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ChemicalBook >> CAS DataBase List >> AZD7545

AZD7545

AZD7545 price.
  • $40 - $1194
  • Product name: AZD7545
  • CAS: 252017-04-2
  • MF: C19H18ClF3N2O5S
  • MW: 478.87
  • EINECS:
  • MDL Number:MFCD25976792
  • Synonyms:AZD7545;AZD7545/AZD-7545;4-[[3-Chloro-4-[[(2R)-3,3,3-trifluoro-2-hydroxy-2-methyl-1-oxopropyl]amino]phenyl]sulfonyl]-N,N-dimethylbenzamide;(R)-4-(3-chloro-4-(3,3,3-trifluoro-2-hydroxy-2-methylpropanamido)phenylsulfonyl)-N,N-dimethylbenzamide;Benzamide, 4-[[3-chloro-4-[[(2R)-3,3,3-trifluoro-2-hydroxy-2-methyl-1-oxopropyl]amino]phenyl]sulfonyl]-N,N-dimethyl-;AZD7545,(R)-4-(3-chloro-4-(3,3,3-trifluoro-2-hydroxy-2-methylpropanamido)phenylsulfonyl)-N,N-dimethylbenzamide;AZD 7547;AZD7547;(2,4-Dihydroxy-5-isopropylphenyl)5-[(4-methyl-1-piperazinyl)meth yl]-1,3-dihydro-2H-isoindol-2-ylmethanone, 99%
Price24 Properties Safety Information Description
24 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • ManufacturerAK Scientific
  • Product number2244AH
  • Product description4-[[3-Chloro-4-[[(2R)-3,3,3-trifluoro-2-hydroxy-2-methyl-1-oxopropyl]amino]phenyl]sulfonyl]-N,N-dimethylbenzamide
  • Packaging5mg
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA349552
  • Product descriptionAZD7545 98+%
  • Packaging5mg
  • Price$245
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA349552
  • Product descriptionAZD7545 98+%
  • Packaging10mg
  • Price$318
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA349552
  • Product descriptionAZD7545 98+%
  • Packaging50mg
  • Price$538
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1286
  • Product descriptionAZD7545
  • Packaging5mg
  • Price$170
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS528833
  • Product descriptionAZD7545 ≥98%
  • Packaging10mg
  • Price$315
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC103126
  • Product description4-[[3-Chloro-4-[[(2R)-3,3,3-trifluoro-2-hydroxy-2-methyl-1-oxopropyl]amino]phenyl]sulfonyl]-N,N-dimethylbenzamide
  • Packaging5mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC103126
  • Product description4-[[3-Chloro-4-[[(2R)-3,3,3-trifluoro-2-hydroxy-2-methyl-1-oxopropyl]amino]phenyl]sulfonyl]-N,N-dimethylbenzamide
  • Packaging10mg
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC103126
  • Product description4-[[3-Chloro-4-[[(2R)-3,3,3-trifluoro-2-hydroxy-2-methyl-1-oxopropyl]amino]phenyl]sulfonyl]-N,N-dimethylbenzamide
  • Packaging25mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC103126
  • Product description4-[[3-Chloro-4-[[(2R)-3,3,3-trifluoro-2-hydroxy-2-methyl-1-oxopropyl]amino]phenyl]sulfonyl]-N,N-dimethylbenzamide
  • Packaging50mg
  • Price$800
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC103126
  • Product description4-[[3-Chloro-4-[[(2R)-3,3,3-trifluoro-2-hydroxy-2-methyl-1-oxopropyl]amino]phenyl]sulfonyl]-N,N-dimethylbenzamide
  • Packaging100mg
  • Price$1000
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19282
  • Product descriptionAZD 7545 ≥98%
  • Packaging1mg
  • Price$40
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19282
  • Product descriptionAZD 7545 ≥98%
  • Packaging5mg
  • Price$146
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19282
  • Product descriptionAZD 7545 ≥98%
  • Packaging10mg
  • Price$274
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19282
  • Product descriptionAZD 7545 ≥98%
  • Packaging25mg
  • Price$632
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM251712
  • Product description(R)-4-((3-Chloro-4-(3,3,3-trifluoro-2-hydroxy-2-methylpropanamido)phenyl)sulfonyl)-N,N-dimethylbenzamide 95%+
  • Packaging100mg
  • Price$1194
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2244AH 4-[[3-Chloro-4-[[(2R)-3,3,3-trifluoro-2-hydroxy-2-methyl-1-oxopropyl]amino]phenyl]sulfonyl]-N,N-dimethylbenzamide 5mg $220 2021-12-16 Buy
Ambeed A349552 AZD7545 98+% 5mg $245 2021-12-16 Buy
Ambeed A349552 AZD7545 98+% 10mg $318 2021-12-16 Buy
Ambeed A349552 AZD7545 98+% 50mg $538 2021-12-16 Buy
ApexBio Technology B1286 AZD7545 5mg $170 2021-12-16 Buy
Arctom AS528833 AZD7545 ≥98% 10mg $315 2021-12-16 Buy
Biosynth Carbosynth FC103126 4-[[3-Chloro-4-[[(2R)-3,3,3-trifluoro-2-hydroxy-2-methyl-1-oxopropyl]amino]phenyl]sulfonyl]-N,N-dimethylbenzamide 5mg $300 2021-12-16 Buy
Biosynth Carbosynth FC103126 4-[[3-Chloro-4-[[(2R)-3,3,3-trifluoro-2-hydroxy-2-methyl-1-oxopropyl]amino]phenyl]sulfonyl]-N,N-dimethylbenzamide 10mg $400 2021-12-16 Buy
Biosynth Carbosynth FC103126 4-[[3-Chloro-4-[[(2R)-3,3,3-trifluoro-2-hydroxy-2-methyl-1-oxopropyl]amino]phenyl]sulfonyl]-N,N-dimethylbenzamide 25mg $600 2021-12-16 Buy
Biosynth Carbosynth FC103126 4-[[3-Chloro-4-[[(2R)-3,3,3-trifluoro-2-hydroxy-2-methyl-1-oxopropyl]amino]phenyl]sulfonyl]-N,N-dimethylbenzamide 50mg $800 2021-12-16 Buy
Biosynth Carbosynth FC103126 4-[[3-Chloro-4-[[(2R)-3,3,3-trifluoro-2-hydroxy-2-methyl-1-oxopropyl]amino]phenyl]sulfonyl]-N,N-dimethylbenzamide 100mg $1000 2021-12-16 Buy
Cayman Chemical 19282 AZD 7545 ≥98% 1mg $40 2024-03-01 Buy
Cayman Chemical 19282 AZD 7545 ≥98% 5mg $146 2024-03-01 Buy
Cayman Chemical 19282 AZD 7545 ≥98% 10mg $274 2024-03-01 Buy
Cayman Chemical 19282 AZD 7545 ≥98% 25mg $632 2024-03-01 Buy
Chemenu CM251712 (R)-4-((3-Chloro-4-(3,3,3-trifluoro-2-hydroxy-2-methylpropanamido)phenyl)sulfonyl)-N,N-dimethylbenzamide 95%+ 100mg $1194 2021-12-16 Buy
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Properties

