BV6
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- $22 - $2841
- Product name: BV6
- CAS: 1001600-56-1
- MF: C70H96N10O8
- MW: 1205.58
- EINECS:
- MDL Number:MFCD28168021
- Synonyms:4,4'-(1,6-Hexanediyl)bis[N-methyl-L-alanyl-(2S)-2-cyclohexylglycyl-L-prolyl-beta-phenyl-L-phenylalaninamide;BV6;N,N'-(hexane-1,6-diyl)bis(1-{(2S)-2-cyclohexyl-2-[(N-methyl-L-alanyl)amino]acetyl}-L-prolyl-beta-phenyl-L-phenylalaninamide):trifluoroacetic acid(1:x);CHEBI:47924;CHEBI:47924; BV-6 BV 6;CS-2877;CS-1501;BV-6;BV6
54 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- TRC
Package
- 2mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 1mg
- 5mg
- 10mM*1mLinDMSO(Solution)
- 10mg
- 25mg
- 10mM(1mLinDMSO)
- 50mg
- 100MG
- 250mg
- 10mM(in1mLDMSO)
- 1g
- 5 mg
- 10mM(in 1mL DMSO)
- Manufactureraablocks
- Product numberAA008TBZ
- Product description(2S,2'S)-N,N'-((2S,2'S)-(Hexane-1,6-Diylbis(Azanediyl))Bis(1-Oxo-3,3-Diphenylpropane-1,2-Diyl))Bis(1-((S)-2-Cyclohexyl-2-((S)-2-(Methylamino)Propanamido)Acetyl)Pyrrolidine-2-Carboxamide) 99%
- Packaging5mg
- Price$50
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TBZ
- Product description(2S,2'S)-N,N'-((2S,2'S)-(Hexane-1,6-Diylbis(Azanediyl))Bis(1-Oxo-3,3-Diphenylpropane-1,2-Diyl))Bis(1-((S)-2-Cyclohexyl-2-((S)-2-(Methylamino)Propanamido)Acetyl)Pyrrolidine-2-Carboxamide) 99%
- Packaging1mg
- Price$22
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TBZ
- Product description(2S,2'S)-N,N'-((2S,2'S)-(Hexane-1,6-Diylbis(Azanediyl))Bis(1-Oxo-3,3-Diphenylpropane-1,2-Diyl))Bis(1-((S)-2-Cyclohexyl-2-((S)-2-(Methylamino)Propanamido)Acetyl)Pyrrolidine-2-Carboxamide) 99%
- Packaging2mg
- Price$31
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TBZ
- Product description(2S,2'S)-N,N'-((2S,2'S)-(Hexane-1,6-Diylbis(Azanediyl))Bis(1-Oxo-3,3-Diphenylpropane-1,2-Diyl))Bis(1-((S)-2-Cyclohexyl-2-((S)-2-(Methylamino)Propanamido)Acetyl)Pyrrolidine-2-Carboxamide) 99%
- Packaging25mg
- Price$125
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TBZ
- Product description(2S,2'S)-N,N'-((2S,2'S)-(Hexane-1,6-Diylbis(Azanediyl))Bis(1-Oxo-3,3-Diphenylpropane-1,2-Diyl))Bis(1-((S)-2-Cyclohexyl-2-((S)-2-(Methylamino)Propanamido)Acetyl)Pyrrolidine-2-Carboxamide) 99%
- Packaging50mg
- Price$211
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberO32833
- Product descriptionBV6 98%
- Packaging25MG
- Price$380
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO32833
- Product descriptionBV6 98%
- Packaging100MG
- Price$1020
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number2291AH
- Product descriptionBV6
- Packaging10mg
- Price$455
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA357114
- Product descriptionBV-6free 98+%
- Packaging50mg
- Price$393
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA357114
- Product descriptionBV-6free 98+%
- Packaging10mg
- Price$122
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA357114
- Product descriptionBV-6free 98+%
- Packaging5mg
- Price$74
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA357114
- Product descriptionBV-6free 98+%
- Packaging2mg
- Price$52
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA357114
- Product descriptionBV-6free 98+%
- Packaging100mg
- Price$674
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA357114
- Product descriptionBV-6free 98+%
- Packaging250mg
- Price$1415
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4653
- Product descriptionBV6
- Packaging100mg
- Price$702
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB4653
- Product descriptionBV6
- Packaging5mg
- Price$112
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA008TBZ | (2S,2'S)-N,N'-((2S,2'S)-(Hexane-1,6-Diylbis(Azanediyl))Bis(1-Oxo-3,3-Diphenylpropane-1,2-Diyl))Bis(1-((S)-2-Cyclohexyl-2-((S)-2-(Methylamino)Propanamido)Acetyl)Pyrrolidine-2-Carboxamide) 99% | 5mg | $50 | 2026-05-28 | Buy |
