BORRELIDIN
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- $80 - $5474
- Product name: BORRELIDIN
- CAS: 7184-60-3
- MF: C28H43NO6
- MW: 489.64
- EINECS:
- MDL Number:MFCD08276914
- Synonyms:2-(7-CYANO-8,16-DIHYDROXY-9,11,13,15-TETRAMETHYL-18-OXOOXACYCLOOCTADECA-4,6-DIEN-2-YL)-CYCLOPENTANECARBOXYLIC ACID;BORRELIDIN;BORRELIDINE;2-(7-Cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxo-1-oxacyclooctadeca-4,6-dien-2-yl)cyclopentane-1-carboxylic acid;Aids128115;Aids-128115;Cyclopentanecarboxylic acid, 2-(7-cyano-8, 16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4, 6-dien-2-yl)-;Quinquangulin K 031
49 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- ApexBio Technology
- Apolloscientific
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 0.5mg
- 500ug
- 1
- 500μg
- 1mg
- 2mg
- 5mg
- 10mg
- 50mg
- 500??g
- 25mg
- 10mM*1mLinEthanol(Solution)
- Manufactureraablocks
- Product numberAA005PKK
- Product descriptionBorrelidin ≥98%
- Packaging1mg
- Price$135
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005PKK
- Product descriptionBorrelidin 99%
- Packaging5mg
- Price$356
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005PKK
- Product descriptionBorrelidin 99%
- Packaging10mg
- Price$497
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberAD261951
- Product descriptionBorrelidin 97%
- Packaging1MG
- Price$300
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberAD261951
- Product descriptionBorrelidin 97%
- Packaging5MG
- Price$1050
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberBVT-0098-M005
- Product descriptionBorrelidin ≥98%(HPLC)
- Packaging5mg
- Price$400
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberBVT-0098-M001
- Product descriptionBorrelidin ≥98%(HPLC)
- Packaging1mg
- Price$120
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberBVT-0098-C500
- Product descriptionBorrelidin ≥98%(HPLC)
- Packaging500μg
- Price$80
- Updated2026-05-06
- Buy
- ManufacturerAK Scientific
- Product number8443AJ
- Product descriptionBorrelidin
- Packaging10mg
- Price$1332
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number8443AJ
- Product descriptionBorrelidin
- Packaging5mg
- Price$860
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7699
- Product descriptionBorrelidin
- Packaging1mg
- Price$559
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7699
- Product descriptionBorrelidin
- Packaging500ug
- Price$349
- Updated2026-05-06
- Buy
- ManufacturerApolloscientific
- Product numberBIB3043
- Product descriptionBorrelidin
- Packaging5mg
- Price$774
- Updated2026-06-04
- Buy
- ManufacturerApolloscientific
- Product numberBIB3043
- Product descriptionBorrelidin
- Packaging10mg
- Price$1392
- Updated2026-06-04
- Buy
- ManufacturerApolloscientific
- Product numberBIB3043
- Product descriptionBorrelidin
- Packaging1mg
- Price$209
- Updated2026-06-04
- Buy
- ManufacturerApolloscientific
- Product numberBIB3043
- Product descriptionBorrelidin
- Packaging25mg
- Price$3041
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA005PKK | Borrelidin ≥98% | 1mg | $135 | 2026-05-28 | Buy |
| aablocks | AA005PKK | Borrelidin 99% | 5mg | $356 | 2026-05-28 | Buy |
| aablocks | AA005PKK | Borrelidin 99% | 10mg | $497 | 2026-05-28 | Buy |
| ACHEMBLOCK | AD261951 | Borrelidin 97% | 1MG | $300 | 2026-05-27 | Buy |
| ACHEMBLOCK | AD261951 | Borrelidin 97% | 5MG | $1050 | 2026-05-27 | Buy |
| Adipogen Life Sciences | BVT-0098-M005 | Borrelidin ≥98%(HPLC) | 5mg | $400 | 2026-05-06 | Buy |
| Adipogen Life Sciences | BVT-0098-M001 | Borrelidin ≥98%(HPLC) | 1mg | $120 | 2026-05-06 | Buy |
| Adipogen Life Sciences | BVT-0098-C500 | Borrelidin ≥98%(HPLC) | 500μg | $80 | 2026-05-06 | Buy |
| AK Scientific | 8443AJ | Borrelidin | 10mg | $1332 | 2021-12-16 | Buy |
| AK Scientific | 8443AJ | Borrelidin | 5mg | $860 | 2021-12-16 | Buy |
| ApexBio Technology | B7699 | Borrelidin | 1mg | $559 | 2026-05-06 | Buy |
| ApexBio Technology | B7699 | Borrelidin | 500ug | $349 | 2026-05-06 | Buy |
| Apolloscientific | BIB3043 | Borrelidin | 5mg | $774 | 2026-06-04 | Buy |
| Apolloscientific | BIB3043 | Borrelidin | 10mg | $1392 | 2026-06-04 | Buy |
| Apolloscientific | BIB3043 | Borrelidin | 1mg | $209 | 2026-06-04 | Buy |
| Apolloscientific | BIB3043 | Borrelidin | 25mg | $3041 | 2026-06-04 | Buy |
Properties
Melting point :143-145℃
Boiling point :584.45°C (rough estimate)
Density :1.1362 (rough estimate)
refractive index :1.6290 (estimate)
storage temp. :−20°C
solubility :DMSO: 1 mg/mL
form :White to off-white powder.
pka :4.56±0.40(Predicted)
color :Off-white
biological source :Streptomyces parvulus
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKey :OJCKRNPLOZHAOU-UGKRXNSESA-N
SMILES :[H][C@]1(CCC[C@H]1C(O)=O)[C@@H]2C\C=C\C=C(C#N)[C@H](O)[C@@H](C)C[C@H](C)C[C@H](C)C[C@H](C)[C@@H](O)CC(=O)O2
Boiling point :584.45°C (rough estimate)
Density :1.1362 (rough estimate)
refractive index :1.6290 (estimate)
storage temp. :−20°C
solubility :DMSO: 1 mg/mL
form :White to off-white powder.
pka :4.56±0.40(Predicted)
color :Off-white
biological source :Streptomyces parvulus
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKey :OJCKRNPLOZHAOU-UGKRXNSESA-N
SMILES :[H][C@]1(CCC[C@H]1C(O)=O)[C@@H]2C\C=C\C=C(C#N)[C@H](O)[C@@H](C)C[C@H](C)C[C@H](C)C[C@H](C)[C@@H](O)CC(=O)O2
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
| Hazard statements: |
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Description
Borrelidin is a secondary metabolite produced by Streptomyces and other bacteria. It displays potent antiangiogenic activity, preventing tube formation in rat aorta explants (IC50 = 0.8 nM) and inducing apoptosis in endothelial cells. Borrelidin also alters the splicing of VEGF mRNA, producing an antiangiogenic isoform of the growth factor. It has long been known as a powerful inhibitor of both eukaryotic and bacterial threonyl tRNA synthetase. Borrelidin is also an effective anti-malarial drug, as it kills P. falciparum with an IC50 value of 1.8 nM. At higher doses, it inhibits cyclin-dependent kinase in yeast (IC50 = 24 μM), resulting in growth arrest in the G1 phase.More related product prices
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