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ChemicalBook >> CAS DataBase List >> AMG-47a

AMG-47a

AMG-47a price.
  • $51 - $6120
  • Product name: AMG-47a
  • CAS: 882663-88-9
  • MF: C29H28F3N5O2
  • MW: 535.56
  • EINECS:
  • MDL Number:MFCD09970318
  • Synonyms:AMG-47a;AMG-47;4-Methyl-3-[2-[[2-(4-morpholinyl)ethyl]amino]-6-quinazolinyl]-N-[3-(trifluoromethyl)phenyl]benzamide;4-Methyl-3-[2-[[2-(4-morpholinyl)ethyl]amino]-6-quinazolinyl]-N-[3-(trifluoromethyl)phenyl]benzamide AMG-47A;4-Methyl-3-(2-((2-morpholinoethyl)amino)quinazolin-6-yl)-N-(3-(trifluoromethyl)phenyl)benzamid;4-methyl-3-(2-((2-morpholinoethyl)amino)quinazolin-6-yl)-N-(3-(trifluoromethyl)phenyl)benzamide;AMG47A; GENETICIN;CS-1025
Price65 Properties Safety Information Description
65 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • Adipogen Life Sciences
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • TRC
Package
  • 10mM*1mLinDMSO(Solution)
  • 1mg
  • 10mM*1mLinDMSO
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 250MG
  • 1G
  • 1000mg
  • 5.00g
  • 5g
  • Manufactureraablocks
  • Product numberAA00GU58
  • Product descriptionAMG-47a 98
  • Packaging1mg
  • Price$51
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GU58
  • Product descriptionAMG-47a 98%
  • Packaging2mg
  • Price$64
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GU58
  • Product descriptionAMG-47a 98%
  • Packaging5mg
  • Price$76
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GU58
  • Product descriptionAMG-47a 98%
  • Packaging10mg
  • Price$111
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GU58
  • Product descriptionAMG-47a 98%
  • Packaging25mg
  • Price$221
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GU58
  • Product descriptionAMG-47a 98
  • Packaging50mg
  • Price$332
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GU58
  • Product descriptionAMG-47a 98
  • Packaging100mg
  • Price$479
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ70012
  • Product description4-methyl-3-(2-((2-morpholinoethyl)amino)quinazolin-6-yl)-N-(3-(trifluoromethyl)phenyl)benzamide 98%
  • Packaging100MG
  • Price$685
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ70012
  • Product description4-methyl-3-(2-((2-morpholinoethyl)amino)quinazolin-6-yl)-N-(3-(trifluoromethyl)phenyl)benzamide 98%
  • Packaging250MG
  • Price$1370
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ70012
  • Product description4-methyl-3-(2-((2-morpholinoethyl)amino)quinazolin-6-yl)-N-(3-(trifluoromethyl)phenyl)benzamide 98%
  • Packaging1G
  • Price$3560
  • Updated2026-05-27
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1007-M010
  • Product descriptionAMG-47a ≥95%
  • Packaging10mg
  • Price$659
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1007-M005
  • Product descriptionAMG-47a ≥95%
  • Packaging5mg
  • Price$416
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1007-M005
  • Product descriptionAMG-47a ≥95%
  • Packaging5mg
  • Price$416
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1007-M001
  • Product descriptionAMG-47a ≥95%
  • Packaging1mg
  • Price$211
  • Updated2026-05-06
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN1007
  • Product descriptionAMG-47a
  • Packaging5mg
  • Price$405
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN1007
  • Product descriptionAMG-47a
  • Packaging1mg
  • Price$215
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00GU58 AMG-47a 98 1mg $51 2026-05-28 Buy
aablocks AA00GU58 AMG-47a 98% 2mg $64 2026-05-28 Buy
aablocks AA00GU58 AMG-47a 98% 5mg $76 2026-05-28 Buy
aablocks AA00GU58 AMG-47a 98% 10mg $111 2026-05-28 Buy
aablocks AA00GU58 AMG-47a 98% 25mg $221 2026-05-28 Buy
aablocks AA00GU58 AMG-47a 98 50mg $332 2026-05-28 Buy
aablocks AA00GU58 AMG-47a 98 100mg $479 2026-05-28 Buy
ACHEMBLOCK Q70012 4-methyl-3-(2-((2-morpholinoethyl)amino)quinazolin-6-yl)-N-(3-(trifluoromethyl)phenyl)benzamide 98% 100MG $685 2026-05-27 Buy
ACHEMBLOCK Q70012 4-methyl-3-(2-((2-morpholinoethyl)amino)quinazolin-6-yl)-N-(3-(trifluoromethyl)phenyl)benzamide 98% 250MG $1370 2026-05-27 Buy
ACHEMBLOCK Q70012 4-methyl-3-(2-((2-morpholinoethyl)amino)quinazolin-6-yl)-N-(3-(trifluoromethyl)phenyl)benzamide 98% 1G $3560 2026-05-27 Buy
Adipogen Life Sciences SYN-1007-M010 AMG-47a ≥95% 10mg $659 2026-05-06 Buy
Adipogen Life Sciences SYN-1007-M005 AMG-47a ≥95% 5mg $416 2021-12-16 Buy
Adipogen Life Sciences SYN-1007-M005 AMG-47a ≥95% 5mg $416 2026-05-06 Buy
Adipogen Life Sciences SYN-1007-M001 AMG-47a ≥95% 1mg $211 2026-05-06 Buy
AK Scientific SYN1007 AMG-47a 5mg $405 2021-12-16 Buy
AK Scientific SYN1007 AMG-47a 1mg $215 2021-12-16 Buy
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Properties

Density :1.324
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :Powder
pka :13.23±0.70(Predicted)
color :Light yellow to yellow

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

AMG 47a is an orally bioavailable inhibitor of Lck, VEGF receptor 2 (VEGFR2/KDR), p38α, and JAK3 (IC50s = 0.2, 1, 3, and 72 nM, respectively). It is selective for these kinases over a panel of additional kinases including SYK, JNK1, and PKAβ (IC50s = 292 to >25,000 nM) but does inhibit Src (IC50 = 2 nM). It decreases IL-2, but not TNF-α, production induced by an anti-CD3 antibody in 50% whole blood and inhibits T cell proliferation in vitro in a mixed lymphocyte reaction assay (IC50 = 30 nM). AMG 47a (10, 30, and 100 mg/kg) has anti-inflammatory activity, decreasing production of IL-2 induced by an anti-CD3 antibody in mice. It also decreases levels of mutant oncogene KRASG12V in HeLa cells in a reporter assay when used at a concentration of 1 μM.

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Suppliers and manufacturers

career henan chemical co
4-methyl-3-[2-(2-morpholin-4-ylethylamino)quinazolin-6-yl]-N-[3-(trifluoromethyl)phenyl]benzamide
$1.00
4-methyl-3-[2-(2-morpholin-4-ylethylamino)quinazolin-6-yl]-N-[3-(trifluoromethyl)phenyl]benzamide CAS:882663-88-9
TargetMol Chemicals Inc.
AMG-47a
$38.00
AMG-47a CAS:882663-88-9
ATK CHEMICAL COMPANY LIMITED
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TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.