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ChemicalBook >> CAS DataBase List >> API-2

API-2

API-2 price.
  • $47 - $2100
  • Product name: API-2
  • CAS: 35943-35-2
  • MF: C13H16N6O4
  • MW: 320.3
  • EINECS:
  • MDL Number:MFCD00932413
  • Synonyms:API-2;6-AMINO-4-METHYL-8-(BETA-D-RIBOFURANOSYL)-4H,8H-PYRROLO[4,3,2-DE]PYRIMIDO[4,5-C]PYRIDAZINE;AKT/PKB SIGNALING INHIBITOR-2;AKT INHIBITOR V;1,5-DIHYDRO-5-METHYL-1-BETA-D-RIBOFURANOSYL-1,4,5,6,8-PENTAAZAACENAPHTHYLEN-3-AMINE;1,4,5,6,8-pentaazaacenaphthylen-3-amine,1,5-dihydro-5-methyl-1-beta-d-ribofura ;API-2 (Tricirbine);TRICIRIBINE
38 prices
Selected condition:
Brand
  • AHH
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 1mg
  • 2mg
  • 10
  • 10μg
  • 5MG
  • 0.01g
  • 10mg
  • 25MG
  • 50mg
  • 100mg
  • 1g
  • 400μL
  • ManufacturerAHH
  • Product numberMT-09744
  • Product description1,5-Dihydro-5-methyl-1-beta-D-ribofuranosyl-1,4,5,6,8pentaazaacenaphthylen-3-amine 98%
  • Packaging0.01g
  • Price$415
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001275
  • Product descriptionTRICIRIBINE HYDRATE 95.00%
  • Packaging5MG
  • Price$773.74
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001275
  • Product descriptionTRICIRIBINE HYDRATE 95.00%
  • Packaging25MG
  • Price$1343.73
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8541
  • Product descriptionTriciribine
  • Packaging5mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8541
  • Product descriptionTriciribine
  • Packaging10mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8541
  • Product descriptionTriciribine
  • Packaging50mg
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60328
  • Product descriptionTriciribine ≥98%
  • Packaging10mg
  • Price$288
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb530735
  • Product descriptionBIRC3
  • Packaging10μg
  • Price$991.1
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberNT08796
  • Product descriptionTriciribine
  • Packaging5mg
  • Price$72.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberNT08796
  • Product descriptionTriciribine
  • Packaging10mg
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberNT08796
  • Product descriptionTriciribine
  • Packaging25mg
  • Price$237.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010237
  • Product descriptionTriciribine ≥98%
  • Packaging1mg
  • Price$47
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010237
  • Product descriptionTriciribine ≥98%
  • Packaging5mg
  • Price$107
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010237
  • Product descriptionTriciribine ≥98%
  • Packaging10mg
  • Price$161
  • Updated2023-06-20
  • Buy
  • ManufacturerChemenu
  • Product numberCM141574
  • Product descriptionTriciribine 98%
  • Packaging100mg
  • Price$1052
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0968
  • Product descriptionTriciribine 99.81%
  • Packaging5mg
  • Price$96
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-09744 1,5-Dihydro-5-methyl-1-beta-D-ribofuranosyl-1,4,5,6,8pentaazaacenaphthylen-3-amine 98% 0.01g $415 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001275 TRICIRIBINE HYDRATE 95.00% 5MG $773.74 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001275 TRICIRIBINE HYDRATE 95.00% 25MG $1343.73 2021-12-16 Buy
ApexBio Technology A8541 Triciribine 5mg $85 2021-12-16 Buy
ApexBio Technology A8541 Triciribine 10mg $120 2021-12-16 Buy
ApexBio Technology A8541 Triciribine 50mg $400 2021-12-16 Buy
Arctom CFN60328 Triciribine ≥98% 10mg $288 2021-12-16 Buy
Biorbyt Ltd orb530735 BIRC3 10μg $991.1 2021-12-16 Buy
Biosynth Carbosynth NT08796 Triciribine 5mg $72.5 2021-12-16 Buy
Biosynth Carbosynth NT08796 Triciribine 10mg $125 2021-12-16 Buy
Biosynth Carbosynth NT08796 Triciribine 25mg $237.5 2021-12-16 Buy
Cayman Chemical 10010237 Triciribine ≥98% 1mg $47 2024-03-01 Buy
Cayman Chemical 10010237 Triciribine ≥98% 5mg $107 2024-03-01 Buy
Cayman Chemical 10010237 Triciribine ≥98% 10mg $161 2023-06-20 Buy
Chemenu CM141574 Triciribine 98% 100mg $1052 2021-12-16 Buy
ChemScene CS-0968 Triciribine 99.81% 5mg $96 2021-12-16 Buy

Properties

Melting point :207 °C (decomp)
Boiling point :459.21°C (rough estimate)
Density :1.2633 (rough estimate)
refractive index :1.7000 (estimate)
storage temp. :Store at RT
solubility :DMSO: >10mg/mL
form :powder
pka :12.35±0.70(Predicted)
color :tan
InChIKey :HOGVTUZUJGHKPL-HTVVRFAVSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Triciribine, also known as API-2, suppresses the phosphorylation level and kinase activity of Akt. Akt kinase inhibition has been shown to induce apoptosis and cell growth in cancer cell research. Triciribine can selectively inhibit Akt1, Akt2, and Akt3 without inhibiting known upstream activators,PDK1 and PI 3-Kinase, of Akt. Studies show that Triciribine in duces apoptosis and inhibits cell growth in cells that express atypical Akt1. Additionally, Triciribine has antineoplastic and antiviral activity at low micromolar and submicromolar concentrations, and has been demonstrated to inhibit incorporation of amino acids into proteins and purine nucleotide synthesis.

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