Boiling point :683.1±55.0 °C(Predicted)
Density :1.473±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :≥21.85 mg/mL in DMSO; insoluble in H2O; ≥15.63 mg/mL in EtOH with ultrasonic
form :solid
pka :10.39±0.29(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

AZD 7545 is an inhibitor of pyruvate dehydrogenase (PDH) kinases (PDKs), resulting in an increase in PDH activity with an EC50 value of 5.2 nM for PDK2. It less potently inhibits PDK1 and PDK3 (IC50s = 87 and 600 nM, respectively). AZD 7545 stimulates pyruvate oxidation in rat hepatocytes (EC50 = 105 nM) and significantly elevates muscle PDH activity in obese Zucker rats. It elevates postprandial glucose levels and improves the 24 hour glucose profile in obese, insulin-resistant rats, compared with lean counterparts.

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Suppliers and manufacturers

career henan chemical co
AZD7545
$1.00 /1KG
AZD7545 CAS: 252017-04-2
ATK CHEMICAL COMPANY LIMITED
Chongqing Chemdad Co., Ltd
TargetMol Chemicals Inc.
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
ShenZhen Trendseen Biological Technology Co.,Ltd.
Wuhan Topule Biopharmaceutical Co., Ltd
LEAPCHEM CO., LTD.
Shanghai Acmec Biochemical Technology Co., Ltd.