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ChemicalBook >> CAS DataBase List >> APAMIN

APAMIN

APAMIN price.
  • $53 - $2010
  • Product name: APAMIN
  • CAS: 24345-16-2
  • MF: C79H131N31O24S4
  • MW: 2027.34
  • EINECS:246-182-7
  • MDL Number:MFCD00167944
  • Synonyms:APAMIN, BEE VENOM;APAMIN (HONEY BEE, APIS MELIFERA);apamine ;APAMIN FROM BEE VENOM;APAMIN FROM HONEY BEE VENOM;M.W. 2027.34 C79H131N31O24S4;L-Cys-L-Asn-L-Cys-L-Lys-L-Ala-L-Pro-L-Glu-L-Thr-L-Ala-L-Leu-L-Cys-L-Ala-L-Arg-L-Arg-L-Cys-L-Gln-L-Gln-L-His-NH2;CYS-ASN-CYS-LYS-ALA-PRO-GLU-THR-ALA-LEU-CYS-ALA-ARG- ARG-CYS-GLN-GLN-HIS-NH2(DISULFIDE BRIDGE:CYS1-CYS11, CYS3-CYS15)
18 prices
Selected condition:
Brand
  • Alfa Aesar
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Sigma-Aldrich
  • Tocris
  • Usbiological
Package
  • 1
  • 100ug
  • 250ug
  • 500μg
  • 500ug
  • 0.5mg
  • 1mg
  • 2mg
  • 5mg
  • ManufacturerAlfa Aesar
  • Product numberJ60961
  • Product descriptionApamin
  • Packaging0.5mg
  • Price$168
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6817
  • Product descriptionApamin
  • Packaging500ug
  • Price$173
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA73204
  • Product descriptionApamin
  • Packaging100ug
  • Price$53
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA73204
  • Product descriptionApamin
  • Packaging250ug
  • Price$105
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA73204
  • Product descriptionApamin
  • Packaging500ug
  • Price$185
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA73204
  • Product descriptionApamin
  • Packaging1mg
  • Price$321
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA73204
  • Product descriptionApamin
  • Packaging2mg
  • Price$546
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17082
  • Product descriptionApamin (trifluoroacetate salt) ≥95%
  • Packaging500μg
  • Price$160
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-7096
  • Product descriptionApamin
  • Packaging500ug
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-7096
  • Product descriptionApamin
  • Packaging1mg
  • Price$225
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number178270
  • Product descriptionApamin, Bee Venom - CAS 24345-16-2 - Calbiochem Polypeptide neurotoxin known to pass through the blood-brain barrier.
  • Packaging500μg
  • Price$182
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberA1289
  • Product descriptionApamin from bee venom, ≥95% (HPLC)
  • Packaging0.5mg
  • Price$298
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberA9459
  • Product descriptionApamin synthetic, ≥97% (HPLC)
  • Packaging0.5mg
  • Price$400
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberA1289
  • Product descriptionApamin from bee venom, ≥95% (HPLC)
  • Packaging1mg
  • Price$508
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberA1289
  • Product descriptionApamin from bee venom, ≥95% (HPLC)
  • Packaging5mg
  • Price$2010
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number1652
  • Product descriptionApamin
  • Packaging1
  • Price$318
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Alfa Aesar J60961 Apamin 0.5mg $168 2021-12-16 Buy
ApexBio Technology B6817 Apamin 500ug $173 2021-12-16 Buy
Biosynth Carbosynth FA73204 Apamin 100ug $53 2021-12-16 Buy
Biosynth Carbosynth FA73204 Apamin 250ug $105 2021-12-16 Buy
Biosynth Carbosynth FA73204 Apamin 500ug $185 2021-12-16 Buy
Biosynth Carbosynth FA73204 Apamin 1mg $321 2021-12-16 Buy
Biosynth Carbosynth FA73204 Apamin 2mg $546 2021-12-16 Buy
Cayman Chemical 17082 Apamin (trifluoroacetate salt) ≥95% 500μg $160 2024-03-01 Buy
ChemScene CS-7096 Apamin 500ug $125 2021-12-16 Buy
ChemScene CS-7096 Apamin 1mg $225 2021-12-16 Buy
Sigma-Aldrich 178270 Apamin, Bee Venom - CAS 24345-16-2 - Calbiochem Polypeptide neurotoxin known to pass through the blood-brain barrier. 500μg $182 2024-03-01 Buy
Sigma-Aldrich A1289 Apamin from bee venom, ≥95% (HPLC) 0.5mg $298 2024-03-01 Buy
Sigma-Aldrich A9459 Apamin synthetic, ≥97% (HPLC) 0.5mg $400 2024-03-01 Buy
Sigma-Aldrich A1289 Apamin from bee venom, ≥95% (HPLC) 1mg $508 2024-03-01 Buy
Sigma-Aldrich A1289 Apamin from bee venom, ≥95% (HPLC) 5mg $2010 2024-03-01 Buy
Tocris 1652 Apamin 1 $318 2021-12-16 Buy

Properties

Boiling point :847.17°C (rough estimate)
Density :1.63
refractive index :1.5530 (estimate)
storage temp. :-20°C
solubility :0.05 M acetic acid: 5 mg/mL, clear, colorless to faintly yellow
form :White solid with dark tan
Water Solubility :Soluble to 1 mg/ml in water
Merck :13,732

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P342+P311 IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

Description

Apamin is an 18 amino acid peptide toxin found in bee venom. It is a potent blocker of small conductance Ca2+-activated K+ (SK, KCa2) channels that is more effective at SK2 than SK1 and SK3 (IC50 values are 0.06-0.4, 1-12, and 1-13 nM, respectively). It is ineffective against SK4 at 1 μM. Apamin is used to elucidate the roles of these channels in cells and tissues expressing SK channels, including neurons, vascular endothelium, bladder smooth muscle, and certain types of cancer cells.

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