ARP100
|
- $32 - $5410
- Product name: ARP100
- CAS: 704888-90-4
- MF: C17H20N2O5S
- MW: 364.42
- EINECS:
- MDL Number:MFCD09971105
- Synonyms:ARP100;N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)acetamide;2-[((1,1'-Biphenyl)-4-ylsulfonyl)-(1-methylethoxy)amino]-N-hydroxyacetamide;MMP-2 Inhibitor III;N-hydroxy-2-[(4-phenylphenyl)sulfonyl-propan-2-yloxyamino]acetamide;Acetamide, 2-[([1,1'-biphenyl]-4-ylsulfonyl)(1-methylethoxy)amino]-N-hydroxy-;N-Hydroxy-2-(N-isopropoxy-[1,1'-biphenyl]-4-ylsulfonamido)acetamide;metalloproteinase,Inhibitor,Matrix metalloproteinases,selective,matrigel,ARP 100,matrix,invasion,ARP100,anti-invasive,MMP,ARP-100,inhibit
39 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Cayman Chemical
- ChemScene
- DC Chemicals
- Sigma-Aldrich
- Thermo Scientific Chemicals
- Tocris
- TRC
- Usbiological
Package
- 5
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250MG
- 1G
- Manufactureraablocks
- Product numberAA006822
- Product descriptionARP-100 ≥98%
- Packaging1mg
- Price$32
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA006822
- Product descriptionARP-100
- Packaging5mg
- Price$72
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA006822
- Product descriptionARP-100
- Packaging10mg
- Price$99
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA006822
- Product descriptionARP-100
- Packaging25mg
- Price$179
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA006822
- Product descriptionARP-100
- Packaging50mg
- Price$318
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA006822
- Product descriptionARP-100
- Packaging100mg
- Price$498
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberV153295
- Product descriptionARP 100 98%
- Packaging100MG
- Price$1040
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberV153295
- Product descriptionARP 100 98%
- Packaging250MG
- Price$2080
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberV153295
- Product descriptionARP 100 98%
- Packaging1G
- Price$5410
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number0914AC
- Product descriptionN-Hydroxy-2-(N-isopropoxy-[1,1'-biphenyl]-4-ylsulfonamido)acetamide
- Packaging10mg
- Price$305
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA443997
- Product descriptionARP-100 96%
- Packaging100mg
- Price$310
- Updated2026-06-05
- Buy
- ManufacturerAmbeed
- Product numberA443997
- Product descriptionN-Hydroxy-2-(N-isopropoxy-[1,1'-biphenyl]-4-ylsulfonamido)acetamide 95+%
- Packaging1g
- Price$3361
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA443997
- Product descriptionARP-100 96%
- Packaging250mg
- Price$528
- Updated2026-06-05
- Buy
- ManufacturerAmbeed
- Product numberA443997
- Product descriptionARP-100 96%
- Packaging50mg
- Price$183
- Updated2026-06-05
- Buy
- ManufacturerAmbeed
- Product numberA443997
- Product descriptionARP-100 96%
- Packaging25mg
- Price$108
- Updated2026-06-05
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0002644
- Product description2-[((1,1'-BIPHENYL)-4-YL-SULFONYL)-(1-METHYLETHOXY)AMINO]-N-HYDROXYACETAMIDE 95.00%
- Packaging1MG
- Price$132.3
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA006822 | ARP-100 ≥98% | 1mg | $32 | 2026-05-28 | Buy |
| aablocks | AA006822 | ARP-100 | 5mg | $72 | 2026-05-28 | Buy |
| aablocks | AA006822 | ARP-100 | 10mg | $99 | 2026-05-28 | Buy |
| aablocks | AA006822 | ARP-100 | 25mg | $179 | 2026-05-28 | Buy |
| aablocks | AA006822 | ARP-100 | 50mg | $318 | 2026-05-28 | Buy |
| aablocks | AA006822 | ARP-100 | 100mg | $498 | 2026-05-28 | Buy |
| ACHEMBLOCK | V153295 | ARP 100 98% | 100MG | $1040 | 2026-05-27 | Buy |
| ACHEMBLOCK | V153295 | ARP 100 98% | 250MG | $2080 | 2026-05-27 | Buy |
| ACHEMBLOCK | V153295 | ARP 100 98% | 1G | $5410 | 2026-05-27 | Buy |
| AK Scientific | 0914AC | N-Hydroxy-2-(N-isopropoxy-[1,1'-biphenyl]-4-ylsulfonamido)acetamide | 10mg | $305 | 2021-12-16 | Buy |
| Ambeed | A443997 | ARP-100 96% | 100mg | $310 | 2026-06-05 | Buy |
| Ambeed | A443997 | N-Hydroxy-2-(N-isopropoxy-[1,1'-biphenyl]-4-ylsulfonamido)acetamide 95+% | 1g | $3361 | 2021-12-16 | Buy |
| Ambeed | A443997 | ARP-100 96% | 250mg | $528 | 2026-06-05 | Buy |
| Ambeed | A443997 | ARP-100 96% | 50mg | $183 | 2026-06-05 | Buy |
| Ambeed | A443997 | ARP-100 96% | 25mg | $108 | 2026-06-05 | Buy |
| American Custom Chemicals Corporation | INB0002644 | 2-[((1,1'-BIPHENYL)-4-YL-SULFONYL)-(1-METHYLETHOXY)AMINO]-N-HYDROXYACETAMIDE 95.00% | 1MG | $132.3 | 2021-12-16 | Buy |
Properties
storage temp. :Desiccate at +4°C
solubility :Soluble at 100mM in DMSO
form :Solid
color :Off-white to light yellow
InChI :1S/C17H20N2O5S/c1-13(2)24-19(12-17(20)18-21)25(22,23)16-10-8-15(9-11-16)14-6-4-3-5-7-14/h3-11,13,21H,12H2,1-2H3,(H,18,20)
InChIKey :PHGLPDURIUEELR-UHFFFAOYSA-N
SMILES :[S](=O)(=O)(N(OC(C)C)CC(=O)NO)c1ccc(cc1)c2ccccc2
solubility :Soluble at 100mM in DMSO
form :Solid
color :Off-white to light yellow
InChI :1S/C17H20N2O5S/c1-13(2)24-19(12-17(20)18-21)25(22,23)16-10-8-15(9-11-16)14-6-4-3-5-7-14/h3-11,13,21H,12H2,1-2H3,(H,18,20)
InChIKey :PHGLPDURIUEELR-UHFFFAOYSA-N
SMILES :[S](=O)(=O)(N(OC(C)C)CC(=O)NO)c1ccc(cc1)c2ccccc2
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Matrix metalloproteinases (MMPs) belong to a family of proteases that play a crucial role in tissue remodeling and repair by degrading extracellular matrix proteins to enable cell migration. During cancer progression both MMP-2 and MMP-9 play a role in metastatic tumor dispersion and angiogenesis. ARP 100 is a biphenylsulfonamide that acts as a selective inhibitor of MMP-2 demonstrating an IC50 value of 12 nM. Due to its specific zinc binding domain configuration, the inhibitory activity of ARP 100 is significantly less potent towards MMP-1, MMP-3, MMP-7, and MMP-9 (IC50 values are 50, 4.5, 50, and 2 μM, respectively). At 50 nM, ARP 100 suppresses the invasive behavior of HT1080 tumor cells grown on matrigel.Related product price
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