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ChemicalBook >> CAS DataBase List >> Ampicillin

Ampicillin

Ampicillin price.
  • $13 - $499
  • Product name: Ampicillin
  • CAS: 69-53-4
  • MF: C16H19N3O4S
  • MW: 349.4
  • EINECS:200-709-7
  • MDL Number:MFCD00072036
  • Synonyms:D(-)-ALPHA-AMINOBENZYLPENICILLIN;D(-)-ALPHA-AMINOBENZYLPENICILLIN TRIHYDRATE;D(-)-aplha-aminobenzylpenicillin;Marisilan;Penstabil;Rosampline;6-[D-ALPHA-AMINOPHENYLACETAMIDO]PENICILLANIC ACID TRIHYDRATE;ALPHA-AMINOBENZYLPENICILLIN, TRIHYDRATE
24 prices
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  • AHH
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • Arctom
  • Biorbyt Ltd
  • ChemScene
  • Sigma-Aldrich
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  • Usbiological
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  • a1000000
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  • ManufacturerAHH
  • Product numberAPI-1029
  • Product descriptionAmpicillin 98%
  • Packaging250g
  • Price$310
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberK161
  • Product descriptionAmpicillin
  • Packaging5g
  • Price$35
  • Updated2021-12-16
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  • ManufacturerAlfa Aesar
  • Product numberJ60977
  • Product descriptionAmpicillin
  • Packaging5g
  • Price$130
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ60977
  • Product descriptionAmpicillin
  • Packaging25g
  • Price$365
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA251599
  • Product description(2S,5R,6R)-6-[(R)-2-Amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid 97%+(Lossondrying≤15%)
  • Packaging5g
  • Price$13
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA251599
  • Product description(2S,5R,6R)-6-[(R)-2-Amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid 97%+(Lossondrying≤15%)
  • Packaging25g
  • Price$43
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCCH0007084
  • Product description(2S,5R,6R)-6-[[(2R)-2-AMINO-2-PHENYLACETYL]AMINO]-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID 95.00%
  • Packaging5MG
  • Price$496.85
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS494683
  • Product description(2S,5R,6R)-6-[(R)-2-Amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid 98%
  • Packaging5g
  • Price$32
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS494683
  • Product description(2S,5R,6R)-6-[(R)-2-Amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid 98%
  • Packaging25g
  • Price$126
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS494683
  • Product description(2S,5R,6R)-6-[(R)-2-Amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid 98%
  • Packaging100g
  • Price$451
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb595980
  • Product descriptionDDO
  • Packaging10μg
  • Price$290.7
  • Updated2021-12-16
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  • ManufacturerChemScene
  • Product numberCS-2741
  • Product descriptionAmpicillin 99.47%
  • Packaging500mg
  • Price$70
  • Updated2021-12-16
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  • ManufacturerChemScene
  • Product numberCS-2741
  • Product descriptionAmpicillin 99.47%
  • Packaging1g
  • Price$114
  • Updated2021-12-16
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  • ManufacturerSigma-Aldrich
  • Product number59349
  • Product descriptionAmpicillin analytical standard
  • Packaging100mg
  • Price$54.7
  • Updated2024-03-01
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  • ManufacturerSigma-Aldrich
  • Product numberA9393
  • Product descriptionAmpicillin anhydrous, 96.0-100.5% (anhydrous basis)
  • Packaging5g
  • Price$79.2
  • Updated2024-03-01
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  • ManufacturerSigma-Aldrich
  • Product numberA5354
  • Product descriptionAmpicillin Ready Made Solution, 100?mg/mL, 0.2 μm filtered
  • Packaging10ml
  • Price$112
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH API-1029 Ampicillin 98% 250g $310 2021-12-16 Buy
AK Scientific K161 Ampicillin 5g $35 2021-12-16 Buy
Alfa Aesar J60977 Ampicillin 5g $130 2024-03-01 Buy
Alfa Aesar J60977 Ampicillin 25g $365 2024-03-01 Buy
Ambeed A251599 (2S,5R,6R)-6-[(R)-2-Amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid 97%+(Lossondrying≤15%) 5g $13 2021-12-16 Buy
Ambeed A251599 (2S,5R,6R)-6-[(R)-2-Amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid 97%+(Lossondrying≤15%) 25g $43 2021-12-16 Buy
American Custom Chemicals Corporation CCH0007084 (2S,5R,6R)-6-[[(2R)-2-AMINO-2-PHENYLACETYL]AMINO]-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID 95.00% 5MG $496.85 2021-12-16 Buy
Arctom AS494683 (2S,5R,6R)-6-[(R)-2-Amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid 98% 5g $32 2021-12-16 Buy
Arctom AS494683 (2S,5R,6R)-6-[(R)-2-Amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid 98% 25g $126 2021-12-16 Buy
Arctom AS494683 (2S,5R,6R)-6-[(R)-2-Amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid 98% 100g $451 2021-12-16 Buy
Biorbyt Ltd orb595980 DDO 10μg $290.7 2021-12-16 Buy
ChemScene CS-2741 Ampicillin 99.47% 500mg $70 2021-12-16 Buy
ChemScene CS-2741 Ampicillin 99.47% 1g $114 2021-12-16 Buy
Sigma-Aldrich 59349 Ampicillin analytical standard 100mg $54.7 2024-03-01 Buy
Sigma-Aldrich A9393 Ampicillin anhydrous, 96.0-100.5% (anhydrous basis) 5g $79.2 2024-03-01 Buy
Sigma-Aldrich A5354 Ampicillin Ready Made Solution, 100?mg/mL, 0.2 μm filtered 10ml $112 2024-03-01 Buy

