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ChemicalBook >> CAS DataBase List >> Bortezomib

Bortezomib

Bortezomib price.
  • $16 - $1980
  • Product name: Bortezomib
  • CAS: 179324-69-7
  • MF: C19H25BN4O4
  • MW: 384.24
  • EINECS:605-854-3
  • MDL Number:MFCD09056737
  • Synonyms:Boronic acid, B-[(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]bu;MG-341 PS-341;BortezoMib Base;bortezoMib(other);MLM341;BortezoMib R;VELCADE(BORTEZOMIB);Boronic acid, B-[(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]-
60 prices
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  • Adipogen Life Sciences
  • AK Scientific
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  • American Custom Chemicals Corporation
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  • 10mM(in 1mL DMSO)
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  • 1g
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3602-M005
  • Product descriptionBortezomib ≥97%(NMR)
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberQ425
  • Product descriptionBortezomib
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ60378
  • Product descriptionBortezomib, 99%
  • Packaging10mg
  • Price$250
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ60378
  • Product descriptionBortezomib, 99%
  • Packaging25mg
  • Price$437
  • Updated2024-03-01
  • Buy
  • ManufacturerAlichem
  • Product number179324697
  • Product description((R)-3-Nethyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronicacid
  • Packaging250mg
  • Price$202.65
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number179324697
  • Product description((R)-3-Nethyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronicacid
  • Packaging1g
  • Price$468.3
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA385479
  • Product description((R)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronicacid 98+%
  • Packaging5mg
  • Price$16
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA385479
  • Product description((R)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronicacid 98+%
  • Packaging10mg
  • Price$21
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA385479
  • Product description((R)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronicacid 98+%
  • Packaging50mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA385479
  • Product description((R)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronicacid 98+%
  • Packaging100mg
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA385479
  • Product description((R)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronicacid 98+%
  • Packaging250mg
  • Price$73
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA385479
  • Product description((R)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronicacid 98+%
  • Packaging1g
  • Price$223
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0001750
  • Product descriptionBORTEZOMIB 95.00%
  • Packaging5MG
  • Price$506
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0001750
  • Product descriptionBORTEZOMIB 95.00%
  • Packaging100MG
  • Price$1000
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0001750
  • Product descriptionBORTEZOMIB 95.00%
  • Packaging1G
  • Price$1904.7
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2614
  • Product descriptionBortezomib(PS-341)
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-3602-M005 Bortezomib ≥97%(NMR) 5mg $50 2021-12-16 Buy
AK Scientific Q425 Bortezomib 5mg $60 2021-12-16 Buy
Alfa Aesar J60378 Bortezomib, 99% 10mg $250 2024-03-01 Buy
Alfa Aesar J60378 Bortezomib, 99% 25mg $437 2024-03-01 Buy
Alichem 179324697 ((R)-3-Nethyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronicacid 250mg $202.65 2021-12-16 Buy
Alichem 179324697 ((R)-3-Nethyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronicacid 1g $468.3 2021-12-16 Buy
Ambeed A385479 ((R)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronicacid 98+% 5mg $16 2021-12-16 Buy
Ambeed A385479 ((R)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronicacid 98+% 10mg $21 2021-12-16 Buy
Ambeed A385479 ((R)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronicacid 98+% 50mg $30 2021-12-16 Buy
Ambeed A385479 ((R)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronicacid 98+% 100mg $39 2021-12-16 Buy
Ambeed A385479 ((R)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronicacid 98+% 250mg $73 2021-12-16 Buy
Ambeed A385479 ((R)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronicacid 98+% 1g $223 2021-12-16 Buy
American Custom Chemicals Corporation API0001750 BORTEZOMIB 95.00% 5MG $506 2021-12-16 Buy
American Custom Chemicals Corporation API0001750 BORTEZOMIB 95.00% 100MG $1000 2021-12-16 Buy
American Custom Chemicals Corporation API0001750 BORTEZOMIB 95.00% 1G $1904.7 2021-12-16 Buy
ApexBio Technology A2614 Bortezomib(PS-341) 1unit $28 2021-12-16 Buy

Properties

Melting point :122-124°C
Density :1.214
RTECS :ED7771666
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :Soluble in chloroform, dimethyl sulfoxide, ethanol and methanol.
form :solid
pka :9.66±0.43(Predicted)
color :White
Stability :Hygroscopic and Moisture Sensitive
CAS DataBase Reference :179324-69-7(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H310 Fatal in contact with skin Acute toxicity,dermal Category 1, 2 Danger GHS hazard pictograms P262, P264, P270, P280, P302+P350,P310, P322, P361, P363, P405, P501
H330 Fatal if inhaled Acute toxicity,inhalation Category 1, 2 Danger GHS hazard pictograms P260, P271, P284, P304+P340, P310,P320, P403+P233, P405, P501
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P314, P501
Precautionary statements:
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P320 Specific treatment is urgent (see … on this label).
P330 Rinse mouth.
P405 Store locked up.

Description

Bortezomib, a modified dipeptidyl boronic acid, is a therapeutic proteasome inhibitors used for the treatment of cancers. It is indicated for the treatment of relapsed multiple myeloma and mantle cell lymphoma. It is capable of inhibiting the mammalian 26S proteasome, which is important in regulating the intracellular concentration of specific proteins to maintain homeostasis within cells. The disruption of 26S proteasome function disrupts normal cellular homeostasis, leading to cytotoxic effect on various kinds of cancer cells. 

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