| aablocks | AA008TBZ | (2S,2'S)-N,N'-((2S,2'S)-(Hexane-1,6-Diylbis(Azanediyl))Bis(1-Oxo-3,3-Diphenylpropane-1,2-Diyl))Bis(1-((S)-2-Cyclohexyl-2-((S)-2-(Methylamino)Propanamido)Acetyl)Pyrrolidine-2-Carboxamide) 99% | 1mg | $22 | 2026-05-28 | Buy |
| aablocks | AA008TBZ | (2S,2'S)-N,N'-((2S,2'S)-(Hexane-1,6-Diylbis(Azanediyl))Bis(1-Oxo-3,3-Diphenylpropane-1,2-Diyl))Bis(1-((S)-2-Cyclohexyl-2-((S)-2-(Methylamino)Propanamido)Acetyl)Pyrrolidine-2-Carboxamide) 99% | 2mg | $31 | 2026-05-28 | Buy |
| aablocks | AA008TBZ | (2S,2'S)-N,N'-((2S,2'S)-(Hexane-1,6-Diylbis(Azanediyl))Bis(1-Oxo-3,3-Diphenylpropane-1,2-Diyl))Bis(1-((S)-2-Cyclohexyl-2-((S)-2-(Methylamino)Propanamido)Acetyl)Pyrrolidine-2-Carboxamide) 99% | 25mg | $125 | 2026-05-28 | Buy |
| aablocks | AA008TBZ | (2S,2'S)-N,N'-((2S,2'S)-(Hexane-1,6-Diylbis(Azanediyl))Bis(1-Oxo-3,3-Diphenylpropane-1,2-Diyl))Bis(1-((S)-2-Cyclohexyl-2-((S)-2-(Methylamino)Propanamido)Acetyl)Pyrrolidine-2-Carboxamide) 99% | 50mg | $211 | 2026-05-28 | Buy |
| ACHEMBLOCK | O32833 | BV6 98% | 25MG | $380 | 2026-05-27 | Buy |
| ACHEMBLOCK | O32833 | BV6 98% | 100MG | $1020 | 2026-05-27 | Buy |
| AK Scientific | 2291AH | BV6 | 10mg | $455 | 2021-12-16 | Buy |
| Ambeed | A357114 | BV-6free 98+% | 50mg | $393 | 2021-12-16 | Buy |
| Ambeed | A357114 | BV-6free 98+% | 10mg | $122 | 2021-12-16 | Buy |
| Ambeed | A357114 | BV-6free 98+% | 5mg | $74 | 2021-12-16 | Buy |
| Ambeed | A357114 | BV-6free 98+% | 2mg | $52 | 2021-12-16 | Buy |
| Ambeed | A357114 | BV-6free 98+% | 100mg | $674 | 2021-12-16 | Buy |
| Ambeed | A357114 | BV-6free 98+% | 250mg | $1415 | 2021-12-16 | Buy |
| ApexBio Technology | B4653 | BV6 | 100mg | $702 | 2026-05-06 | Buy |
| ApexBio Technology | B4653 | BV6 | 5mg | $112 | 2026-05-06 | Buy |
Properties
Boiling point :1376.7±65.0 °C(Predicted)
Density :1.177±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :≥60.28 mg/mL in DMSO; insoluble in H2O; ≥12.6 mg/mL in EtOH with ultrasonic
form :solid
pka :12.89±0.20(Predicted)
color :White to off-white
InChIKey :DPXJXGNXKOVBJV-YLOPQIBLSA-N
Density :1.177±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :≥60.28 mg/mL in DMSO; insoluble in H2O; ≥12.6 mg/mL in EtOH with ultrasonic
form :solid
pka :12.89±0.20(Predicted)
color :White to off-white
InChIKey :DPXJXGNXKOVBJV-YLOPQIBLSA-N
Safety Information
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Description
BV6 is a bivalent Smac mimetic and an antagonist of the inhibitor of apoptosis (IAP) proteins that binds to IAP1 and XIAP (Kds = 0.46 and 1.3 nM, respectively). It induces autoubiquitination and proteasomal degradation of IAP1 and XIAP in MDA-MB-231 cells when used at a concentration of 5 μM. BV6 (4 μM) induces NF-κB activation and TNF-dependent apoptosis in A2058 and MDA-MB-231 cells. It enhances radiosensitization and increases apoptosis in HCC193 and H460 non-small cell lung cancer (NSCLC) cell lines. BV6 (1 μM) induces cell death in a panel of 40 primary, patient-derived B cell precursor acute lymphoblastic leukemia (BCP-ALL) samples in a TNF-dependent manner. In vivo, BV6 (10 mg/kg) increases survival and the time to relapse in a high-risk BCP-ALL patient-derived xenograft (PDX) mouse model.More related product prices
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Suppliers and manufacturers
Hangzhou Peptidego Biotech Co.,Ltd.
Shanghai Boyle Chemical Co., Ltd.
Dalian Meilun Biotech Co., Ltd.
Haoyuan Chemexpress Co., Ltd.
AdooQ BioScience, LLC
ShangHai Caerulum Pharma Discovery Co., Ltd.
Bide Pharmatech Ltd.
Wuxi Zhongkun Biochemical Technology Co., Ltd.
AdooQ Bioscience CHINA
Shanghai Lollane Biological Technology Co.,Ltd.