BORRELIDIN
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- $80 - $2393
- Product name: BORRELIDIN
- CAS: 7184-60-3
- MF: C28H43NO6
- MW: 489.64
- EINECS:
- MDL Number:MFCD08276914
- Synonyms:2-(7-CYANO-8,16-DIHYDROXY-9,11,13,15-TETRAMETHYL-18-OXOOXACYCLOOCTADECA-4,6-DIEN-2-YL)-CYCLOPENTANECARBOXYLIC ACID;BORRELIDIN;BORRELIDINE;2-(7-Cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxo-1-oxacyclooctadeca-4,6-dien-2-yl)cyclopentane-1-carboxylic acid;Aids128115;Aids-128115;Cyclopentanecarboxylic acid, 2-(7-cyano-8, 16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4, 6-dien-2-yl)-;Quinquangulin K 031
33 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 500ug
- 10mM*1mLinEthanol(Solution)
- 1
- 500μg
- 1mg
- 5mg
- 10mg
- 25mg
- 500??g
- ManufacturerAdipogen Life Sciences
- Product numberBVT-0098-C500
- Product descriptionBorrelidin ≥98%(HPLC)
- Packaging500μg
- Price$80
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberBVT-0098-M001
- Product descriptionBorrelidin ≥98%(HPLC)
- Packaging1mg
- Price$120
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberBVT-0098-M005
- Product descriptionBorrelidin ≥98%(HPLC)
- Packaging5mg
- Price$360
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberBVT-0098-M005
- Product descriptionBorrelidin ≥98%(HPLC)
- Packaging5mg
- Price$400
- Updated2026-05-06
- Buy
- ManufacturerAK Scientific
- Product number8443AJ
- Product descriptionBorrelidin
- Packaging5mg
- Price$860
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number8443AJ
- Product descriptionBorrelidin
- Packaging10mg
- Price$1332
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7699
- Product descriptionBorrelidin
- Packaging500ug
- Price$349
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7699
- Product descriptionBorrelidin
- Packaging1mg
- Price$693
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7699
- Product descriptionBorrelidin
- Packaging500ug
- Price$410
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7699
- Product descriptionBorrelidin
- Packaging1mg
- Price$559
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-N6742
- Product descriptionBorrelidin 99.0%
- Packaging1mg
- Price$615
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-N6742
- Product descriptionBorrelidin 99.0%
- Packaging500??g
- Price$363
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-N6742
- Product descriptionBorrelidin 99.0%
- Packaging10mM*1mLinEthanol(Solution)
- Price$922
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-N6742
- Product descriptionBorrelidin 99.0%
- Packaging10mg
- Price$1197
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-N6742
- Product descriptionBorrelidin 99.0%
- Packaging5mg
- Price$855
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-N6742
- Product descriptionBorrelidin 99.0%
- Packaging25mg
- Price$2393
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | BVT-0098-C500 | Borrelidin ≥98%(HPLC) | 500μg | $80 | 2026-05-06 | Buy |
| Adipogen Life Sciences | BVT-0098-M001 | Borrelidin ≥98%(HPLC) | 1mg | $120 | 2026-05-06 | Buy |
| Adipogen Life Sciences | BVT-0098-M005 | Borrelidin ≥98%(HPLC) | 5mg | $360 | 2021-12-16 | Buy |
| Adipogen Life Sciences | BVT-0098-M005 | Borrelidin ≥98%(HPLC) | 5mg | $400 | 2026-05-06 | Buy |
| AK Scientific | 8443AJ | Borrelidin | 5mg | $860 | 2021-12-16 | Buy |
| AK Scientific | 8443AJ | Borrelidin | 10mg | $1332 | 2021-12-16 | Buy |
| ApexBio Technology | B7699 | Borrelidin | 500ug | $349 | 2026-05-06 | Buy |
| ApexBio Technology | B7699 | Borrelidin | 1mg | $693 | 2021-12-16 | Buy |
| ApexBio Technology | B7699 | Borrelidin | 500ug | $410 | 2021-12-16 | Buy |
| ApexBio Technology | B7699 | Borrelidin | 1mg | $559 | 2026-05-06 | Buy |
| Arctom | HY-N6742 | Borrelidin 99.0% | 1mg | $615 | 2026-05-26 | Buy |
| Arctom | HY-N6742 | Borrelidin 99.0% | 500??g | $363 | 2026-05-26 | Buy |
| Arctom | HY-N6742 | Borrelidin 99.0% | 10mM*1mLinEthanol(Solution) | $922 | 2026-05-26 | Buy |
| Arctom | HY-N6742 | Borrelidin 99.0% | 10mg | $1197 | 2026-05-26 | Buy |
| Arctom | HY-N6742 | Borrelidin 99.0% | 5mg | $855 | 2026-05-26 | Buy |
| Arctom | HY-N6742 | Borrelidin 99.0% | 25mg | $2393 | 2026-05-26 | Buy |
Properties
Melting point :143-145℃
Boiling point :584.45°C (rough estimate)
Density :1.1362 (rough estimate)
refractive index :1.6290 (estimate)
storage temp. :−20°C
solubility :DMSO: 1 mg/mL
form :White to off-white powder.
pka :4.56±0.40(Predicted)
color :Off-white
biological source :Streptomyces parvulus
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKey :OJCKRNPLOZHAOU-UGKRXNSESA-N
SMILES :[H][C@]1(CCC[C@H]1C(O)=O)[C@@H]2C\C=C\C=C(C#N)[C@H](O)[C@@H](C)C[C@H](C)C[C@H](C)C[C@H](C)[C@@H](O)CC(=O)O2
Boiling point :584.45°C (rough estimate)
Density :1.1362 (rough estimate)
refractive index :1.6290 (estimate)
storage temp. :−20°C
solubility :DMSO: 1 mg/mL
form :White to off-white powder.
pka :4.56±0.40(Predicted)
color :Off-white
biological source :Streptomyces parvulus
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKey :OJCKRNPLOZHAOU-UGKRXNSESA-N
SMILES :[H][C@]1(CCC[C@H]1C(O)=O)[C@@H]2C\C=C\C=C(C#N)[C@H](O)[C@@H](C)C[C@H](C)C[C@H](C)C[C@H](C)[C@@H](O)CC(=O)O2
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Borrelidin is a secondary metabolite produced by Streptomyces and other bacteria. It displays potent antiangiogenic activity, preventing tube formation in rat aorta explants (IC50 = 0.8 nM) and inducing apoptosis in endothelial cells. Borrelidin also alters the splicing of VEGF mRNA, producing an antiangiogenic isoform of the growth factor. It has long been known as a powerful inhibitor of both eukaryotic and bacterial threonyl tRNA synthetase. Borrelidin is also an effective anti-malarial drug, as it kills P. falciparum with an IC50 value of 1.8 nM. At higher doses, it inhibits cyclin-dependent kinase in yeast (IC50 = 24 μM), resulting in growth arrest in the G1 phase.More related product prices
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Suppliers and manufacturers
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