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ChemicalBook >> CAS DataBase List >> Aminoquinol

Aminoquinol

Aminoquinol price.
  • $30 - $560
  • Product name: Aminoquinol
  • CAS: 10023-54-8
  • MF: C26H31Cl2N3
  • MW: 456.45
  • EINECS:
  • MDL Number:MFCD01709344
  • Synonyms:Aminoquinol;7-Chloro-2-(o-chlorostyryl)-4-[[4-(diethylamino)-1-methylbutyl]amino]quinoline;N-*4*-{7-Chloro-2-[2-(2-chloro-phenyl)-vinyl]-quin olin-4-yl}-N*1*,N*1*-diethyl-pentane-1,4-diami;N-*4*-{7-Chloro-2-[2-(2-chloro-phenyl)-vinyl]-quinolin-4-yl}-N*1*,N*1*-diethyl-pentane-1,4-dia;N4-{7-chloro-2-[2-(2-chlorophenyl)vinyl]-4-quinolinyl}-N1,N1-diethyl-1,4-pentanediamine tris(phosphate);1,4-Pentanediamine, N4-[7-chloro-2-[2-(2-chlorophenyl)ethenyl]-4-quinolinyl]-N1,N1-diethyl-;Aminoquinol DISCONTINUED. Please see C609759.
Price4 Properties Safety Information Description
4 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Aronis compounds
  • Matrix Scientific
Package
  • 5MG
  • 20mg
  • 1g
  • ManufacturerAK Scientific
  • Product number7133AC
  • Product descriptionN4-{7-Chloro-2-[2-(2-chloro-phenyl)-vinyl]-quinolin-4-yl}-N1,N1-diethyl-pentane-1,4-diamine
  • Packaging1g
  • Price$560
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0025379
  • Product descriptionAMINOQUINOL 95.00%
  • Packaging5MG
  • Price$501.2
  • Updated2021-12-16
  • Buy
  • ManufacturerAronis compounds
  • Product numbere00599
  • Product descriptionN4-{7-chloro-2-[2-(2-chlorophenyl)vinyl]-4-quinolinyl}-N1,N1-diethyl-1,4-pentanediaminetris(phosphate)
  • Packaging20mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number009881
  • Product descriptionN-*4*-{7-Chloro-2-[2-(2-chloro-phenyl)-vinyl]-quinolin-4-yl}-N*1*,N*1*-diethyl-pentane-1,4-diamine triphosphate
  • Packaging1g
  • Price$378
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 7133AC N4-{7-Chloro-2-[2-(2-chloro-phenyl)-vinyl]-quinolin-4-yl}-N1,N1-diethyl-pentane-1,4-diamine 1g $560 2021-12-16 Buy
American Custom Chemicals Corporation API0025379 AMINOQUINOL 95.00% 5MG $501.2 2021-12-16 Buy
Aronis compounds e00599 N4-{7-chloro-2-[2-(2-chlorophenyl)vinyl]-4-quinolinyl}-N1,N1-diethyl-1,4-pentanediaminetris(phosphate) 20mg $30 2021-12-16 Buy
Matrix Scientific 009881 N-*4*-{7-Chloro-2-[2-(2-chloro-phenyl)-vinyl]-quinolin-4-yl}-N*1*,N*1*-diethyl-pentane-1,4-diamine triphosphate 1g $378 2021-12-16 Buy

Properties

Melting point :223-225°
Boiling point :597.1±50.0 °C(Predicted)
Density :1.191±0.06 g/cm3(Predicted)
storage temp. :RT
solubility :Soluble in DMSO (up to 25 mg/ml with warming).
form :solid
pka :10.47±0.25(Predicted)
color :Light brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

XIB4035 (10023-54-8) is a novel small molecule thought to be an agonist at the glial cell line-derived neurotrophic factor (GDNF) family receptor GFRα-1. It inhibits radiolabeled GDNF binding in Neuro-2A cells in a concentration dependent manner IC50?= 10.4 μM. Like GDNF, XIB4035 induced Ret autophosphorylation and promoted neurite outgrowth in Neuro-2A cells.1?Recent studies indicate that it enhances GFRα family receptor signaling in conjunction with ligand stimulation. Effective treatment for small-fiber neuropathy in mouse models of the disease.2,3? GDNF agonists may be a new class of Parkinson’s disease therapeutics.4

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Suppliers and manufacturers

J & K SCIENTIFIC LTD. Clearsynth Labs Limited ShangHai Biochempartner Co.,Ltd Wuhan Topule Changzhou Furuisi Biotechnology Co., Ltd Hubei Kele Fine Chemical Co., Ltd Wuhan Yingnuo Pharmaceutical Technology Co., Ltd. Shanghai jerryxing Biomedical Technology Co., Ltd Olix (Shanghai) Pharmaceutical Technology Co., Ltd Aronis