BAFILOMYCIN B1
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- $41 - $7969
- Product name: BAFILOMYCIN B1
- CAS: 88899-56-3
- MF: C44H65NO13
- MW: 815.99
- EINECS:
- MDL Number:MFCD33021141
- Synonyms:BAFILOMYCIN B1;BAFILOMYCIN B1 MONOHYDRATE FROM STREPTO- MYCES SPECIES;BafilomycinB1fromStreptomycesgriseus;bafilomycin b1from streptomyces sp.;hygrolidin,37-decarboxy-2-demethyl-37-(((2-hydroxy-5-oxo-1-cyclopenten-1-yl)am ;ino)carbonyl)-2-methoxy-24-methyl- ;37-De(carboxy)-2-demethyl-37-[[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]carbonyl]-2-methoxy-24-methylhygrolidin;2-Butenoic acid, 4-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-4-oxo-, (2R,4R,5S,6R)-tetrahydro-2-hydroxy-2-[(1S,2R,3S)-2-hydroxy-3-[(2R,3S,4E,6E,9S,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]-1-methylbutyl]-5-methyl-6-(1-methylethy...
36 prices
Selected condition：
Brand
- aablocks
- Adipogen Life Sciences
- Apolloscientific
- Biosynth
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- Thermo Scientific Chemicals
- TRC
- Usbiological
Package
- 100μg
- 100ug
- 1mg
- 2mg
- 2.5mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 1ml
- Manufactureraablocks
- Product numberAA00GRQ7
- Product descriptionBafilomycin B1 >98%
- Packaging1mg
- Price$374
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GRQ7
- Product descriptionBafilomycin B1 >98%
- Packaging5mg
- Price$1058
- Updated2026-05-28
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberBVT-0004-C100
- Product descriptionBafilomycinB1 ≥97%(HPLC)
- Packaging100μg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberBVT-0004-C100
- Product descriptionBafilomycin B1 ≥97%(HPLC)
- Packaging100μg
- Price$50
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberBVT-0004-M001
- Product descriptionBafilomycin B1 ≥97%(HPLC)
- Packaging1mg
- Price$90
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberBVT-0004-M005
- Product descriptionBafilomycin B1 ≥97%(HPLC)
- Packaging5mg
- Price$360
- Updated2026-05-06
- Buy
- ManufacturerApolloscientific
- Product numberBIBR1013
- Product descriptionBafilomycin B1
- Packaging1mg
- Price$157
- Updated2026-06-04
- Buy
- ManufacturerApolloscientific
- Product numberBIBR1013
- Product descriptionBafilomycin B1
- Packaging10mg
- Price$1094
- Updated2026-06-04
- Buy
- ManufacturerApolloscientific
- Product numberBIBR1013
- Product descriptionBafilomycin B1
- Packaging25mg
- Price$2419
- Updated2026-06-04
- Buy
- ManufacturerApolloscientific
- Product numberBIBR1013
- Product descriptionBafilomycin B1
- Packaging50mg
- Price$4392
- Updated2026-06-04
- Buy
- ManufacturerApolloscientific
- Product numberBIBR1013
- Product descriptionBafilomycin B1
- Packaging100mg
- Price$7969
- Updated2026-06-04
- Buy
- ManufacturerApolloscientific
- Product numberBIBR1013
- Product descriptionBafilomycin B1
- Packaging5mg
- Price$604
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberNDA89956
- Product descriptionBafilomycin B1
- Packaging1mg
- Price$731.6
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberNDA89956
- Product descriptionBafilomycin B1
- Packaging2mg
- Price$1282.7
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberNDA89956
- Product descriptionBafilomycin B1
