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ChemicalBook >> CAS DataBase List >> BAY 11-7082

BAY 11-7082

BAY 11-7082 price.
  • $24 - $2304
  • Product name: BAY 11-7082
  • CAS: 19542-67-7
  • MF: C10H9NO2S
  • MW: 207.25
  • EINECS:
  • MDL Number:MFCD00712162
  • Synonyms:BAY 11-7082;BAY 11-7821;(E)-3-(4-METHYLPHENYLSULFONYL)-2-PROPENENITRILE;(E)-3-tosylacrylonitrile;(E)-3-(p-Toluenesulfonyl)acrylonitrile;BAY11-7082/BAY117082;BAY11-7082,BAY 117821;(2E)-3-[(4-METHYLPHENYL)SULFONYL]-2-PROPENENITRILE
41 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • 2x10mg
  • 25mg
  • 50mg
  • 10
  • 5mg
  • 10mg
  • 20mg
  • 100mg
  • 250mg
  • 1G
  • 5g
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-0013-M050
  • Product descriptionBAY 11-7082 ≥99%(NMR)
  • Packaging50mg
  • Price$280
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2252AH
  • Product description3-(Toluene-4-sulfonyl)-acrylonitrile
  • Packaging50mg
  • Price$131
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA107077
  • Product descriptionBAY 11-7082 98+%
  • Packaging5mg
  • Price$24
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA107077
  • Product descriptionBAY 11-7082 98+%
  • Packaging10mg
  • Price$31
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA107077
  • Product descriptionBAY 11-7082 98+%
  • Packaging250mg
  • Price$169
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4210
  • Product descriptionBay11-7821(BAY11-7082)
  • Packaging10mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4210
  • Product descriptionBay11-7821(BAY11-7082)
  • Packaging25mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4210
  • Product descriptionBay11-7821(BAY11-7082)
  • Packaging50mg
  • Price$190
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4210
  • Product descriptionBay11-7821(BAY11-7082)
  • Packaging100mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60021
  • Product descriptionBAY 11-7082
  • Packaging20mg
  • Price$218
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2132
  • Product descriptionBAY11-7082-BAY11-7821 99%
  • Packaging2x10mg
  • Price$143
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010266
  • Product descriptionBAY 11-7082 ≥98%
  • Packaging5mg
  • Price$49
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010266
  • Product descriptionBAY 11-7082 ≥98%
  • Packaging10mg
  • Price$92
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010266
  • Product descriptionBAY 11-7082 ≥98%
  • Packaging25mg
  • Price$216
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010266
  • Product descriptionBAY 11-7082 ≥98%
  • Packaging50mg
  • Price$380
  • Updated2024-03-01
  • Buy
  • ManufacturerChem-Impex
  • Product number42196
  • Product descriptionBAY11-7082,≥98%(HPLC) ≥98%(HPLC)
  • Packaging100MG
  • Price$37.27
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-0013-M050 BAY 11-7082 ≥99%(NMR) 50mg $280 2021-12-16 Buy
AK Scientific 2252AH 3-(Toluene-4-sulfonyl)-acrylonitrile 50mg $131 2021-12-16 Buy
Ambeed A107077 BAY 11-7082 98+% 5mg $24 2021-12-16 Buy
Ambeed A107077 BAY 11-7082 98+% 10mg $31 2021-12-16 Buy
Ambeed A107077 BAY 11-7082 98+% 250mg $169 2021-12-16 Buy
ApexBio Technology A4210 Bay11-7821(BAY11-7082) 10mg $60 2021-12-16 Buy
ApexBio Technology A4210 Bay11-7821(BAY11-7082) 25mg $120 2021-12-16 Buy
ApexBio Technology A4210 Bay11-7821(BAY11-7082) 50mg $190 2021-12-16 Buy
ApexBio Technology A4210 Bay11-7821(BAY11-7082) 100mg $300 2021-12-16 Buy
Arctom CFN60021 BAY 11-7082 20mg $218 2021-12-16 Buy
Axon Medchem Axon2132 BAY11-7082-BAY11-7821 99% 2x10mg $143 2021-12-16 Buy
Cayman Chemical 10010266 BAY 11-7082 ≥98% 5mg $49 2024-03-01 Buy
Cayman Chemical 10010266 BAY 11-7082 ≥98% 10mg $92 2024-03-01 Buy
Cayman Chemical 10010266 BAY 11-7082 ≥98% 25mg $216 2024-03-01 Buy
Cayman Chemical 10010266 BAY 11-7082 ≥98% 50mg $380 2024-03-01 Buy
Chem-Impex 42196 BAY11-7082,≥98%(HPLC) ≥98%(HPLC) 100MG $37.27 2021-12-16 Buy

Properties

Melting point :133-135℃
Boiling point :397.6±42.0 °C(Predicted)
Density :1.237±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :DMSO: 25 mg/mL, soluble
form :solid
color :white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P501 Dispose of contents/container to..…

Description

BAY 11-7082, a potential anti-inflammatory agent, is an irreversible inhibitor of IKK α and phosphorylation of cytokine-inducible IκBα (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-α, NFKBIA; IC50=10 μM). In intact HUVECs, it inhibits TNFα-induced phosphorylation and degradation of IκBa (NFKBIA) without affecting constitutive phosphorylation. Inhibition of ιBα phosphorylation and degradation results in the inactivation of NFκB and thereby inhibits the expression of endothelial-leukocyte adhesion molecules: E-selectin, VCAM-1 and ICAM-11. BAY 11-7082 has also demonstrated stimulation of the stress-activated protein kinases, p38 and JNK-1.

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