Properties

Melting point :198-200 °C (dec.)(lit.)
alpha :D23 +287.9° (c = 1 in water)
Boiling point :201.8°C (rough estimate)
Density :1.2794 (rough estimate)
refractive index :1.6320 (estimate)
storage temp. :2-8°C
solubility :NH4OH 1 M: 50 mg/mL, clear, colorless
form :solid
color :White to Pale Yellow
pka :2.5 (COOH)(at 25℃)
optical activity :+287.923 (c 1.0, H2O)
Water Solubility :13.9g/L(25 ºC)
JECFA Number :85
Merck :13,591
BRN :1090925
Stability :Stable, but may be moisture sensitive. Incopmpatible with strong oxidizing agents.
InChIKey :AVKUERGKIZMTKX-NJBDSQKTSA-N
CAS DataBase Reference :69-53-4(CAS DataBase Reference)
IARC :3 (Vol. 50) 1990
EPA Substance Registry System :Ampicillin (69-53-4)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 Wear respiratory protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.

Description

Ampicillin is an antibacterial antibiotic from the α-aminobenzyl penicillin group, which differs from penicillin by the presence of an amino group that facilitates penetration through the outer membrane of some gram-negative bacteria.
Ampicillin is Semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic. Ampicillin acts by interfering directly with the biosynthesis of peptidoglycan, which constitutes the major component of the bacterial cell wall, leading to structural instability and death of bacteria.
Ampicillin is a β-lactam antibiotic within the penicillin family. As a member of this family, Ampicillin is susceptible to β-lactamase, which hydrolyzes the β-lactam ring. This broad spectrum antibiotic is effective against gram-positive, gram-negative bacteria and anaerobic bacteria. Ampicillin is widely used in cell culture as a selective agent. As an antibiotic, Ampicillin binds to penicillin binding proteins (PBPs) on a susceptible organism and Inhibits bacterial cell-wall synthesis by inactivating transpeptidases on the inner surface of the bacterial cell membrane. After binding to the PBPs, Ampicilin acts as a structural analogue of acyl-D-alanyl-D-alanine, acylates the transpeptidase enzyme and thereby prevents the cross-linking of the peptidoglycan of the cell wall necessary for the growth of the bacterium.
Ampicillin sodium can be used as a selective agent in several types of isolation media. Ampicillin sodium is routinely used to select for cells containing the pcDNA3.1 and pEAK10 resistance plasmids in cell line A904L at an effective concentration of 50 μg/ml.

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