- Packaging5mg
- Price$2068.9
- Updated2026-06-04
- Buy
- ManufacturerCayman Chemical
- Product number14005
- Product descriptionBafilomycin B1 ≥97%
- Packaging5mg
- Price$556
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00GRQ7 | Bafilomycin B1 >98% | 1mg | $374 | 2026-05-28 | Buy |
| aablocks | AA00GRQ7 | Bafilomycin B1 >98% | 5mg | $1058 | 2026-05-28 | Buy |
| Adipogen Life Sciences | BVT-0004-C100 | BafilomycinB1 ≥97%(HPLC) | 100μg | $50 | 2021-12-16 | Buy |
| Adipogen Life Sciences | BVT-0004-C100 | Bafilomycin B1 ≥97%(HPLC) | 100μg | $50 | 2026-05-06 | Buy |
| Adipogen Life Sciences | BVT-0004-M001 | Bafilomycin B1 ≥97%(HPLC) | 1mg | $90 | 2026-05-06 | Buy |
| Adipogen Life Sciences | BVT-0004-M005 | Bafilomycin B1 ≥97%(HPLC) | 5mg | $360 | 2026-05-06 | Buy |
| Apolloscientific | BIBR1013 | Bafilomycin B1 | 1mg | $157 | 2026-06-04 | Buy |
| Apolloscientific | BIBR1013 | Bafilomycin B1 | 10mg | $1094 | 2026-06-04 | Buy |
| Apolloscientific | BIBR1013 | Bafilomycin B1 | 25mg | $2419 | 2026-06-04 | Buy |
| Apolloscientific | BIBR1013 | Bafilomycin B1 | 50mg | $4392 | 2026-06-04 | Buy |
| Apolloscientific | BIBR1013 | Bafilomycin B1 | 100mg | $7969 | 2026-06-04 | Buy |
| Apolloscientific | BIBR1013 | Bafilomycin B1 | 5mg | $604 | 2026-06-04 | Buy |
| Biosynth | NDA89956 | Bafilomycin B1 | 1mg | $731.6 | 2026-06-04 | Buy |
| Biosynth | NDA89956 | Bafilomycin B1 | 2mg | $1282.7 | 2026-06-04 | Buy |
| Biosynth | NDA89956 | Bafilomycin B1 | 5mg | $2068.9 | 2026-06-04 | Buy |
| Cayman Chemical | 14005 | Bafilomycin B1 ≥97% | 5mg | $556 | 2026-04-30 | Buy |
Properties
storage temp. :−20°C
solubility :DMSO: Soluble; Methanol: Unstable
form :powder or crystals
color :faint yellow to yellow
BRN :4640118
Stability :Hygroscopic
InChIKey :KFUFLYSBMNNJTF-JUFZODOZSA-N
SMILES :C1(O)(C(C)C(O)C(C)C2OC(=O)C(OC)=CC(C)=CC(C(O)C(C)CC(C)=CC=CC2OC)C)OC(C(C)C(OC(=O)/C=C/C(=O)NC2=C(O)CCC2=O)C1)C(C)C |c:28,t:14,17,26|
solubility :DMSO: Soluble; Methanol: Unstable
form :powder or crystals
color :faint yellow to yellow
BRN :4640118
Stability :Hygroscopic
InChIKey :KFUFLYSBMNNJTF-JUFZODOZSA-N
SMILES :C1(O)(C(C)C(O)C(C)C2OC(=O)C(OC)=CC(C)=CC(C(O)C(C)CC(C)=CC=CC2OC)C)OC(C(C)C(OC(=O)/C=C/C(=O)NC2=C(O)CCC2=O)C1)C(C)C |c:28,t:14,17,26|
Safety Information
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| Signal word: | Danger | ||||||||||
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Description
The bafilomycins are fungal plecomacrolide antibiotics with a 16-membered lactone ring. They inhibit the growth of Gram-positive bacteria and fungi. Bafilomycin B1 is a selective, reversible inhibitor of vacuolar H+-ATPases (V-ATPases), blocking these proton pumps in mammalian, plant, or fungal cells with an IC50 value in the 4-400 nM range. It is at least 1,000-fold less potent at most other types of ATPases. When used at 100 nM, the related macrolide bafilomycin A1 blocks V-ATPase-mediated acidification of lysosomes during autophagy, preventing protein degradation. Remarkably, at only 1 nM, both bafilomycin A1 or B1 dramatically attenuate chloroquine-induced apoptosis of neurons without altering autophagy.More related product prices
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