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ChemicalBook >> CAS DataBase List >> ARRY-614

ARRY-614

ARRY-614 price.
  • $37 - $910
  • Product name: ARRY-614
  • CAS: 945614-12-0
  • MF: C31H33FN6O3
  • MW: 556.63
  • EINECS:
  • MDL Number:MFCD28502055
  • Synonyms:N-(3-tert-Butyl-1-p-tolyl-1H-pyrazol-5-yl)-N'-[5-fluoro-2-[1-(2-hydroxyethyl)-1H-indazol-5-yloxy]benzyl]urea;1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[[5-fluoro-2-[1-(2-hydroxyethyl)indazol-5-yl]oxyphenyl]methyl]urea;ARRY-614;pexmetinib,ARRY-614;1-(3-(tertbutyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(5-fluoro-2-((1-(2-hydroxyethyl)-1H-indazol-5-yl)oxy)benzyl)urea;Urea, N-[3-(1,1-dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N'-[[5-fluoro-2-[[1-(2-hydroxyethyl)-1H-indazol-5-yl]oxy]phenyl]methyl]-;Autophagy,p38 MAPK,ARRY 614,Pexmetinib,Inhibitor,ARRY614,inhibit;3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-1-[(5-fluoro-2-{[1-(2-hydroxyethyl)-1H-indazol-5-yl]oxy}phenyl)methyl]urea
Price14 Properties Safety Information Description
14 prices
Selected condition：
Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • ManufacturerAK Scientific
  • Product number1343DC
  • Product descriptionPexmetinib
  • Packaging5mg
  • Price$266
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6012
  • Product descriptionPexmetinib(ARRY-614)
  • Packaging5mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6012
  • Product descriptionPexmetinib(ARRY-614)
  • Packaging25mg
  • Price$380
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6012
  • Product descriptionPexmetinib(ARRY-614)
  • Packaging100mg
  • Price$800
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number26187
  • Product descriptionPexmetinib
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number26187
  • Product descriptionPexmetinib
  • Packaging5mg
  • Price$151
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number26187
  • Product descriptionPexmetinib
  • Packaging10mg
  • Price$283
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0012413
  • Product descriptionPexmetinib 99.90%
  • Packaging5mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0012413
  • Product descriptionPexmetinib 99.90%
  • Packaging10mg
  • Price$190
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0012413
  • Product descriptionPexmetinib 99.90%
  • Packaging25mg
  • Price$390
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0012413
  • Product descriptionPexmetinib 99.90%
  • Packaging50mg
  • Price$590
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0012413
  • Product descriptionPexmetinib 99.90%
  • Packaging100mg
  • Price$910
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberP293620
  • Product descriptionPexmetinib
  • Packaging5mg
  • Price$135
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberP293620
  • Product descriptionPexmetinib
  • Packaging100mg
  • Price$900
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1343DC Pexmetinib 5mg $266 2021-12-16 Buy
ApexBio Technology B6012 Pexmetinib(ARRY-614) 5mg $110 2021-12-16 Buy
ApexBio Technology B6012 Pexmetinib(ARRY-614) 25mg $380 2021-12-16 Buy
ApexBio Technology B6012 Pexmetinib(ARRY-614) 100mg $800 2021-12-16 Buy
Cayman Chemical 26187 Pexmetinib 1mg $37 2024-03-01 Buy
Cayman Chemical 26187 Pexmetinib 5mg $151 2024-03-01 Buy
Cayman Chemical 26187 Pexmetinib 10mg $283 2024-03-01 Buy
ChemScene CS-0012413 Pexmetinib 99.90% 5mg $110 2021-12-16 Buy
ChemScene CS-0012413 Pexmetinib 99.90% 10mg $190 2021-12-16 Buy
ChemScene CS-0012413 Pexmetinib 99.90% 25mg $390 2021-12-16 Buy
ChemScene CS-0012413 Pexmetinib 99.90% 50mg $590 2021-12-16 Buy
ChemScene CS-0012413 Pexmetinib 99.90% 100mg $910 2021-12-16 Buy
TRC P293620 Pexmetinib 5mg $135 2021-12-16 Buy
TRC P293620 Pexmetinib 100mg $900 2021-12-16 Buy

Properties

Boiling point :694.1±55.0 °C(Predicted)
Density :1.28±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in H2O; ≥107.6 mg/mL in DMSO; ≥113 mg/mL in EtOH
form :solid
pka :13.00±0.46(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Pexmetinib is a potent and orally bioavailable dual p38 MAPK/Tie-2 inhibitor preventing tumor growth.

Suppliers and manufacturers

career henan chemical co
Pexmetinib
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