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ChemicalBook >> CAS DataBase List >> ARP100

ARP100

ARP100 price.
  • $32 - $5410
  • Product name: ARP100
  • CAS: 704888-90-4
  • MF: C17H20N2O5S
  • MW: 364.42
  • EINECS:
  • MDL Number:MFCD09971105
  • Synonyms:ARP100;N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)acetamide;2-[((1,1'-Biphenyl)-4-ylsulfonyl)-(1-methylethoxy)amino]-N-hydroxyacetamide;MMP-2 Inhibitor III;N-hydroxy-2-[(4-phenylphenyl)sulfonyl-propan-2-yloxyamino]acetamide;Acetamide, 2-[([1,1'-biphenyl]-4-ylsulfonyl)(1-methylethoxy)amino]-N-hydroxy-;N-Hydroxy-2-(N-isopropoxy-[1,1'-biphenyl]-4-ylsulfonamido)acetamide;metalloproteinase,Inhibitor,Matrix metalloproteinases,selective,matrigel,ARP 100,matrix,invasion,ARP100,anti-invasive,MMP,ARP-100,inhibit
39 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Sigma-Aldrich
  • Thermo Scientific Chemicals
  • Tocris
  • TRC
  • Usbiological
Package
  • 5
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250MG
  • 1G
  • Manufactureraablocks
  • Product numberAA006822
  • Product descriptionARP-100 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA006822
  • Product descriptionARP-100
  • Packaging5mg
  • Price$72
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA006822
  • Product descriptionARP-100
  • Packaging10mg
  • Price$99
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA006822
  • Product descriptionARP-100
  • Packaging25mg
  • Price$179
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA006822
  • Product descriptionARP-100
  • Packaging50mg
  • Price$318
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA006822
  • Product descriptionARP-100
  • Packaging100mg
  • Price$498
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberV153295
  • Product descriptionARP 100 98%
  • Packaging100MG
  • Price$1040
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberV153295
  • Product descriptionARP 100 98%
  • Packaging250MG
  • Price$2080
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberV153295
  • Product descriptionARP 100 98%
  • Packaging1G
  • Price$5410
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number0914AC
  • Product descriptionN-Hydroxy-2-(N-isopropoxy-[1,1'-biphenyl]-4-ylsulfonamido)acetamide
  • Packaging10mg
  • Price$305
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA443997
  • Product descriptionARP-100 96%
  • Packaging100mg
  • Price$310
  • Updated2026-06-05
  • Buy
  • ManufacturerAmbeed
  • Product numberA443997
  • Product descriptionN-Hydroxy-2-(N-isopropoxy-[1,1'-biphenyl]-4-ylsulfonamido)acetamide 95+%
  • Packaging1g
  • Price$3361
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA443997
  • Product descriptionARP-100 96%
  • Packaging250mg
  • Price$528
  • Updated2026-06-05
  • Buy
  • ManufacturerAmbeed
  • Product numberA443997
  • Product descriptionARP-100 96%
  • Packaging50mg
  • Price$183
  • Updated2026-06-05
  • Buy
  • ManufacturerAmbeed
  • Product numberA443997
  • Product descriptionARP-100 96%
  • Packaging25mg
  • Price$108
  • Updated2026-06-05
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0002644
  • Product description2-[((1,1'-BIPHENYL)-4-YL-SULFONYL)-(1-METHYLETHOXY)AMINO]-N-HYDROXYACETAMIDE 95.00%
  • Packaging1MG
  • Price$132.3
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA006822 ARP-100 ≥98% 1mg $32 2026-05-28 Buy
aablocks AA006822 ARP-100 5mg $72 2026-05-28 Buy
aablocks AA006822 ARP-100 10mg $99 2026-05-28 Buy
aablocks AA006822 ARP-100 25mg $179 2026-05-28 Buy
aablocks AA006822 ARP-100 50mg $318 2026-05-28 Buy
aablocks AA006822 ARP-100 100mg $498 2026-05-28 Buy
ACHEMBLOCK V153295 ARP 100 98% 100MG $1040 2026-05-27 Buy
ACHEMBLOCK V153295 ARP 100 98% 250MG $2080 2026-05-27 Buy
ACHEMBLOCK V153295 ARP 100 98% 1G $5410 2026-05-27 Buy
AK Scientific 0914AC N-Hydroxy-2-(N-isopropoxy-[1,1'-biphenyl]-4-ylsulfonamido)acetamide 10mg $305 2021-12-16 Buy
Ambeed A443997 ARP-100 96% 100mg $310 2026-06-05 Buy
Ambeed A443997 N-Hydroxy-2-(N-isopropoxy-[1,1'-biphenyl]-4-ylsulfonamido)acetamide 95+% 1g $3361 2021-12-16 Buy
Ambeed A443997 ARP-100 96% 250mg $528 2026-06-05 Buy
Ambeed A443997 ARP-100 96% 50mg $183 2026-06-05 Buy
Ambeed A443997 ARP-100 96% 25mg $108 2026-06-05 Buy
American Custom Chemicals Corporation INB0002644 2-[((1,1'-BIPHENYL)-4-YL-SULFONYL)-(1-METHYLETHOXY)AMINO]-N-HYDROXYACETAMIDE 95.00% 1MG $132.3 2021-12-16 Buy

Properties

storage temp. :Desiccate at +4°C
solubility :Soluble at 100mM in DMSO
form :Solid
color :Off-white to light yellow
InChI :1S/C17H20N2O5S/c1-13(2)24-19(12-17(20)18-21)25(22,23)16-10-8-15(9-11-16)14-6-4-3-5-7-14/h3-11,13,21H,12H2,1-2H3,(H,18,20)
InChIKey :PHGLPDURIUEELR-UHFFFAOYSA-N
SMILES :[S](=O)(=O)(N(OC(C)C)CC(=O)NO)c1ccc(cc1)c2ccccc2

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

Matrix metalloproteinases (MMPs) belong to a family of proteases that play a crucial role in tissue remodeling and repair by degrading extracellular matrix proteins to enable cell migration. During cancer progression both MMP-2 and MMP-9 play a role in metastatic tumor dispersion and angiogenesis. ARP 100 is a biphenylsulfonamide that acts as a selective inhibitor of MMP-2 demonstrating an IC50 value of 12 nM. Due to its specific zinc binding domain configuration, the inhibitory activity of ARP 100 is significantly less potent towards MMP-1, MMP-3, MMP-7, and MMP-9 (IC50 values are 50, 4.5, 50, and 2 μM, respectively). At 50 nM, ARP 100 suppresses the invasive behavior of HT1080 tumor cells grown on matrigel.

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