3-[4-(TERT-BUTYL)PHENYL]-N-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)ACRYLAMIDE;AMG 9810;(2E)-N-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-3-[4-(1,1-DIMETHYLETHYL)PHENYL]-2-PROPENAMIDE;(2E)-N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-dimethylethyl)phenyl]-2-propanamide;2-PropenaMide, N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-diMethylethyl)phenyl]-, (2E)-;CS-2548;AMG 9810;AMG-9810;3-(4-tert-Butyl-phenyl)-N-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-acrylamide
52 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AHH
- AK Scientific
- Ambeed
- ApexBio Technology
- Axon Medchem
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Sigma-Aldrich
- Thermo Scientific Chemicals
- Tocris
- TRC
- Usbiological
Package
- 10
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 50
- 100mg
- 250mg
- 500mg
- 10mM*1mLinDMSO
- 1G
- 5G
- Manufactureraablocks
- Product numberAA01E4MN
- Product description(E)-3-(4-(tert-Butyl)phenyl)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acrylamide 98%
- Packaging1mg
- Price$10
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E4MN
- Product description(E)-3-(4-(tert-Butyl)phenyl)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acrylamide 98%
- Packaging5mg
- Price$18
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E4MN
- Product description(E)-3-(4-(tert-Butyl)phenyl)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acrylamide 98%
- Packaging10mg
- Price$23
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E4MN
- Product description(E)-3-(4-(tert-Butyl)phenyl)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acrylamide 98%
- Packaging50mg
- Price$60
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E4MN
- Product description(E)-3-(4-(tert-Butyl)phenyl)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acrylamide 98%
- Packaging100mg
- Price$92
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E4MN
- Product description(E)-3-(4-(tert-Butyl)phenyl)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acrylamide 98%
- Packaging250mg
- Price$156
- Updated2026-05-30
- Buy
- ManufacturerACHEMBLOCK
- Product numberP51284
- Product descriptionAMG 9810 95%
- Packaging100MG
- Price$125
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberP51284
- Product descriptionAMG 9810 95%
- Packaging1G
- Price$625
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberP51284
- Product descriptionAMG 9810 95%
- Packaging5G
- Price$2500
- Updated2026-05-27
- Buy
- ManufacturerAHH
- Product numberMT-09667
- Product description(2E)-N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-dimethylethyl) phenyl]-2-propenamide 97%
- Packaging1g
- Price$488
- Updated2026-05-26
- Buy
- ManufacturerAK Scientific
- Product number8773BA
- Product description(E)-3-(4-t-Butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide
- Packaging50mg
- Price$279
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA715034
- Product descriptionAMG 9810 98%
- Packaging100mg
- Price$124
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA715034
- Product descriptionAMG 9810 98%
- Packaging250mg
- Price$249
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA715034
- Product descriptionAMG 9810 98%
- Packaging50mg
- Price$78
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA715034
- Product descriptionAMG 9810 98%
- Packaging5mg
- Price$34
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA715034
- Product descriptionAMG 9810 98%
- Packaging10mg
- Price$44
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01E4MN | (E)-3-(4-(tert-Butyl)phenyl)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acrylamide 98% | 1mg | $10 | 2026-05-30 | Buy |
| aablocks | AA01E4MN | (E)-3-(4-(tert-Butyl)phenyl)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acrylamide 98% | 5mg | $18 | 2026-05-30 | Buy |
