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ChemicalBook >> CAS DataBase List >> BMS-8

BMS-8

BMS-8 price.
  • $25 - $542
  • Product name: BMS-8
  • CAS: 1675201-90-7
  • MF: C27H28BrNO3
  • MW: 494.42
  • EINECS:
  • MDL Number:MFCD31714164
  • Synonyms:BMS-8;2-Piperidinecarboxylic acid, 1-[[3-bromo-4-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]phenyl]methyl]-;1-(3-bromo-4-((2-methylbiphenyl-3-yl)methoxy)benzyl)piperidine-2-carboxylic acid;PPI,BMS 8,BMS8,inhibit,BMS-8,Inhibitor,PD-L1,PD-1;1-(3-Bromo-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylic acid;BMS-8, 10 mM in DMSO;1-(3-Bromo-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylic acid , BMS-8
8 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
  • TRC
Package
  • 500μg
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerAK Scientific
  • Product number2101EF
  • Product description1-[[3-Bromo-4-[(2-methyl-3-phenylphenyl)methoxy]phenyl]methyl]piperidine-2-carboxylicacid
  • Packaging1mg
  • Price$164
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2101EF
  • Product description1-[[3-Bromo-4-[(2-methyl-3-phenylphenyl)methoxy]phenyl]methyl]piperidine-2-carboxylicacid
  • Packaging5mg
  • Price$370
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number22355
  • Product descriptionBMS-8 ≥98%
  • Packaging500μg
  • Price$25
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number22355
  • Product descriptionBMS-8 ≥98%
  • Packaging1mg
  • Price$26
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22355
  • Product descriptionBMS-8 ≥98%
  • Packaging5mg
  • Price$122
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22355
  • Product descriptionBMS-8 ≥98%
  • Packaging10mg
  • Price$230
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22355
  • Product descriptionBMS-8 ≥98%
  • Packaging25mg
  • Price$542
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberB695180
  • Product descriptionBMS-8
  • Packaging1mg
  • Price$125
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2101EF 1-[[3-Bromo-4-[(2-methyl-3-phenylphenyl)methoxy]phenyl]methyl]piperidine-2-carboxylicacid 1mg $164 2021-12-16 Buy
AK Scientific 2101EF 1-[[3-Bromo-4-[(2-methyl-3-phenylphenyl)methoxy]phenyl]methyl]piperidine-2-carboxylicacid 5mg $370 2021-12-16 Buy
Cayman Chemical 22355 BMS-8 ≥98% 500μg $25 2021-12-16 Buy
Cayman Chemical 22355 BMS-8 ≥98% 1mg $26 2024-03-01 Buy
Cayman Chemical 22355 BMS-8 ≥98% 5mg $122 2024-03-01 Buy
Cayman Chemical 22355 BMS-8 ≥98% 10mg $230 2024-03-01 Buy
Cayman Chemical 22355 BMS-8 ≥98% 25mg $542 2024-03-01 Buy
TRC B695180 BMS-8 1mg $125 2021-12-16 Buy

Properties

Boiling point :616.9±55.0 °C(Predicted)
Density :1.334±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Methanol: slightly soluble
form :A crystalline solid
pka :2.35±0.20(Predicted)
color :White to off-white
InChIKey :QRXBPPWUGITQLE-UHFFFAOYSA-N
SMILES :N1(CC2=CC=C(OCC3C=CC=C(C4=CC=CC=C4)C=3C)C(Br)=C2)CCCCC1C(O)=O

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P501 Dispose of contents/container to..…

Description

BMS-8 is a small molecule inhibitor of the protein-protein interaction between programmed death protein 1 (PD-1) and its ligand programmed cell death ligand 1 (PD-L1) with an IC50 value of 146 nM in a homogeneous time-resolved fluorescence (HTRF) binding assay.