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ChemicalBook >> CAS DataBase List >> B-NICOTYRINE

B-NICOTYRINE

B-NICOTYRINE price.
  • $48 - $1732.5
  • Product name: B-NICOTYRINE
  • CAS: 487-19-4
  • MF: C10H10N2
  • MW: 158.2
  • EINECS:207-651-1
  • MDL Number:MFCD00468104
  • Synonyms:3-(1-methyl-2-pyrrolyl)pyridine ;3,2’-nicotyrine ;alpha-nicotyrine ;B-NICOTYRINE;(3-(1)-METHYLPYRROL-2-YL)-PYRIDINE;1-Methyl-2-(3-pyridinyl)-1H-pyrrole;BETA-NITROTYRINE;1-methyl-2-(3-pyridyl)pyrrole
Price18 Properties Safety Information Description
18 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • SynQuest Laboratories
  • TRC
Package
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 100MG
  • 1mg(solution)
  • 5mg(solution)
  • 10mg(solution)
  • 25mg(solution)
  • ManufacturerAK Scientific
  • Product number5655AF
  • Product description3-(1-Methyl-1H-pyrrol-2-yl)pyridine
  • Packaging10mg
  • Price$266
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0022088
  • Product description3-(1-METHYL-1H-PYRROL-2-YL)PYRIDINE 95.00%
  • Packaging10MG
  • Price$721.88
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0022088
  • Product description3-(1-METHYL-1H-PYRROL-2-YL)PYRIDINE 95.00%
  • Packaging100MG
  • Price$1732.5
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4647
  • Product descriptionβ-Nicotyrine
  • Packaging1mg(solution)
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4647
  • Product descriptionβ-Nicotyrine
  • Packaging5mg(solution)
  • Price$192
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4647
  • Product descriptionβ-Nicotyrine
  • Packaging10mg(solution)
  • Price$326
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4647
  • Product descriptionβ-Nicotyrine
  • Packaging25mg(solution)
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFN138662
  • Product descriptionBeta-Nicotyrine
  • Packaging1mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFN138662
  • Product descriptionBeta-Nicotyrine
  • Packaging2mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFN138662
  • Product descriptionBeta-Nicotyrine
  • Packaging5mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFN138662
  • Product descriptionBeta-Nicotyrine
  • Packaging10mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFN138662
  • Product descriptionBeta-Nicotyrine
  • Packaging25mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16333
  • Product descriptionβ-Nicotyrine ≥98%
  • Packaging1mg
  • Price$48
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16333
  • Product descriptionβ-Nicotyrine ≥98%
  • Packaging5mg
  • Price$119
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16333
  • Product descriptionβ-Nicotyrine ≥98%
  • Packaging10mg
  • Price$213
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16333
  • Product descriptionβ-Nicotyrine ≥98%
  • Packaging25mg
  • Price$414
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 5655AF 3-(1-Methyl-1H-pyrrol-2-yl)pyridine 10mg $266 2021-12-16 Buy
American Custom Chemicals Corporation CHM0022088 3-(1-METHYL-1H-PYRROL-2-YL)PYRIDINE 95.00% 10MG $721.88 2021-12-16 Buy
American Custom Chemicals Corporation CHM0022088 3-(1-METHYL-1H-PYRROL-2-YL)PYRIDINE 95.00% 100MG $1732.5 2021-12-16 Buy
ApexBio Technology C4647 β-Nicotyrine 1mg(solution) $96 2021-12-16 Buy
ApexBio Technology C4647 β-Nicotyrine 5mg(solution) $192 2021-12-16 Buy
ApexBio Technology C4647 β-Nicotyrine 10mg(solution) $326 2021-12-16 Buy
ApexBio Technology C4647 β-Nicotyrine 25mg(solution) $550 2021-12-16 Buy
Biosynth Carbosynth FN138662 Beta-Nicotyrine 1mg $100 2021-12-16 Buy
Biosynth Carbosynth FN138662 Beta-Nicotyrine 2mg $150 2021-12-16 Buy
Biosynth Carbosynth FN138662 Beta-Nicotyrine 5mg $200 2021-12-16 Buy
Biosynth Carbosynth FN138662 Beta-Nicotyrine 10mg $300 2021-12-16 Buy
Biosynth Carbosynth FN138662 Beta-Nicotyrine 25mg $600 2021-12-16 Buy
Cayman Chemical 16333 β-Nicotyrine ≥98% 1mg $48 2024-03-01 Buy
Cayman Chemical 16333 β-Nicotyrine ≥98% 5mg $119 2024-03-01 Buy
Cayman Chemical 16333 β-Nicotyrine ≥98% 10mg $213 2024-03-01 Buy
Cayman Chemical 16333 β-Nicotyrine ≥98% 25mg $414 2024-03-01 Buy
Next Last

Properties

Melting point :168-169 °C
Boiling point :78-80°C/0/15mm
Density :1.2410
refractive index :1.6057 (estimate)
storage temp. :-20°C Freezer, Under Inert Atmosphere
solubility :Chloroform (Slightly), Dichloromethane (Slightly), Ethyl Acetate (Slightly), Met
form :Oil
pka :pK1:4.76(+1) (25°C)
color :Pale Yellow to Brown to Dark Orange
Stability :Light, Air Sensitive
EPA Substance Registry System :Pyridine, 3-(1-methyl-1H-pyrrol-2-yl)- (487-19-4)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

Description

β-Nicotyrine is an alkaloid metabolite of nicotine as well as a major product of its pyrolysis. It binds comparably to two cytochrome P450 (CYP) isoforms, CYP2A6 and CYP2A13 (Kis = 7.5 and 5.6 μM, respectively), which are prominently involved in the metabolism of xenobiotics in the airways. However, β-nicotyrine appears to more effectively inactivate CYP2A6, leaving only 49% activity after a 10 minute exposure with 20 μM β-nicotyrine, as opposed to 87% remaining activity for CYP2A13 treated identically. Presumably through this effect, β-nicotyrine inhibits DNA strand breaks induced by the genotoxic tobacco metabolite (4-(methylnitrosamino)-1-(2-pyridyl)-1-butanone), which is bioactivated by CYP2A isoforms.

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