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ChemicalBook >> CAS DataBase List >> 1,9-Pyrazoloanthrone

1,9-Pyrazoloanthrone

$5 - $1390
Product name: 1,9-Pyrazoloanthrone
CAS: 129-56-6
MF: C14H8N2O
MW: 220.23
EINECS:204-955-6
MDL Number:MFCD00022289
Synonyms:Dibenzo[cd,g]indazol-6(2H)-one;Nsc75890;Wln: T C6665 1A p iv omnj;SP600125 >99%;JNK Inhibitor II, 1,9-Pyrazoloanthrone;c.i.70300 ;SAPK INHIBITOR I;SAPK INHIBITOR II

Price57 Properties Safety Information Description

57 prices

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Brand

AHH
AK Scientific
Alfa Aesar
Ambeed
American Custom Chemicals Corporation
ApexBio Technology
Arctom
Axon Medchem
Biorbyt Ltd
Cayman Chemical
Chem-Impex
ChemScene
Crysdot
CSNpharm
DC Chemicals
Medical Isotopes, Inc.
Sigma-Aldrich
TCI Chemical
Tocris
TRC
Usbiological

Package

5MG
10mg
20mg
25mg
50mg
100mg
200mg
10
50
250mg
500mg
1g
2g
2.5G
5g
10g
25g

ManufacturerAHH
Product numberMT-21875
Product description1,9-Pyrazoloanthrone 98%
Packaging5g
Price$388
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product numberJ51570
Product description1,9-Pyrazoloanthrone
Packaging5g
Price$55
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product numberK914
Product description1,9-Pyrazoloanthrone
Packaging5g
Price$74
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product numberJ51570
Product description1,9-Pyrazoloanthrone
Packaging10g
Price$90
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product numberJ51570
Product description1,9-Pyrazoloanthrone
Packaging25g
Price$170
Updated2021-12-16
Buy

ManufacturerAlfa Aesar
Product numberJ67272
Product descriptionSP600125 99%
Packaging50mg
Price$126
Updated2023-06-20
Buy

ManufacturerAlfa Aesar
Product numberJ67272
Product descriptionSP600125 99%
Packaging100mg
Price$217
Updated2023-06-20
Buy

ManufacturerAmbeed
Product numberA155219
Product descriptionSP-600125 98+%
Packaging10mg
Price$5
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA155219
Product descriptionSP-600125 98+%
Packaging50mg
Price$16
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA155219
Product descriptionSP-600125 98+%
Packaging100mg
Price$30
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA155219
Product descriptionSP-600125 98+%
Packaging250mg
Price$45
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA155219
Product descriptionSP-600125 98+%
Packaging1g
Price$110
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA155219
Product descriptionSP-600125 98+%
Packaging5g
Price$186
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberKIN0000236
Product description1,9-PYRAZOLOANTHRONE 95.00%
Packaging5MG
Price$501
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberKIN0000236
Product description1,9-PYRAZOLOANTHRONE 95.00%
Packaging1G
Price$692.46
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberKIN0000236
Product description1,9-PYRAZOLOANTHRONE 95.00%
Packaging2.5G
Price$932.6
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
AHH	MT-21875	1,9-Pyrazoloanthrone 98%	5g	$388	2021-12-16	Buy
AK Scientific	J51570	1,9-Pyrazoloanthrone	5g	$55	2021-12-16	Buy
AK Scientific	K914	1,9-Pyrazoloanthrone	5g	$74	2021-12-16	Buy
AK Scientific	J51570	1,9-Pyrazoloanthrone	10g	$90	2021-12-16	Buy
AK Scientific	J51570	1,9-Pyrazoloanthrone	25g	$170	2021-12-16	Buy
Alfa Aesar	J67272	SP600125 99%	50mg	$126	2023-06-20	Buy
Alfa Aesar	J67272	SP600125 99%	100mg	$217	2023-06-20	Buy
Ambeed	A155219	SP-600125 98+%	10mg	$5	2021-12-16	Buy
Ambeed	A155219	SP-600125 98+%	50mg	$16	2021-12-16	Buy
Ambeed	A155219	SP-600125 98+%	100mg	$30	2021-12-16	Buy
Ambeed	A155219	SP-600125 98+%	250mg	$45	2021-12-16	Buy
Ambeed	A155219	SP-600125 98+%	1g	$110	2021-12-16	Buy
Ambeed	A155219	SP-600125 98+%	5g	$186	2021-12-16	Buy
American Custom Chemicals Corporation	KIN0000236	1,9-PYRAZOLOANTHRONE 95.00%	5MG	$501	2021-12-16	Buy
American Custom Chemicals Corporation	KIN0000236	1,9-PYRAZOLOANTHRONE 95.00%	1G	$692.46	2021-12-16	Buy
American Custom Chemicals Corporation	KIN0000236	1,9-PYRAZOLOANTHRONE 95.00%	2.5G	$932.6	2021-12-16	Buy

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Properties

Melting point :281~282℃
Boiling point :361.16°C (rough estimate)
Density :1.1702 (rough estimate)
refractive index :1.5910 (estimate)
storage temp. :2-8°C
solubility :H₂O: insoluble
form :Yellowish orange solid
pka :11.75±0.20(Predicted)
color :yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months
InChIKey :ACPOUJIDANTYHO-UHFFFAOYSA-N
CAS DataBase Reference :129-56-6(CAS DataBase Reference)
EPA Substance Registry System :Anthra[1,9-cd]pyrazol-6(2H)-one (129-56-6)

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405	Store locked up.

Description

SP 600125 is a potent and reversible inhibitor of JNK1-3 with an IC50 value of 0.11 ?M.1 It is cell-permeable and dose-dependently inhibits c-Jun phosphorylation in cells, blocking the expression of COX-2 and TNF-α in monocytes and IL-10, TNF-α, and IFN-γ in T-cells. SP 600125 also prevents apoptosis in many cell types, including B-cells, and inhibits autophagy in HeLa cells. Competitively and reversibly inhibits JNK1, 2 and 3 (IC50 = 40 - 90 nM) with negligible activity at ERK2, p38β and a range of enzymes (IC50 > 10 ?M). Active in vivo. Shown to have reduced selectivity over other protein kinases under certain conditions. Protects renal tubular epithelial cells against ischemia/reperfusion-induced apoptosis. Prevents BMP9-induced osteogenic differentiation of MSCs.

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Suppliers and manufacturers

Hebei Mojin Biotechnology Co., Ltd

$0.00 /25KG
1,9-Pyrazoloanthrone CAS:129-56-6

Henan Bao Enluo International TradeCo.，LTD

$50.00 /1kg
SP 600125 CAS:129-56-6

Hebei Guanlang Biotechnology Co., Ltd.

$10.00 /1PCS
1,9-Pyrazoloanthrone CAS:129-56-6

career henan chemical co

$1.00 /1g
1,9-Pyrazoloanthrone CAS:129-56-6

Shaanxi Dideu Medichem Co. Ltd

$668.00 /1KG
1,9-Pyrazoloanthrone CAS:129-56-6

ATK CHEMICAL COMPANY LIMITED

Biochempartner

Hubei Jusheng Technology Co.,Ltd.

Alchem Pharmtech,Inc.

CONIER CHEM AND PHARMA LIMITED

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1,9-Pyrazoloanthrone

Properties

Safety Information

Description

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Suppliers and manufacturers