BIIB-021
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- $19 - $2520
- Product name: BIIB-021
- CAS: 848695-25-0
- MF: C14H15ClN6O
- MW: 318.76
- EINECS:812-781-2
- MDL Number:MFCD15528939
- Synonyms:CNF2024;9-[2-(2,2-diMethyl-propylaMino)ethyl]-8-(2-iodo-5-Methoxy-phenylsulfanyl)-9H-purin-6-ylaMine;CNF-2024EC102;9H-Purin-2-aMine, 6-chloro-9-[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]-;BIIB-021;BIIB021/CNF2024;6-Chloro-9-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]-9H-purin-2-amine;6-CHLORO-9-[(4-METHOXY-3,5-DIMETHYLPYRIDIN-2-YL)METHYL]PURIN-2-AMINE
67 prices
Selected condition：
Brand
- aablocks
- Absolute Chiral
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Tocris
- TRC
- Usbiological
Package
- 10.00mg
- 50
- 10mM(in 1mL DMSO)
- 10mM(in1mLDMSO)
- 10
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100.00mg
- 100mg
- 200mg
- 250mg
- 250.00mg
- 500MG
- 1g
- 2g
- Manufactureraablocks
- Product numberAA008FY8
- Product descriptionBIIB021 98%
- Packaging1mg
- Price$19
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008FY8
- Product descriptionBIIB021 98%
- Packaging5mg
- Price$27
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008FY8
- Product descriptionBIIB021 98%
- Packaging10mg
- Price$36
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008FY8
- Product descriptionBIIB021 ≥98%
- Packaging25mg
- Price$60
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008FY8
- Product descriptionBIIB021 95%
- Packaging100mg
- Price$120
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008FY8
- Product descriptionBIIB021 95%
- Packaging250mg
- Price$232
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008FY8
- Product descriptionBIIB021 95%
- Packaging1g
- Price$569
- Updated2026-05-28
- Buy
- ManufacturerAbsolute Chiral
- Product numberD1070-00-N
- Product description6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine 95%
- Packaging250mg
- Price$198
- Updated2026-05-23
- Buy
- ManufacturerAbsolute Chiral
- Product numberD1070-00-N
- Product description6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine 95%
- Packaging100mg
- Price$98
- Updated2026-05-23
- Buy
- ManufacturerAK Scientific
- Product numberX7555
- Product description6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine
- Packaging1g
- Price$1593
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000692
- Product descriptionBIIB-021 95.00%
- Packaging500MG
- Price$1527.5
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000692
- Product descriptionBIIB-021 95.00%
- Packaging5MG
- Price$447
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000692
- Product descriptionBIIB-021 95.00%
- Packaging10MG
- Price$468
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000692
- Product descriptionBIIB-021 95.00%
- Packaging25MG
- Price$508
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4058
- Product descriptionBIIB021
- Packaging50mg
- Price$210
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA4058
- Product descriptionBIIB021
- Packaging100mg
- Price$320
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA008FY8 | BIIB021 98% | 1mg | $19 | 2026-05-28 | Buy |
| aablocks | AA008FY8 | BIIB021 98% | 5mg | $27 | 2026-05-28 | Buy |
| aablocks | AA008FY8 | BIIB021 98% | 10mg | $36 | 2026-05-28 | Buy |
| aablocks | AA008FY8 | BIIB021 ≥98% | 25mg | $60 | 2026-05-28 | Buy |
| aablocks | AA008FY8 | BIIB021 95% | 100mg | $120 | 2026-05-28 | Buy |
| aablocks | AA008FY8 | BIIB021 95% | 250mg | $232 | 2026-05-28 | Buy |
| aablocks | AA008FY8 | BIIB021 95% | 1g | $569 | 2026-05-28 | Buy |
| Absolute Chiral | D1070-00-N | 6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine 95% | 250mg | $198 | 2026-05-23 | Buy |
| Absolute Chiral | D1070-00-N | 6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine 95% | 100mg | $98 | 2026-05-23 | Buy |
| AK Scientific | X7555 | 6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine | 1g | $1593 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000692 | BIIB-021 95.00% | 500MG | $1527.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000692 | BIIB-021 95.00% | 5MG | $447 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000692 | BIIB-021 95.00% | 10MG | $468 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000692 | BIIB-021 95.00% | 25MG | $508 | 2021-12-16 | Buy |
| ApexBio Technology | A4058 | BIIB021 | 50mg | $210 | 2026-05-06 | Buy |
| ApexBio Technology | A4058 | BIIB021 | 100mg | $320 | 2026-05-06 | Buy |
Properties
Melting point :192-193℃
Boiling point :588.5±60.0 °C(Predicted)
Density :1.50
storage temp. :-20°C
solubility :Soluble in DMSO (>25 mg/ml)
form :solid
pka :6.07±0.40(Predicted)
color :White
Stability :Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 montha.
InChI :InChI=1S/C14H15ClN6O/c1-7-4-17-9(8(2)11(7)22-3)5-21-6-18-10-12(15)19-14(16)20-13(10)21/h4,6H,5H2,1-3H3,(H2,16,19,20)
InChIKey :QULDDKSCVCJTPV-UHFFFAOYSA-N
SMILES :N1C2C(=NC(N)=NC=2Cl)N(CC2=NC=C(C)C(OC)=C2C)C=1
Boiling point :588.5±60.0 °C(Predicted)
Density :1.50
storage temp. :-20°C
solubility :Soluble in DMSO (>25 mg/ml)
form :solid
pka :6.07±0.40(Predicted)
color :White
Stability :Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 montha.
InChI :InChI=1S/C14H15ClN6O/c1-7-4-17-9(8(2)11(7)22-3)5-21-6-18-10-12(15)19-14(16)20-13(10)21/h4,6H,5H2,1-3H3,(H2,16,19,20)
InChIKey :QULDDKSCVCJTPV-UHFFFAOYSA-N
SMILES :N1C2C(=NC(N)=NC=2Cl)N(CC2=NC=C(C)C(OC)=C2C)C=1
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
BIIB021 is a potent, orally-available inhibitor of Hsp90 (Ki = 1.7 nM) that induces the degradation of oncoproteins, including HER2 (EC50 = 38 nM), while up-regulating the expression of Hsp70 and Hsp27. It is cytotoxic to cancer cells and, when administered orally to mice, inhibits growth of xenograft tumors. BIIB021 suppresses growth in various lymphoma cells but not in normal lymphocytes and induces apoptosis in a myelodysplastic syndrome cell line.Related product price
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Suppliers and manufacturers
Beijing Yisiyan Technology Research Center
Shanghai Boyle Chemical Co., Ltd.
J & K SCIENTIFIC LTD.
Chembest Research Laboratories Limited
Nanjing Chemlin Chemical Co., Ltd
Chemsky (shanghai) International Co.,Ltd
Jinan Trio PharmaTech Co., Ltd.
Dalian Meilun Biotech Co., Ltd.
Shanghai civi chemical technology co.,Ltd
Nanjing JinruiJiuAn Biotechnology Co., Ltd.