| aablocks | AA01E4MN | (E)-3-(4-(tert-Butyl)phenyl)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acrylamide 98% | 10mg | $23 | 2026-05-30 | Buy |
| aablocks | AA01E4MN | (E)-3-(4-(tert-Butyl)phenyl)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acrylamide 98% | 50mg | $60 | 2026-05-30 | Buy |
| aablocks | AA01E4MN | (E)-3-(4-(tert-Butyl)phenyl)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acrylamide 98% | 100mg | $92 | 2026-05-30 | Buy |
| aablocks | AA01E4MN | (E)-3-(4-(tert-Butyl)phenyl)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acrylamide 98% | 250mg | $156 | 2026-05-30 | Buy |
| ACHEMBLOCK | P51284 | AMG 9810 95% | 100MG | $125 | 2026-05-27 | Buy |
| ACHEMBLOCK | P51284 | AMG 9810 95% | 1G | $625 | 2026-05-27 | Buy |
| ACHEMBLOCK | P51284 | AMG 9810 95% | 5G | $2500 | 2026-05-27 | Buy |
| AHH | MT-09667 | (2E)-N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-dimethylethyl) phenyl]-2-propenamide 97% | 1g | $488 | 2026-05-26 | Buy |
| AK Scientific | 8773BA | (E)-3-(4-t-Butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide | 50mg | $279 | 2021-12-16 | Buy |
| Ambeed | A715034 | AMG 9810 98% | 100mg | $124 | 2021-12-16 | Buy |
| Ambeed | A715034 | AMG 9810 98% | 250mg | $249 | 2021-12-16 | Buy |
| Ambeed | A715034 | AMG 9810 98% | 50mg | $78 | 2021-12-16 | Buy |
| Ambeed | A715034 | AMG 9810 98% | 5mg | $34 | 2021-12-16 | Buy |
| Ambeed | A715034 | AMG 9810 98% | 10mg | $44 | 2021-12-16 | Buy |
Properties
Boiling point :512.5±50.0 °C(Predicted)
Density :1.175±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >5mg/mL
pka :12.22±0.20(Predicted)
form :powder
color :white to beige
InChI :1S/C21H23NO3/c1-21(2,3)16-7-4-15(5-8-16)6-11-20(23)22-17-9-10-18-19(14-17)25-13-12-24-18/h4-11,14H,12-13H2,1-3H3,(H,22,23)/b11-6+
InChIKey :GZTFUVZVLYUPRG-IZZDOVSWSA-N
SMILES :CC(C)(C)c1ccc(\C=C\C(=O)Nc2ccc3OCCOc3c2)cc1
Density :1.175±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >5mg/mL
pka :12.22±0.20(Predicted)
form :powder
color :white to beige
InChI :1S/C21H23NO3/c1-21(2,3)16-7-4-15(5-8-16)6-11-20(23)22-17-9-10-18-19(14-17)25-13-12-24-18/h4-11,14H,12-13H2,1-3H3,(H,22,23)/b11-6+
InChIKey :GZTFUVZVLYUPRG-IZZDOVSWSA-N
SMILES :CC(C)(C)c1ccc(\C=C\C(=O)Nc2ccc3OCCOc3c2)cc1
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
AMG 9810 is a competitive antagonist of capsaicin activation of the vanilloid receptor 1 (TRPV1) (IC50s = 24.5 and 85.6 nM for human and rat, respectively). Additionally, it has been shown to compete with other modes of TRPV1 activation, including protons (IC50s = 92.7 and 294 nM for human and rat, respectively), heat (IC50s = 15.8 and 21 nM for human and rat, respectively), and the endogenous ligands: anandamide, N-arachidonyl dopamine (IC50s = 8.5 and 260 nM for human and rat, respectively), and oleoyldopamine. In a rat model of inflammatory pain induced by intraplantar injection of complete Freund’s adjuvant, 30-100 mg/kg AMG 9810 reverses thermal and mechanical hyperalgesia.Related product price
-
BCTC
$15-4125 -
4-TERT-BUTYLSTYRENE
$9-912.29 -
545395-94-6
$10-2500
Suppliers and manufacturers
career henan chemical co
![(2E)-N-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-3-[4-(1,1-DIMETHYLETHYL)PHENYL]-2-PROPENAMIDE](https://img.chemicalbook.com/ProductImageEN/2020-1/small/666cff23-51c7-49f5-a336-a34eda87aa4b.png)
BOC Sciences
TargetMol Chemicals Inc.
Shanghai Acmec Biochemical Technology Co., Ltd.
Aladdin Scientific
Bide Pharmatech Ltd.
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Sigma-Aldrich
Shanghai Lollane Biological Technology Co.,Ltd.
Shanghai Beckham Medical Technology Co., Ltd
$9.80
(2E)-N-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-3-[4-(1,1-DIMETHYLETHYL)PHENYL]-2-PROPENAMIDE CAS:545395-94-6
(2E)-N-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-3-[4-(1,1-DIMETHYLETHYL)PHENYL]-2-PROPENAMIDE CAS:545395-94-6